SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7MP62

- GLMS_VIBVY

UniProt

Q7MP62 - GLMS_VIBVY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, VV0502
Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei605 – 6051For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciVVUL196600:GJ9W-520-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:VV0502
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002675: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 610609Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135412Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi196600.VV0502.

Structurei

3D structure databases

ProteinModelPortaliQ7MP62.
SMRiQ7MP62. Positions 2-610.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 218217Glutamine amidotransferase type-2
Add
BLAST
Domaini286 – 426141SIS 1
Add
BLAST
Domaini459 – 600142SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiPVTRRFM.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7MP62-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIVGAVAQ RDVAEILVEG LRRLEYRGYD SAGVAVVDSQ SNLTRIRRLG    50
KVQELADAVD QAEVVGGTGI AHTRWATHGE PSEINAHPHQ SGDISVVHNG 100
IIENHETLRE LLQSRGYVFE SQTDTEVIAH LVEWELRTAA SLLEAVQKTV 150
KQLEGAYGTV VLDRNDPSRI VVARSGSPIV IGFGVGENFL ASDQLALLNV 200
TRRFMYLEEG DVAEITRREV AVYDALGERV EREIAESNAE HDAGDKGQYR 250
HFMQKEIYEQ PTALINTMEG RITADSVVTE AIGVNAAEIL SKVEHVQIVA 300
CGTSYNAGMT ARYWFEDIAG VSCDVEIASE FRYRKFVTRP NSLLITLSQS 350
GETADTLAAL RLAKEKGYMA AMTICNVAGS SLVRESDFAF MTRAGVEIGV 400
ASTKAFTTQL AALLMLVTAL GKQQGRISKE KEKEIVEALH ALPKQINAAL 450
SFEKDIEALA TDFADKHHTL FLGRGEFYPI AMEASLKLKE ISYIHAEAYA 500
AGELKHGPLA LIDADMPVVV VAPSNDLLEK LKSNVEEVRA RGGLLYVFAD 550
ADAGFEGDET MKIITMPHVS EITAAIYYTI PMQLLSYYVA LIKGTDVDQP 600
RNLAKAVTVE 610
Length:610
Mass (Da):66,662
Last modified:January 23, 2007 - v3
Checksum:i485FBAC6A1CF1F24
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC93266.1.
RefSeqiNP_933295.1. NC_005139.1.
WP_011149416.1. NC_005139.1.

Genome annotation databases

EnsemblBacteriaiBAC93266; BAC93266; BAC93266.
GeneIDi2623269.
KEGGivvy:VV0502.
PATRICi20167810. VBIVibVul40472_0526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC93266.1 .
RefSeqi NP_933295.1. NC_005139.1.
WP_011149416.1. NC_005139.1.

3D structure databases

ProteinModelPortali Q7MP62.
SMRi Q7MP62. Positions 2-610.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196600.VV0502.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC93266 ; BAC93266 ; BAC93266 .
GeneIDi 2623269.
KEGGi vvy:VV0502.
PATRICi 20167810. VBIVibVul40472_0526.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi PVTRRFM.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci VVUL196600:GJ9W-520-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJ016.

Entry informationi

Entry nameiGLMS_VIBVY
AccessioniPrimary (citable) accession number: Q7MP62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 76 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi