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Q7MBY8

- Q7MBY8_VIBVY

UniProt

Q7MBY8 - Q7MBY8_VIBVY

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Protein
Submitted name: Dehydrogenase
Gene
VVA1599
Organism
Vibrio vulnificus (strain YJ016)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei91 – 911NADPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 184NADPImported
Nucleotide bindingi37 – 393NADPImported
Nucleotide bindingi43 – 442NADPImported
Nucleotide bindingi68 – 692NADPImported
Nucleotide bindingi158 – 1669NADPImported

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. nucleotide binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

NADPImported, Nucleotide-bindingImported

Enzyme and pathway databases

BioCyciVVUL196600:GJ9W-4999-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DehydrogenaseImported
Gene namesi
Ordered Locus Names:VVA1599Imported
OrganismiVibrio vulnificus (strain YJ016)Imported
Taxonomic identifieri196600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002675: Chromosome II

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-8298803,EBI-8298803

Protein-protein interaction databases

MINTiMINT-8408766.
STRINGi196600.VVA1599.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UCEX-ray1.80A/B/C/D1-223[»]
3UCFX-ray2.35A/B/C/D1-223[»]
ProteinModelPortaliQ7MBY8.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1028.
OMAiRKVVANT.
OrthoDBiEOG679TBX.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PRINTSiPR00081. GDHRDH.

Sequencei

Sequence statusi: Complete.

Q7MBY8-1 [UniParc]FASTAAdd to Basket

« Hide

MMGSDKTVYV VLGGTSGIGA ELAKQLESEH TIVHVASRQT GLDISDEKSV    50
YHYFETIGAF DHLIVTAGSY APAGKVVDVE VTQAKYAFDT KFWGAVLAAK 100
HGARYLKQGG SITLTSGMLS RKVVANTYVK AAINAAIEAT TKVLAKELAP 150
IRVNAISPGL TKTEAYKGMN ADDRDAMYQR TQSHLPVGKV GEASDIAMAY 200
LFAIQNSYMT GTVIDVDGGA LLG 223
Length:223
Mass (Da):23,654
Last modified:December 15, 2003 - v1
Checksum:iCBD4EEFF037FAD09
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000038 Genomic DNA. Translation: BAC97625.1.
RefSeqiNP_937655.1. NC_005140.1.

Genome annotation databases

EnsemblBacteriaiBAC97625; BAC97625; BAC97625.
GeneIDi2622461.
KEGGivvy:VVA1599.
PATRICi20176456. VBIVibVul40472_4729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000038 Genomic DNA. Translation: BAC97625.1 .
RefSeqi NP_937655.1. NC_005140.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3UCE X-ray 1.80 A/B/C/D 1-223 [» ]
3UCF X-ray 2.35 A/B/C/D 1-223 [» ]
ProteinModelPortali Q7MBY8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-8408766.
STRINGi 196600.VVA1599.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC97625 ; BAC97625 ; BAC97625 .
GeneIDi 2622461.
KEGGi vvy:VVA1599.
PATRICi 20176456. VBIVibVul40472_4729.

Phylogenomic databases

eggNOGi COG1028.
OMAi RKVVANT.
OrthoDBi EOG679TBX.

Enzyme and pathway databases

BioCyci VVUL196600:GJ9W-4999-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PRINTSi PR00081. GDHRDH.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YJ016Imported.
  2. "Structural and biochemical characterization of an atypical short-chain dehydrogenase/reductase reveals an unusual cofactor preference."
    Buysschaert G., Verstraete K., Savvides S.N., Vergauwen B.
    FEBS J. 280:1358-1370(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiQ7MBY8_VIBVY
AccessioniPrimary (citable) accession number: Q7MBY8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: June 11, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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