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Q7MH97 (G6PI_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:VV2975
OrganismVibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]
Taxonomic identifier196600 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180766

Sites

Active site3561Proton donor By similarity
Active site3871 By similarity
Active site5151 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MH97 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 1099BC46F5450EC3

FASTA55060,744
        10         20         30         40         50         60 
MLKTINPTQT QAWNALTAHF ESAQDMDLKD LFAQDAARFD KFSARFGSDI LVDYSKNLIN 

        70         80         90        100        110        120 
EETLKHLFAL AKETELSAAI KAMFSGEAIN QTEGRAVLHT ALRNRSNQPV LVDGEDVMPA 

       130        140        150        160        170        180 
VNAVLEKMKS FTDRVIGGEW KGYTGKAITD IVNIGIGGSD LGPYMVTEAL APYKNHLNLH 

       190        200        210        220        230        240 
FVSNVDGTHI VETLKKVDPE TTLFLIASKT FTTQETMTNA HTARDWFLAT AGDQAHVAKH 

       250        260        270        280        290        300 
FAALSTNAPA VSEFGIDTDN MFEFWDWVGG RYSLWSAIGL SIALAVGYDN FVELLEGAHE 

       310        320        330        340        350        360 
MDNHFVSTEL ESNIPVILAL IGIWYNNFHG AESEAILPYD QYMHRFAAYF QQGNMESNGK 

       370        380        390        400        410        420 
YVDRNGNPVT YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI PCDFIAPAVS HNPAGDHHQK 

       430        440        450        460        470        480 
LMSNFFAQTE ALAFGKNEAT VKAELVKAGK NAEEVAAIAP FKVFEGNRPT NSILVKQITP 

       490        500        510        520        530        540 
RTLGNLIAMY EHKIFVQGVI WNIFSFDQWG VELGKQLANQ ILPELADDSE ISSHDSSTNG 

       550 
LINAFKAFKA 

« Hide

References

[1]"Comparative genome analysis of Vibrio vulnificus, a marine pathogen."
Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F.
Genome Res. 13:2577-2587(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YJ016.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000037 Genomic DNA. Translation: BAC95739.1.
RefSeqNP_935768.1. NC_005139.1.

3D structure databases

ProteinModelPortalQ7MH97.
SMRQ7MH97. Positions 21-546.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196600.VV2975.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC95739; BAC95739; BAC95739.
GeneID2625824.
KEGGvvy:VV2975.
PATRIC20172820. VBIVibVul40472_2953.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycVVUL196600:GJ9W-3073-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_VIBVY
AccessionPrimary (citable) accession number: Q7MH97
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways