Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7MIH2

- LPXB_VIBVY

UniProt

Q7MIH2 - LPXB_VIBVY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciVVUL196600:GJ9W-2603-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:VV2544
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002675: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Lipid-A-disaccharide synthasePRO_0000190191Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196600.VV2544.

Structurei

3D structure databases

ProteinModelPortaliQ7MIH2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018003.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7MIH2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNKPLRIGI VAGELSGDTL GEGFIKAIKA VHPDAEFVGI GGPKMIALGC
60 70 80 90 100
QSLFDMEELA VMGLVEVLGR LPRLLKVKAE LVRYFTENPP DVFVGIDAPD
110 120 130 140 150
FNLRLELDLK NAGIKTVHYV SPSVWAWRQK RIFKIAKATH LVLAFLPFEK
160 170 180 190 200
AFYDKFNVPC EFIGHTLADA IPLESDKAPA RELLGLEQDK QWLAVLPGSR
210 220 230 240 250
GSELKMLSQP FIETCKKLQQ AFPELGFVVA LVNQKRREQF EQAWKEYAPE
260 270 280 290 300
LDFKLVDDTA RNVITASDAV MLASGTVALE CMLLKRPMVV GYRVNAVTAF
310 320 330 340 350
LAKRLLKTQY VSLPNILADT ELVKEYLQDD CTPDNLFGEV SRLLEGDNHQ
360 370 380
MLDKFTEMHH WIRKDADQQA ANAVLKLIEK
Length:380
Mass (Da):42,610
Last modified:December 15, 2003 - v1
Checksum:iFCF052209B276171
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC95308.1.
RefSeqiNP_935337.1. NC_005139.1.

Genome annotation databases

EnsemblBacteriaiBAC95308; BAC95308; BAC95308.
GeneIDi2625352.
KEGGivvy:VV2544.
PATRICi20171930. VBIVibVul40472_2548.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC95308.1 .
RefSeqi NP_935337.1. NC_005139.1.

3D structure databases

ProteinModelPortali Q7MIH2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196600.VV2544.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC95308 ; BAC95308 ; BAC95308 .
GeneIDi 2625352.
KEGGi vvy:VV2544.
PATRICi 20171930. VBIVibVul40472_2548.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018003.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci VVUL196600:GJ9W-2603-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJ016.

Entry informationi

Entry nameiLPXB_VIBVY
AccessioniPrimary (citable) accession number: Q7MIH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: December 15, 2003
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3