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Q7MJI2

- FUCI_VIBVY

UniProt

Q7MJI2 - FUCI_VIBVY

Protein

L-fucose isomerase

Gene

fucI

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Converts the aldose L-fucose into the corresponding ketose L-fuculose.UniRule annotation

    Catalytic activityi

    L-fucopyranose = L-fuculose.UniRule annotation

    Cofactori

    Manganese.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei333 – 3331Proton acceptorUniRule annotation
    Metal bindingi333 – 3331ManganeseUniRule annotation
    Active sitei357 – 3571Proton acceptorUniRule annotation
    Metal bindingi357 – 3571ManganeseUniRule annotation
    Metal bindingi520 – 5201ManganeseUniRule annotation

    GO - Molecular functioni

    1. L-fucose isomerase activity Source: UniProtKB-HAMAP
    2. manganese ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. L-fucose catabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Carbohydrate metabolism, Fucose metabolism

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciVVUL196600:GJ9W-2236-MONOMER.
    UniPathwayiUPA00563; UER00624.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L-fucose isomeraseUniRule annotation (EC:5.3.1.25UniRule annotation)
    Alternative name(s):
    6-deoxy-L-galactose isomeraseUniRule annotation
    FucIase
    Gene namesi
    Name:fucIUniRule annotation
    Ordered Locus Names:VV2179
    OrganismiVibrio vulnificus (strain YJ016)
    Taxonomic identifieri196600 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000002675: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 582582L-fucose isomerasePRO_0000204154Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi196600.VV2179.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7MJI2.
    SMRiQ7MJI2. Positions 3-582.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the L-fucose isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2407.
    HOGENOMiHOG000249674.
    KOiK01818.
    OMAiKEGQDYR.
    OrthoDBiEOG6FJNCF.

    Family and domain databases

    Gene3Di3.20.14.10. 1 hit.
    3.40.275.10. 1 hit.
    3.40.50.1070. 1 hit.
    HAMAPiMF_01254. Fucose_iso.
    InterProiIPR004216. Fuc/Ara_isomerase_C.
    IPR015888. Fuc_isomerase_C.
    IPR012888. Fucose_iso_N1.
    IPR005763. Fucose_isomerase.
    IPR009015. Fucose_isomerase_N/cen.
    IPR012889. Fucose_isomerase_N2.
    [Graphical view]
    PfamiPF02952. Fucose_iso_C. 1 hit.
    PF07881. Fucose_iso_N1. 1 hit.
    PF07882. Fucose_iso_N2. 1 hit.
    [Graphical view]
    SUPFAMiSSF50443. SSF50443. 1 hit.
    SSF53743. SSF53743. 1 hit.
    TIGRFAMsiTIGR01089. fucI. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7MJI2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNLVKIGIR PTIDGRRLGV RESLEEQTMN MAKNLANFIA ENVRHVSGDA    50
    VECVIADSTI GGVAEAAACA DKFKRENVGL SITVTPCWCY GTETIDMDPH 100
    MPKAIWGFNG TERPGAVYLA AAMAGHSQVG LPAFSIYGEE VQDKDDTSIP 150
    SDVQEKILRF CRAGLTVATI RGKSYLSMGS VSMGIAGSIV DQPFFQHYLG 200
    MRNEYVDMTE IKRRLDREIF DKEEFELAMA WTKEHCHEGK DYNREPMSEA 250
    RKQEDWQTVV KMTMIMRDLM EGNPKLAEMG FGEEALGHNA VVGGFQGQRH 300
    WTDHLPNGDF SEAILNSSFD WNGIREPFVI ATENDSLNGV NMLFGKMLTG 350
    QAQVFCDVRT YWSADSVERV SGYRPESGFI HLVNSGSAAL DGCGEAKLTS 400
    GESAIKPHWQ MSAQDAEACL SATKWPPADV EYFRGGGFSS NFLTHGGMPF 450
    TMHRINIIKG IGPVLQIAEG HSITLPQEVH ETLNERTNPT WPTTWFVPRL 500
    NDEGAFKDVY SVMANWGANH CVITYGHVGA DLITLASMLR IPVAMHNVEE 550
    SDVFRPHTWS AFGQDKEGQD YRACATFGPL YK 582
    Length:582
    Mass (Da):64,482
    Last modified:December 15, 2003 - v1
    Checksum:i96F9E99608057E52
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000037 Genomic DNA. Translation: BAC94943.1.
    RefSeqiNP_934972.1. NC_005139.1.

    Genome annotation databases

    EnsemblBacteriaiBAC94943; BAC94943; BAC94943.
    GeneIDi2624985.
    KEGGivvy:VV2179.
    PATRICi20171222. VBIVibVul40472_2196.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000037 Genomic DNA. Translation: BAC94943.1 .
    RefSeqi NP_934972.1. NC_005139.1.

    3D structure databases

    ProteinModelPortali Q7MJI2.
    SMRi Q7MJI2. Positions 3-582.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 196600.VV2179.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC94943 ; BAC94943 ; BAC94943 .
    GeneIDi 2624985.
    KEGGi vvy:VV2179.
    PATRICi 20171222. VBIVibVul40472_2196.

    Phylogenomic databases

    eggNOGi COG2407.
    HOGENOMi HOG000249674.
    KOi K01818.
    OMAi KEGQDYR.
    OrthoDBi EOG6FJNCF.

    Enzyme and pathway databases

    UniPathwayi UPA00563 ; UER00624 .
    BioCyci VVUL196600:GJ9W-2236-MONOMER.

    Family and domain databases

    Gene3Di 3.20.14.10. 1 hit.
    3.40.275.10. 1 hit.
    3.40.50.1070. 1 hit.
    HAMAPi MF_01254. Fucose_iso.
    InterProi IPR004216. Fuc/Ara_isomerase_C.
    IPR015888. Fuc_isomerase_C.
    IPR012888. Fucose_iso_N1.
    IPR005763. Fucose_isomerase.
    IPR009015. Fucose_isomerase_N/cen.
    IPR012889. Fucose_isomerase_N2.
    [Graphical view ]
    Pfami PF02952. Fucose_iso_C. 1 hit.
    PF07881. Fucose_iso_N1. 1 hit.
    PF07882. Fucose_iso_N2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50443. SSF50443. 1 hit.
    SSF53743. SSF53743. 1 hit.
    TIGRFAMsi TIGR01089. fucI. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: YJ016.

    Entry informationi

    Entry nameiFUCI_VIBVY
    AccessioniPrimary (citable) accession number: Q7MJI2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 4, 2005
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3