Reviewed, UniProtKB/Swiss-Prot Q7MJM8 (ACKA1_VIBVY)

Names and origin

Protein names

Recommended name:
    Acetate kinase 1
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 1

Gene names

Name:	ackA1
Ordered Locus Names:	VV2133

Organism

Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]

Taxonomic identifier

196600 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Acetate kinase 1 HAMAP MF_00020		PRO_0000107643

Sequences

	Sequence		Length	Mass (Da)
	Q7MJM8-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 5295DC83097BBF86	FASTA	398	42,881
	10 20 30 40 50 60 MSKLVLVLNC GSSSLKFAVV DAENGAEHLS GLAECLHLPE ARIKWKLDGK HEAQLGNGAA 70 80 90 100 110 120 HEEALAFMVE TILASKPELS ENLAAIGHRV VHGGEQFTQS ALITDEVLKG IEDCATLAPL 130 140 150 160 170 180 HNPAHIIGIK AAQKSFPALK NVAVFDTAFH QTMPEEAYLY ALPYNLYKEH GIRRYGMHGT 190 200 210 220 230 240 SHLFITREVA SLLNKPVEEV NIINCHLGNG ASVCAVKNGQ SVDTSMGLTP LEGLVMGTRC 250 260 270 280 290 300 GDIDPAIIFH LHDTLGYSVE KINTMLTKES GLAGLTEVTS DCRFVEDNYG QKEEATRAMD 310 320 330 340 350 360 VFCHRLAKYV AGYTATLEGR LDAITFTGGI GENSAPIREM VLNRLGIFGI EVDSEANLKA 370 380 390 RFGGEGVITT ANSRIPAMVI STNEELVIAE DTARLAGL

References

[1]

"Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000037 Genomic DNA. Translation: BAC94897.1.
RefSeq	NP_934926.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7MJM8.
Genome annotation databases
GeneID	2624939.
GenomeReviews	Gene locus VV2133 in contig BA000037_GR.
KEGG	vvy:VV2133.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7MJM8.
OMA	PHLKDKN.
Enzyme and pathway databases
BioCyc	VVUL196600:VV2133-MON.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA1_VIBVY

Accession

Primary (citable) accession number: Q7MJM8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 21, 2004
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)