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Q7M9I4

- PNP_WOLSU

UniProt

Q7M9I4 - PNP_WOLSU

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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi518 – 5181MagnesiumUniRule annotation
Metal bindingi524 – 5241MagnesiumUniRule annotation

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
  4. RNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:WS0899
OrganismiWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
Taxonomic identifieri273121 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeWolinella
ProteomesiUP000000422: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 736736Polyribonucleotide nucleotidyltransferasePRO_0000329937Add
BLAST

Proteomic databases

PRIDEiQ7M9I4.

Interactioni

Protein-protein interaction databases

STRINGi273121.WS0899.

Structurei

3D structure databases

ProteinModelPortaliQ7M9I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini584 – 64461KHUniRule annotationAdd
BLAST
Domaini665 – 73268S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
Contains 1 KH domain.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiHGNFKSN.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7M9I4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNATIKEIAL PNKTETFEFG AIAKQANGSV LYRCGKSVLL ASVCYESDER
60 70 80 90 100
VKEDFLPLTV QYIEKSYAAG KFPGGFIKRE SKPGDFETLT SRIIDRSLRP
110 120 130 140 150
LFPKGYAHPT QITVMVLSAQ NDADLQTMAL NAASAALFVS DIPLRKPVHG
160 170 180 190 200
LRIGKINGAL VVNPTTKEMS ESTLDLFVSG VEEDLLMIEM RTLASDEINN
210 220 230 240 250
TCFVGDCGMV AASASDILKI HQANEMKEEE LLEALELAKT SIKKASACYV
260 270 280 290 300
EAFTPLAKPD AILELKPDIT SSEIYQYIKE NHAIAIKEAI TRMAKSERHS
310 320 330 340 350
DLKRIAKEIA SSERAQESEW SFEAVYETVG KYKREAVRAL ILEERRRADG
360 370 380 390 400
RGLKEVRPID IQTNILPNAH ASALFTRGET QALVVATLGG DMDAQSYELL
410 420 430 440 450
TEKGSSKERF MVHYNFPSFS VGEAGMVGAP GRRELGHGNL AKRALEPTIE
460 470 480 490 500
EWGAQTIRLV SEILESNGSS SMATVCGGSL ALKAAGINTT ALVAGVAMGL
510 520 530 540 550
IVEAEKHAIL TDIMGLEDHD GDMDFKIAGT STGITAMQMD IKLGGLSMEI
560 570 580 590 600
LKEALYQAKE GREHILGIME KAQSEIIIND EILPSLQIFS INPGRIVDII
610 620 630 640 650
GQAGKTIKEI IERFEVAIDL NRDNGEVKVT GSNKQKVEAA KEHILSISNQ
660 670 680 690 700
EAPQRVRVAD VYSAGEVFKG KVKKIVDFGA FIELPKGGDG LLHVSKIVQH
710 720 730
RDQRIDEVIK EGEEIEVQIL SINKNKVELG RATRPN
Length:736
Mass (Da):80,526
Last modified:December 15, 2003 - v1
Checksum:i96BC12E4FA63C1A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571659 Genomic DNA. Translation: CAE10004.1.
RefSeqiNP_907104.1. NC_005090.1.
WP_011138801.1. NC_005090.1.

Genome annotation databases

EnsemblBacteriaiCAE10004; CAE10004; WS0899.
GeneIDi2555106.
KEGGiwsu:WS0899.
PATRICi24038838. VBIWolSuc63014_0847.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571659 Genomic DNA. Translation: CAE10004.1 .
RefSeqi NP_907104.1. NC_005090.1.
WP_011138801.1. NC_005090.1.

3D structure databases

ProteinModelPortali Q7M9I4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273121.WS0899.

Proteomic databases

PRIDEi Q7M9I4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE10004 ; CAE10004 ; WS0899 .
GeneIDi 2555106.
KEGGi wsu:WS0899.
PATRICi 24038838. VBIWolSuc63014_0847.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi HGNFKSN.
OrthoDBi EOG6WT8CC.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W.

Entry informationi

Entry nameiPNP_WOLSU
AccessioniPrimary (citable) accession number: Q7M9I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 15, 2003
Last modified: November 26, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3