Q7MEV1 (RBSA_VIBVY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose import ATP-binding protein RbsA
EC=3.6.3.17

Gene names

Name:	rbsA
Ordered Locus Names:	VVA0569

Organism

Vibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]

Taxonomic identifier

196600 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio vulnificus

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
Subunit structure	The complex is composed of two ATP-binding proteins (RbsA), two transmembrane proteins (RbsC and RbsD) and a solute-binding protein (RbsB) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. [View classification] Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW monosaccharide-transporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	Ribose import ATP-binding protein RbsA		PRO_0000261119
Regions
	Domain	6 – 242	237	ABC transporter 1
	Domain	253 – 495	243	ABC transporter 2
	Nucleotide binding	38 – 45	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7MEV1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 8097D8EF3DBD7F80	FASTA	501	54,854
	10 20 30 40 50 60 MNQAILQLSE IEKAFPGVKA LDKASLNVYP GRVMALMGEN GAGKSTLMKV LTGIYSRDAG 70 80 90 100 110 120 EIVYQGQPAQ FKGPRDSQQA GISIIHQELN LIRELTIAEN IFLGREITSA FGRIDWPQMY 130 140 150 160 170 180 AEADKLLARL KVKHSSKTLL GQLSLGEQQM VEIAKALSFE SKVIIMDEPT DALTDTETEA 190 200 210 220 230 240 LFSVIRELRE QGCGIVYISH RLKEIFEICD DITVLRDGKF IGQCEVVQTD EDGLIEMMVG 250 260 270 280 290 300 RKLEEQYPRI DVVHGQTCLE VIGLTGSGVH DVSFTLKRGE ILGISGLMGA GRTELMKVIY 310 320 330 340 350 360 GALPSERGVI NLDNRTINPV SPQDGLANGI AYISEDRKGD GLVLGLSVKE NMSLCALDKL 370 380 390 400 410 420 SKGVQIQHQD EVVAVDDFIQ LFNIKTPSRE QIIGNLSGGN QQKVAIAKGL MTKPKVLILD 430 440 450 460 470 480 EPTRGVDVGA KKEIYQLINK FKAEGMSIIL VSSEMPEVLG MSDRILVMHE GRITGEFEAK 490 500 HADQEKLMAC AVGKKVSEEA A

References

[1]

"Comparative genome analysis of Vibrio vulnificus, a marine pathogen." Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F. Genome Res. 13:2577-2587(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YJ016.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000038 Genomic DNA. Translation: BAC96595.1.
RefSeq	NP_936625.1. NC_005140.1.
3D structure databases
HSSP	HSSP built from PDB template 1G6H based on UniProtKB Q58663.
ProteinModelPortal	Q7MEV1.
ModBase	Search...
Protein-protein interaction databases
STRING	196600.VVA0569.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC96595; BAC96595; BAC96595.
GeneID	2621120.
KEGG	vvy:VVA0569.
PATRIC	20174522. VBIVibVul40472_3768.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1129.
KO	K10441.
OMA	LMTRPNV.
ProtClustDB	PRK10762.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR015861. ABC_transpr_RbsA. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. PS51254. RBSA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RBSA_VIBVY

Accession

Primary (citable) accession number: Q7MEV1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	December 15, 2003
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program