Reviewed,
UniProtKB/Swiss-Prot Q7MGL2 (PUR6_VIBVY)
Last modified
February 9, 2010.
Version 39.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Phosphoribosylaminoimidazole carboxylase catalytic subunit EC=4.1.1.21 Alternative name(s): AIR carboxylase Short name=AIRC | ||||
| Gene names |
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| Organism | Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 196600 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio |
Protein attributes
| Sequence length | 161 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition By similarity. |
| Catalytic activity | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2. |
| Pathway | |
| Subunit structure | Homooctamer By similarity. |
| Sequence similarities | Belongs to the AIR carboxylase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Purine biosynthesis |
| Molecular function | Decarboxylase Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | 'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000037 Genomic DNA. Translation: BAC95982.1. |
| RefSeq | NP_936011.1. |
3D structure databases | |
| SMR | Q7MGL2. Positions 3-145. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q7MGL2. |
Genome annotation databases | |
| GeneID | 2626094. |
| GenomeReviews | Gene locus VV3218 in contig BA000037_GR. |
| KEGG | vvy:VV3218. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0041. |
| HOGENOM | HBG301965. |
| OMA | QSDWATM. |
Enzyme and pathway databases | |
| BioCyc | VVUL196600:VV3218-MONOMER. |
Family and domain databases | |
| InterPro | IPR000031. AIR_COase_core. [Graphical view] |
| Gene3D | G3DSA:3.40.50.7700. AIR_carboxyl. 1 hit. |
| PANTHER | PTHR23046. AIR_carboxyl. 1 hit. |
| Pfam | PF00731. AIRC. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01162. purE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PUR6_VIBVY | ||||||||
| Accession | Primary (citable) accession number: Q7MGL2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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