Q7MP37 (DEOC1_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase 1
Short name=DERA 1
EC=4.1.2.4

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 1
Phosphodeoxyriboaldolase 1
Short name=Deoxyriboaldolase 1

Gene names

Name:	deoC1
Ordered Locus Names:	VV0527

Organism

Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]

Taxonomic identifier

196600 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity HAMAP MF_00114.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	Deoxyribose-phosphate aldolase 1 HAMAP MF_00114		PRO_0000057284
Sites
	Active site	149	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	178	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7MP37 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 48EB05859F5ECF3A	FASTA	219	23,433
	10 20 30 40 50 60 MNHYIDHTLL LANATTKQIN TLCDEAHEHQ FFSVCINPDF VEHCAERLNT SNVKICTVIG 70 80 90 100 110 120 FPLGANTTAV KVFETQNAIS LGADEIDMVV NISDVLDGKW DVIEKEIVAI KEACGPKLLK 130 140 150 160 170 180 VIFETCLLTN EQIVKLCNIS KRAGADFVKT STGFSTGGAT VEHIKLMRDT VGKQMGVKAS 190 200 210 GGVRTKETAQ AMIDAGASRV GASASVSIVT GEAPTTNGY

References

[1]

"Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YJ016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000037 Genomic DNA. Translation: BAC93291.1.
RefSeq	NP_933320.1. NC_005139.1.
3D structure databases
ProteinModelPortal	Q7MP37.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7MP37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2623294.
GenomeReviews	Gene locus VV0527 in contig BA000037_GR.
KEGG	vvy:VV0527.
NMPDR	fig|196600.1.peg.595.
PATRIC	20167856. VBIVibVul40472_0549.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	CLEAREN.
PhylomeDB	Q7MP37.
Enzyme and pathway databases
BioCyc	VVUL196600:VV0527-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC1_VIBVY

Accession

Primary (citable) accession number: Q7MP37

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	December 15, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program