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Q7MHI7

- GLSA_VIBVY

UniProt

Q7MHI7 - GLSA_VIBVY

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Protein

Glutaminase

Gene
glsA, VV2882
Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciVVUL196600:GJ9W-2951-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:VV2882
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002675: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotationPRO_0000110632Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi196600.VV2882.

Structurei

3D structure databases

ProteinModelPortaliQ7MHI7.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7MHI7-1 [UniParc]FASTAAdd to Basket

« Hide

MKPTKELLNE ILHEVRPLIG RGKVANYIPA LARVPAHKLA IAVYTNQGEV    50
IKAGDADEAF SIQSISKALS LTLAMGLYQP DEIWRRVGKE PSGQAFNSLI 100
QLEMEQGIPR NPFINAGAIV VADLLASRLS APRQRLLEFV RQLSGETHIC 150
YDKVVAASEM MHSDRNAAIA YLMRSFGNFE NEVIPVLNNY FHACALKMSC 200
VDLAKTFSYL ANKGVSVHTD QRVISPVQTK QLNALLATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TKALELLSER 300
IGRSIF 306
Length:306
Mass (Da):33,169
Last modified:May 24, 2004 - v2
Checksum:i30D8C878AF0B5A4A
GO

Sequence cautioni

The sequence BAC95646.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC95646.1. Different initiation.
RefSeqiNP_935675.1. NC_005139.1.

Genome annotation databases

EnsemblBacteriaiBAC95646; BAC95646; BAC95646.
GeneIDi2625700.
KEGGivvy:VV2882.
PATRICi20172590. VBIVibVul40472_2868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000037 Genomic DNA. Translation: BAC95646.1 . Different initiation.
RefSeqi NP_935675.1. NC_005139.1.

3D structure databases

ProteinModelPortali Q7MHI7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196600.VV2882.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC95646 ; BAC95646 ; BAC95646 .
GeneIDi 2625700.
KEGGi vvy:VV2882.
PATRICi 20172590. VBIVibVul40472_2868.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci VVUL196600:GJ9W-2951-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJ016.

Entry informationi

Entry nameiGLSA_VIBVY
AccessioniPrimary (citable) accession number: Q7MHI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: May 14, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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