Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q7M8Z9 (UPPP_WOLSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:WS1290
OrganismWolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes) [Complete proteome] [HAMAP]
Taxonomic identifier273121 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeWolinella

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151240

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane69 – 8921Helical; Potential
Transmembrane96 – 11621Helical; Potential
Transmembrane172 – 19221Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane233 – 25321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q7M8Z9 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 8AC5451D7B34CC59

FASTA25628,163
        10         20         30         40         50         60 
MDIFHAIILG IVEGLTEFLP VSSTGHLILV SELLGIKQDD FHKTFEISIQ LGSILAVLAL 

        70         80         90        100        110        120 
FRERLFSGVD IWLKLAVAFI PTGALGFLLY KHVKALFAPS TVAYALILGG IVFLVLEWLH 

       130        140        150        160        170        180 
KDKEYKINSV ESIGYKEALA IGFFQALAMI PGTSRSGSTI VGGLILGLNR KVAAEFSFLL 

       190        200        210        220        230        240 
ALPTMFIATG YDLYKNSHTL SIENLSALGV GFVVAFIFAM IAVKGFLKFI SRFNFVPFGI 

       250 
YRIILGIIFL FYLDLI 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX571660 Genomic DNA. Translation: CAE10368.1.
RefSeqNP_907468.1. NC_005090.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273121.WS1290.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE10368; CAE10368; WS1290.
GeneID2554216.
KEGGwsu:WS1290.
PATRIC24039596. VBIWolSuc63014_1216.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAVIYFRNE.
OrthoDBEOG6QP13M.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_WOLSU
AccessionPrimary (citable) accession number: Q7M8Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: December 15, 2003
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families