Reviewed, UniProtKB/Swiss-Prot Q7MI38 (DEOC2_VIBVY)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase 2
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase 2
      Short name=Deoxyriboaldolase 2
      Short name=DERA 2

Gene names

Name:	deoC2
Ordered Locus Names:	VV2679

Organism

Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]

Taxonomic identifier

196600 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00592
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00592
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	Deoxyribose-phosphate aldolase 2 HAMAP MF_00592		PRO_0000057308
Sites
	Active site	165	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	199	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7MI38-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: C68A150EAA617724	FASTA	258	27,756
	10 20 30 40 50 60 MSDLKAAALR ALKLMDLTTL NDDDTDAKVI ALCHDAKTPV GNTAAICIYP RFIPIAKKTL 70 80 90 100 110 120 REQGTPEVRI ATVTNFPHGN DDIEIAVAET KAAVAYGADE VDVVFPYRAL MAGDEKVGFE 130 140 150 160 170 180 LVKQCKEACG DILLKVIIET GELKEEALIK KASQICIEAG ADFIKTSTGK VPVNATPEYA 190 200 210 220 230 240 RMMLEVIRDM GVAEKVGFKP AGGVRTAEDA AAYLAMADDI LGSEWADNMH YRFGASSLLT 250 NLLNTLEVTD QVADPAAY

References

[1]

"Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000037 Genomic DNA. Translation: BAC95443.1.
RefSeq	NP_935472.1.
3D structure databases
SMR	Q7MI38. Positions 1-234.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7MI38.
Genome annotation databases
GeneID	2625487.
GenomeReviews	Gene locus VV2679 in contig BA000037_GR.
KEGG	vvy:VV2679.
NMPDR	fig|196600.1.peg.2747.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7MI38.
OMA	CKEACGD.
Enzyme and pathway databases
BioCyc	VVUL196600:VV2679-MON.
Family and domain databases
HAMAP	MF_00592. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC2_VIBVY

Accession

Primary (citable) accession number: Q7MI38

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)