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Q7MBZ9

- UXUA_VIBVY

UniProt

Q7MBZ9 - UXUA_VIBVY

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Protein

Mannonate dehydratase

Gene

uxuA

Organism
Vibrio vulnificus (strain YJ016)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the dehydration of D-mannonate.UniRule annotation

Catalytic activityi

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.UniRule annotation

Cofactori

Fe2+UniRule annotation, Mn2+UniRule annotation

Pathwayi

GO - Molecular functioni

  1. mannonate dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. glucuronate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Iron, Manganese

Enzyme and pathway databases

BioCyciVVUL196600:GJ9W-4988-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannonate dehydrataseUniRule annotation (EC:4.2.1.8UniRule annotation)
Alternative name(s):
D-mannonate hydro-lyaseUniRule annotation
Gene namesi
Name:uxuAUniRule annotation
Ordered Locus Names:VVA1588
OrganismiVibrio vulnificus (strain YJ016)
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002675: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395Mannonate dehydratasePRO_0000170693Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi196600.VVA1588.

Structurei

3D structure databases

ProteinModelPortaliQ7MBZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannonate dehydratase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1312.
HOGENOMiHOG000195381.
KOiK01686.
OMAiIPNGQVW.
OrthoDBiEOG6ZSP6Z.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00106. UxuA.
InterProiIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFiPIRSF016049. Man_dehyd. 1 hit.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00695. uxuA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7MBZ9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQTWRWYGP NDPVSLDDIC QAGATGIVNA LHHIPNGEVW SKEEILKRKA
60 70 80 90 100
IIEEKGLTWS VVESVPVHEE IKTQTGNFQQ WIDNYKQTLR NLAECGIDTV
110 120 130 140 150
CYNFMPVLDW TRTDLEFEMP DGSKALRFDQ IAFAAFELHI LKRPGAEADY
160 170 180 190 200
SEAEQAQALE YFNNMSEAQI QQLTSNIIAG LPGAEEGYTL EEFQAQLDRY
210 220 230 240 250
AGISKDKLRE HMAYFLSQLM PVCEAHGLKL AVHPDDPPRP ILGLPRIVST
260 270 280 290 300
IEDIDWLTEK VPSKMNGLTM CTGSYGVRGD NDLVKMIKKH GERIYFTHLR
310 320 330 340 350
STKREESNPM TFHEAAHLDG DVDMYNVVMA ILDEEQRRAE VGDHRLIPMR
360 370 380 390
PDHGHQMLDD LKKKTNPGYS AIGRLKGLAE VRGLEMALKR AFYTK
Length:395
Mass (Da):44,947
Last modified:April 26, 2004 - v2
Checksum:iE144A3DD6DE67727
GO

Sequence cautioni

The sequence BAC97614.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000038 Genomic DNA. Translation: BAC97614.1. Different initiation.
RefSeqiNP_937644.1. NC_005140.1.

Genome annotation databases

EnsemblBacteriaiBAC97614; BAC97614; BAC97614.
GeneIDi2622450.
KEGGivvy:VVA1588.
PATRICi20176434. VBIVibVul40472_4718.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000038 Genomic DNA. Translation: BAC97614.1 . Different initiation.
RefSeqi NP_937644.1. NC_005140.1.

3D structure databases

ProteinModelPortali Q7MBZ9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 196600.VVA1588.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC97614 ; BAC97614 ; BAC97614 .
GeneIDi 2622450.
KEGGi vvy:VVA1588.
PATRICi 20176434. VBIVibVul40472_4718.

Phylogenomic databases

eggNOGi COG1312.
HOGENOMi HOG000195381.
KOi K01686.
OMAi IPNGQVW.
OrthoDBi EOG6ZSP6Z.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci VVUL196600:GJ9W-4988-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00106. UxuA.
InterProi IPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view ]
Pfami PF03786. UxuA. 1 hit.
[Graphical view ]
PIRSFi PIRSF016049. Man_dehyd. 1 hit.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR00695. uxuA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJ016.

Entry informationi

Entry nameiUXUA_VIBVY
AccessioniPrimary (citable) accession number: Q7MBZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: November 26, 2014
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3