Q7M9N3 (Q7M9N3_WOLSU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LIPID A DISACCHARIDE SYNTHASE EMBL CAE09911.1
EC=2.4.1.182 EMBL CAE09911.1

Gene names

Name:	lpxB EMBL CAE09911.1
Ordered Locus Names:	WS0798

Organism

Wolinella succinogenes [Complete proteome] [HAMAP]

Taxonomic identifier

844 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Wolinella

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL CAE09911.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7M9N3 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 046CB6ED85293078	FASTA	356	40,222
	10 20 30 40 50 60 MKLLVSALEP SSNLHLASLM KHLEGKVELM GIFDSKLSTK PPLYTPDQFS VMGFLDVIER 70 80 90 100 110 120 LGFFWRAKKE MAHLASEADK ILLMDSSSFN IPLAKAIKKA FPSKEIIYYI LPQVWAWKPW 130 140 150 160 170 180 RAKAIEESCD FLAAILPFET ACYQSKAEYV GHPLLDLLPP IRTSLPKEER IAFMPGSRKG 190 200 210 220 230 240 EIGRLFPVFR EVARRIEAPK TLVIPSIYEG ASLEEIYGDL EGFELSYDAP KTLLESSFAF 250 260 270 280 290 300 ICSGTATLEA ALLGIPLVLA YKARPLDYFI AKNLVKIEHI GLANIFETRR GEEPLHEELL 310 320 330 340 350 QEGVNVEALL EAYWRCDKEH FVERAKALRG YLRKGSSLRV AQRILEIDSK VIFNDG

References

[1]

"Complete genome sequence and analysis of Wolinella succinogenes." Baar C., Eppinger M., Raddatz G., Simon J., Lanz C., Klimmek O., Nandakumar R., Gross R., Rosinus A., Keller H., Jagtap P., Linke B., Meyer F., Lederer H., Schuster S.C. Proc. Natl. Acad. Sci. U.S.A. 100:11690-11695(2003) [PubMed: 14500908] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSMZ 1740.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX571659 Genomic DNA. Translation: CAE09911.1.
RefSeq	NP_907011.1. NC_005090.1.
3D structure databases
ProteinModelPortal	Q7M9N3.
ModBase	Search...
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2554419.
GenomeReviews	Gene locus WS0798 in contig BX571656_GR.
KEGG	wsu:WS0798.
NMPDR	fig|273121.1.peg.738.
PATRIC	24038646. VBIWolSuc63014_0753.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	HEEFIQE.
ProtClustDB	PRK14089.
Enzyme and pathway databases
BioCyc	WSUC273121:WS0798-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7M9N3_WOLSU

Accession

Primary (citable) accession number: Q7M9N3

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)