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Q7MEH4 (Q7MEH4_VIBVY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981
Gene names
Ordered Locus Names:VVA0696
OrganismVibrio vulnificus (strain YJ016) [Complete proteome] [HAMAP]
Taxonomic identifier196600 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. SAAS SAAS006223 RuleBase RU003981

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981

Sequence similarities

Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
   Molecular functionAminotransferase SAAS SAAS006223 RuleBase RU003981
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycine catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular functionaminomethyltransferase activity

Inferred from electronic annotation. Source: EC

transaminase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q7MEH4 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: A0A95980BAB73D6D

FASTA38141,516
        10         20         30         40         50         60 
METKMTQEHS DQVLLKTPLH ALHIEVGAKM VPFAGYDMPV QYPLGVKKEH LHTREAAGLF 

        70         80         90        100        110        120 
DVSHMGQLRL HGAGAAAFLE SLVPVDIVDL GEGKQRYAFF TNEQGGIMDD LMVANLGDHL 

       130        140        150        160        170        180 
FVVVNAACKE QDINHLQAHI PSDVELEIID DRALLAIQGP KAVEVLSRFQ PAVAEMLFMD 

       190        200        210        220        230        240 
VQKLELLGVE CIISRSGYTG EDGYEISVPA DKAEALARAL TAEEEVEWIG LGARDSLRLE 

       250        260        270        280        290        300 
CGLCLYGHDL DETTTPVEAS LLWGIQKVRR AGGEREGGFP GADIILKQIE TKDVSRKRVG 

       310        320        330        340        350        360 
LVGQTKAPVR EGAELFDGEG NKVGVVTSGT AGPNAGKPVS MAYLRSDLTE IGTEVFAEVR 

       370        380 
GKLLPMTVEK MPFVPQRYYR G

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References

[1]"Comparative genome analysis of Vibrio vulnificus, a marine pathogen."
Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L., Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P., Lee C.-T., Hor L.-I., Tsai S.-F.
Genome Res. 13:2577-2587(2003) [PubMed: 14656965] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000038 Genomic DNA. Translation: BAC96722.1.
RefSeqNP_936752.1. NC_005140.1.

3D structure databases

ProteinModelPortalQ7MEH4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7MEH4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2622660.
GenomeReviewsGene locus VVA0696 in contig BA000038_GR.
KEGGvvy:VVA0696.
NMPDRfig|196600.1.peg.4023.
PATRIC20174772. VBIVibVul40472_3891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0404.
HOGENOMHBG299834.
OMAMPVQYPL.
PhylomeDBQ7MEH4.
ProtClustDBCLSK910129.

Enzyme and pathway databases

BioCycVVUL196600:VVA0696-MONOMER.

Family and domain databases

InterProIPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR006223. GcvT.
[Graphical view]
KOK00605.
PANTHERPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. GcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ7MEH4_VIBVY
AccessionPrimary (citable) accession number: Q7MEH4
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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