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Q7MHI7 (GLSA_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:VV2882
OrganismVibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]
Taxonomic identifier196600 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Sequence caution

The sequence BAC95646.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Glutaminase HAMAP-Rule MF_00313
PRO_0000110632

Sites

Binding site641Substrate By similarity
Binding site1151Substrate By similarity
Binding site1591Substrate By similarity
Binding site1661Substrate By similarity
Binding site1901Substrate By similarity
Binding site2421Substrate By similarity
Binding site2601Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MHI7 [UniParc].

Last modified May 24, 2004. Version 2.
Checksum: 30D8C878AF0B5A4A

FASTA30633,169
        10         20         30         40         50         60 
MKPTKELLNE ILHEVRPLIG RGKVANYIPA LARVPAHKLA IAVYTNQGEV IKAGDADEAF 

        70         80         90        100        110        120 
SIQSISKALS LTLAMGLYQP DEIWRRVGKE PSGQAFNSLI QLEMEQGIPR NPFINAGAIV 

       130        140        150        160        170        180 
VADLLASRLS APRQRLLEFV RQLSGETHIC YDKVVAASEM MHSDRNAAIA YLMRSFGNFE 

       190        200        210        220        230        240 
NEVIPVLNNY FHACALKMSC VDLAKTFSYL ANKGVSVHTD QRVISPVQTK QLNALLATCG 

       250        260        270        280        290        300 
LYDGAGEFAY RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TKALELLSER 


IGRSIF 

« Hide

References

[1]"Comparative genome analysis of Vibrio vulnificus, a marine pathogen."
Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F.
Genome Res. 13:2577-2587(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YJ016.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000037 Genomic DNA. Translation: BAC95646.1. Different initiation.
RefSeqNP_935675.1. NC_005139.1.

3D structure databases

ProteinModelPortalQ7MHI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196600.VV2882.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC95646; BAC95646; BAC95646.
GeneID2625700.
KEGGvvy:VV2882.
PATRIC20172590. VBIVibVul40472_2868.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAMSIAVWS.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycVVUL196600:GJ9W-2951-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_VIBVY
AccessionPrimary (citable) accession number: Q7MHI7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: May 14, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families