Reviewed,
UniProtKB/Swiss-Prot Q7MLY4 (DNAE2_VIBVY)
Last modified
November 25, 2008.
Version 39.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Error-prone DNA polymerase EC=2.7.7.7 | ||||
| Gene names |
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| Organism | Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 196600 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio |
Protein attributes
| Sequence length | 1024 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
| Subcellular location | CytoplasmProbable. |
| Sequence similarities | Belongs to the DNA polymerase type-C family. DnaE2 subfamily. |
Ontologies
Keywords | |
|---|---|
| Biological process | DNA damage DNA repair DNA replication |
| Cellular component | Cytoplasm |
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | DNA replication Inferred from electronic annotation. Source: InterPro error-prone DNA repairInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: HAMAP |
| Molecular function | 3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA bindingInferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 1024 | 1024 | Error-prone DNA polymerase | PRO_0000103403 | |||
Sequences
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References
| [1] | "Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| BA000037 Genomic DNA. Translation: BAC94056.1. | |
| RefSeq | NP_934085.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2624096. |
| GenomeReviews | Gene locus VV1294 in contig BA000037_GR. |
| KEGG | vvy:VV1294. |
| NMPDR | fig|196600.1.peg.1360. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q7MLY4. |
Enzyme and pathway databases | |
| BioCyc | VVUL196600:VV1294-MON. |
Family and domain databases | |
| HAMAP | MF_01902. [Tree] |
| InterPro | IPR011708. DNA_pol3_alpha. IPR004365. NA_bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. PHP_N. IPR004805. PolC_alpha. [Graphical view] |
| Pfam | PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view] |
| SMART | SM00481. POLIIIAc. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00594. polc. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | DNAE2_VIBVY | ||||||||
| Accession | Primary (citable) accession number: Q7MLY4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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