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Protein

tRNA1(Val) (adenine(37)-N6)-methyltransferase

Gene

VV0662

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 37 of tRNA1(Val) (anticodon cmo5UAC).UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(37) in tRNA1(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine(37) in tRNA1(Val).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processtRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA1(Val) (adenine(37)-N6)-methyltransferaseUniRule annotation (EC:2.1.1.223UniRule annotation)
Alternative name(s):
tRNA m6A37 methyltransferaseUniRule annotation
Gene namesi
Ordered Locus Names:VV0662
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000002675 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003874491 – 239tRNA1(Val) (adenine(37)-N6)-methyltransferaseAdd BLAST239

Structurei

3D structure databases

ProteinModelPortaliQ7MNQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000283147.
KOiK15460.
OrthoDBiPOG092V0302.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01872. tRNA_methyltr_YfiC. 1 hit.
InterProiView protein in InterPro
IPR002052. DNA_methylase_N6_adenine_CS.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
IPR022882. tRNA_adenine-N6_MeTrfase.
PfamiView protein in Pfam
PF05175. MTS. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiView protein in PROSITE
PS00092. N6_MTASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7MNQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSGTLKTKG FKFKQFSIAS SNSGMPVSTD GVLLGAWADF HHSQNLLDIG
60 70 80 90 100
TGTGLLSLMC AQRYAHLSIT AVDIDAHAME AAQENFSHSP WHSRLHLQHG
110 120 130 140 150
DVLKLNFTHR FDGIICNPPY FNSGEQAQAT QRATARHTDT LAHDALLLRC
160 170 180 190 200
RELLTPNGKA NFVLPLTEGE QFLQLAQQQG WHLHRLCRVK PSPNKPVHRL
210 220 230
LFELGLSTAT TSEEHLTIND GSTYSAAFVK LCQDFYLKM
Length:239
Mass (Da):26,579
Last modified:November 3, 2009 - v2
Checksum:i4E3A06744E72DD9B
GO

Sequence cautioni

The sequence BAC93425 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000037 Genomic DNA. Translation: BAC93425.1. Different initiation.
RefSeqiWP_043877070.1. NC_005139.1.

Genome annotation databases

EnsemblBacteriaiBAC93425; BAC93425; BAC93425.
GeneIDi2623430.
KEGGivvy:VV0662.
PATRICi20168120. VBIVibVul40472_0680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000037 Genomic DNA. Translation: BAC93425.1. Different initiation.
RefSeqiWP_043877070.1. NC_005139.1.

3D structure databases

ProteinModelPortaliQ7MNQ4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC93425; BAC93425; BAC93425.
GeneIDi2623430.
KEGGivvy:VV0662.
PATRICi20168120. VBIVibVul40472_0680.

Phylogenomic databases

HOGENOMiHOG000283147.
KOiK15460.
OrthoDBiPOG092V0302.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01872. tRNA_methyltr_YfiC. 1 hit.
InterProiView protein in InterPro
IPR002052. DNA_methylase_N6_adenine_CS.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
IPR022882. tRNA_adenine-N6_MeTrfase.
PfamiView protein in Pfam
PF05175. MTS. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiView protein in PROSITE
PS00092. N6_MTASE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRMN6_VIBVY
AccessioniPrimary (citable) accession number: Q7MNQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: November 3, 2009
Last modified: February 15, 2017
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.