Q7MIF8 (GLND_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	VV2559

Organism

Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]

Taxonomic identifier

196600 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio vulnificus

Protein attributes

Sequence length	873 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 873	873	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192775

Sequences

	Sequence		Length	Mass (Da)
	Q7MIF8 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: EF8625319678607A	FASTA	873	101,060
	10 20 30 40 50 60 MAFQSPLTFN DEQLTVAQLK SQLDLFANAQ KQAFLNHHPV TDLVLSRAEY MDLLLTRLWR 70 80 90 100 110 120 YYGFSEIHNI SLVAVGGYGR GELHPLSDID ILVLSKHKLP GELETKLSEF ITLLWDLRLE 130 140 150 160 170 180 VGHAVRTVEE CAAIGREDLT VATNLQEARL LCGSENTFQD LKKVVLSDSF WPSETFYRAK 190 200 210 220 230 240 IQEQRERHAR YHDTTYNLEP DIKSTPGGLR DIHTLSWVAR RHFGATSLLE MSRYGFLTDA 250 260 270 280 290 300 EYRELVECQD FLWRVRFALH IELKRYDNRL TFAHQIQVAE HLGFKGEGNR GIEMMMKEFY 310 320 330 340 350 360 RTLRRVAELN KMLLKLFDQA IINGGETEPA VIINEDFQRR GRLIEARKPA LFQARPETIL 370 380 390 400 410 420 DMFLHIANDS TIDSVSPPTL RQLRTARRRL NKFLHTIPEA REKFMELVRH PNALHRAFSL 430 440 450 460 470 480 MHKLGVLAAY LPQWSQIVGQ MQFDLFHVYT VDEHSVRLLN HINTFSYAKN HDKHPICCEV 490 500 510 520 530 540 YPRLQKKELL LLAAIFHDIG KGRGGDHSEI GEKEAYDFCI EHGLSKPEAK LVSWLVRHHL 550 560 570 580 590 600 LMSVTAQRRD IYDPEVITEF AKQVRDEERL EYLVCLTVAD ICATNPELWN SWKRTLLAEL 610 620 630 640 650 660 FYSTQRALRR GLENPVDVRE RIRHNQQLAS ALLRKEGFTA REIEVLWQRF KADYFLRHTH 670 680 690 700 710 720 KQIAWHCEHI LRMDNPEQPL VLMSKKATRG GTEVFVYTKD QHALFATVVA ELDRRNFNVH 730 740 750 760 770 780 DAQIMSSKDG YVLDTFMVLD QHGQAIDVDN HKAVIKHLMH VLTDGRPTKV KTRRTPYKLQ 790 800 810 820 830 840 HFKVKTKVDF LPTKSKKRTL MELVALDTPG LLAITGATFA DMGFNLHGAK ITTIGERAED 850 860 870 LFILTSENGG RLSEEQELQL REKLIHNIAE LAP

References

[1]

"Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YJ016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000037 Genomic DNA. Translation: BAC95323.1.
RefSeq	NP_935352.1. NC_005139.1.
3D structure databases
ProteinModelPortal	Q7MIF8.
ModBase	Search...
Protein-protein interaction databases
STRING	196600.VV2559.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC95323; BAC95323; BAC95323.
GeneID	2625367.
KEGG	vvy:VV2559.
PATRIC	20171960. VBIVibVul40472_2563.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05007.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_VIBVY

Accession

Primary (citable) accession number: Q7MIF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 5, 2004
Last sequence update:	December 15, 2003
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program