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Q7MAK6

- SYR_WOLSU

UniProt

Q7MAK6 - SYR_WOLSU

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:WS0186
OrganismiWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
Taxonomic identifieri273121 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeWolinella
ProteomesiUP000000422: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 528528Arginine--tRNA ligasePRO_0000242122Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi273121.WS0186.

Structurei

3D structure databases

ProteinModelPortaliQ7MAK6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi112 – 12211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiPRVKGAI.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7MAK6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHHTIKHLLE TTLGFSVVLE KPKDKNHGHY ATPAAFSLAK ELKKNPALIA
60 70 80 90 100
QELSKKLSEI EVFESVQSVG GYINFRLKQG FLDAQASLAL SQGREFGKGD
110 120 130 140 150
KQGSILLEYV SANPTGPLHI GHARGAVLGD ALSRIGRHLG YALETEYYVN
160 170 180 190 200
DAGNQIHLLG LSIYLAGRDS LLSLPVTYPE QYYRGEYIVD IAKEALKKWG
210 220 230 240 250
EKAFADEAFI PELSLFGKEL MLEEIRSNLA DTHIHFDHYV SEKSLYPRWE
260 270 280 290 300
ETYALLQSHQ GCYEGGGKVW LRSSAHGDEK DRVIVRESGE PTYLAGDIIY
310 320 330 340 350
HADKFARPYD RYINIWGADH HGYIARVKAA IEFLGHDSSK LEVLLSQMVT
360 370 380 390 400
LLKGGQPYKM SKRAGNFILM RDVLEDIGAD ALRFIFLSKK PDTHLEFDVD
410 420 430 440 450
DLNKEDSSNP IFYINYAHAR IHTMLGKSSL DSQEIEAASL EGLEDSIFDL
460 470 480 490 500
LFLSLQLPQV LEDSFENRAI QKVAEYLRAL AGEFHKFYNE HKILETPQEA
510 520
ALLKVCKVVA LSLSQGLALL GITAKERM
Length:528
Mass (Da):59,256
Last modified:December 15, 2003 - v1
Checksum:iC9136A66832E3FD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571657 Genomic DNA. Translation: CAE09347.1.
RefSeqiNP_906447.1. NC_005090.1.
WP_011138147.1. NC_005090.1.

Genome annotation databases

EnsemblBacteriaiCAE09347; CAE09347; WS0186.
GeneIDi2555143.
KEGGiwsu:WS0186.
PATRICi24037480. VBIWolSuc63014_0182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571657 Genomic DNA. Translation: CAE09347.1 .
RefSeqi NP_906447.1. NC_005090.1.
WP_011138147.1. NC_005090.1.

3D structure databases

ProteinModelPortali Q7MAK6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273121.WS0186.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE09347 ; CAE09347 ; WS0186 .
GeneIDi 2555143.
KEGGi wsu:WS0186.
PATRICi 24037480. VBIWolSuc63014_0182.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi PRVKGAI.
OrthoDBi EOG6JB13C.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W.

Entry informationi

Entry nameiSYR_WOLSU
AccessioniPrimary (citable) accession number: Q7MAK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 15, 2003
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3