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Q7MH68 (CAPP_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:VV3004
OrganismVibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]
Taxonomic identifier196600 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length877 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Sequence caution

The sequence BAC95768.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 877877Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166650

Sites

Active site1381 By similarity
Active site5441 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7MH68 [UniParc].

Last modified May 24, 2004. Version 2.
Checksum: 6B9038A4BFD62002

FASTA87798,927
        10         20         30         40         50         60 
MNEKYAALKS NVSMLGHLLG NTIQEAHGDE ILEKVETIRK LSKSARAGNQ ADRNNLIEEI 

        70         80         90        100        110        120 
KSLPDEQLTP VARAFNQFLN LTNIAEQYHT ISRHCDAHVC EPDAINTLFA KLGQNGINKL 

       130        140        150        160        170        180 
DTAQAIRELN IELVLTAHPT EITRRTMINK LVKINECLSK LELSDLSYKE RHKTEKRLEQ 

       190        200        210        220        230        240 
LIAQSWHSDV IRKQRPTPLD EAKWGFAVVE NSLWEAVPDF LRELDEKLKD YLDQGLPIDA 

       250        260        270        280        290        300 
RPVHFSSWMG GDRDGNPFVT HTVTREVLLL SRWKAADLYL KDINELISEL SMTKCNDTVR 

       310        320        330        340        350        360 
QLAGEDEHEP YRAILKQLRT LLSDTKEILD AKINGQKLAV KAPLQSVEQL WDPLFACYQS 

       370        380        390        400        410        420 
LRECGMSMIA EGSLLDTLRR VKAFGVHLVR LDIRQESTRH ADVLSELTRY LGIGDYNHWS 

       430        440        450        460        470        480 
EQDKIAFLTN ELASKRPLLP RDWQPSEPVK EVLDTCKIIA AQSREAFGAY VISMAKTASD 

       490        500        510        520        530        540 
VLAVHLLLQE SGCPYRMDVC PLFETLDDLN NAEAVIKQLM SIDLYRGFIQ NHQMVMIGYS 

       550        560        570        580        590        600 
DSAKDAGVMA AGWAQYHAME ALVNVAEQEG IELTLFHGRG GTIGRGGAPA HAALLSQPPK 

       610        620        630        640        650        660 
SLKGGLRVTE QGEMIRFKLG LPDVAVNSFN MYASAILEAN LLPPPEPKQE WRDLMEVLSQ 

       670        680        690        700        710        720 
VSCEAYRSVV RGEPDFVPYF RQATPELELG KLPLGSRPAK RNPNGGVESL RAIPWIFSWS 

       730        740        750        760        770        780 
QNRLLLPAWL GAGEAIQYSI DKGHQALLEE MCREWPFFST RLGMLEMVYL KCNSEISRYY 

       790        800        810        820        830        840 
DERLADKSLL PLGDRLRDQL QSDIKAVLNV ENNENLMQSD PWGQESIRLR NIYIEPLNML 

       850        860        870 
QAELLYRTRQ AGVVSEELEE ALMVTIAGIA AGMRNTG 

« Hide

References

[1]"Comparative genome analysis of Vibrio vulnificus, a marine pathogen."
Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F.
Genome Res. 13:2577-2587(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YJ016.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000037 Genomic DNA. Translation: BAC95768.1. Different initiation.
RefSeqNP_935797.2. NC_005139.1.

3D structure databases

ProteinModelPortalQ7MH68.
SMRQ7MH68. Positions 4-877.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING196600.VV3004.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC95768; BAC95768; BAC95768.
GeneID2625853.
KEGGvvy:VV3004.
PATRIC20172876. VBIVibVul40472_2981.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycVVUL196600:GJ9W-3102-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_VIBVY
AccessionPrimary (citable) accession number: Q7MH68
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: February 19, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families