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Q7MAK6 (SYR_WOLSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:WS0186
OrganismWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes) [Complete proteome] [HAMAP]
Taxonomic identifier273121 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeWolinella

Protein attributes

Sequence length528 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 528528Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242122

Regions

Motif112 – 12211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q7MAK6 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: C9136A66832E3FD7

FASTA52859,256
        10         20         30         40         50         60 
MHHTIKHLLE TTLGFSVVLE KPKDKNHGHY ATPAAFSLAK ELKKNPALIA QELSKKLSEI 

        70         80         90        100        110        120 
EVFESVQSVG GYINFRLKQG FLDAQASLAL SQGREFGKGD KQGSILLEYV SANPTGPLHI 

       130        140        150        160        170        180 
GHARGAVLGD ALSRIGRHLG YALETEYYVN DAGNQIHLLG LSIYLAGRDS LLSLPVTYPE 

       190        200        210        220        230        240 
QYYRGEYIVD IAKEALKKWG EKAFADEAFI PELSLFGKEL MLEEIRSNLA DTHIHFDHYV 

       250        260        270        280        290        300 
SEKSLYPRWE ETYALLQSHQ GCYEGGGKVW LRSSAHGDEK DRVIVRESGE PTYLAGDIIY 

       310        320        330        340        350        360 
HADKFARPYD RYINIWGADH HGYIARVKAA IEFLGHDSSK LEVLLSQMVT LLKGGQPYKM 

       370        380        390        400        410        420 
SKRAGNFILM RDVLEDIGAD ALRFIFLSKK PDTHLEFDVD DLNKEDSSNP IFYINYAHAR 

       430        440        450        460        470        480 
IHTMLGKSSL DSQEIEAASL EGLEDSIFDL LFLSLQLPQV LEDSFENRAI QKVAEYLRAL 

       490        500        510        520 
AGEFHKFYNE HKILETPQEA ALLKVCKVVA LSLSQGLALL GITAKERM 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571657 Genomic DNA. Translation: CAE09347.1.
RefSeqNP_906447.1. NC_005090.1.

3D structure databases

ProteinModelPortalQ7MAK6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273121.WS0186.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE09347; CAE09347; WS0186.
GeneID2555143.
KEGGwsu:WS0186.
PATRIC24037480. VBIWolSuc63014_0182.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_WOLSU
AccessionPrimary (citable) accession number: Q7MAK6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 15, 2003
Last modified: April 16, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries