ID   Q7M8J2_WOLSU            Unreviewed;       713 AA.
AC   Q7M8J2;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=ADENYLATE CYCLASE {ECO:0000313|EMBL:CAE10664.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAE10664.1};
GN   Name=gidA {ECO:0000313|EMBL:CAE10664.1};
GN   OrderedLocusNames=WS1633 {ECO:0000313|EMBL:CAE10664.1};
OS   Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 /
OS   NCTC 11488 / FDC 602W) (Vibrio succinogenes).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Wolinella.
OX   NCBI_TaxID=273121 {ECO:0000313|Proteomes:UP000000422};
RN   [1] {ECO:0000313|EMBL:CAE10664.1, ECO:0000313|Proteomes:UP000000422}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 /
RC   NCTC 11488 / FDC 602W {ECO:0000313|Proteomes:UP000000422};
RX   PubMed=14500908; DOI=10.1073/pnas.1932838100;
RA   Baar C., Eppinger M., Raddatz G., Simon JM., Lanz C., Klimmek O.,
RA   Nandakumar R., Gross R., Rosinus A., Keller H., Jagtap P., Linke B.,
RA   Meyer F., Lederer H., Schuster S.C.;
RT   "Complete genome sequence and analysis of Wolinella succinogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:11690-11695(2003).
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DR   EMBL; BX571661; CAE10664.1; -; Genomic_DNA.
DR   RefSeq; WP_011139448.1; NC_005090.1.
DR   AlphaFoldDB; Q7M8J2; -.
DR   STRING; 273121.WS1633; -.
DR   KEGG; wsu:WS1633; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_7; -.
DR   Proteomes; UP000000422; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAE10664.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000422};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        368..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          459..592
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   713 AA;  79444 MW;  0DA8A053EA3EAA1D CRC64;
     MSRSNLLGIL LVAILGLEGF LYFKPIPLLL SLEHKIKDAM FWWRGERAGN PNILIIDIDE
     KSLQALGQWP WSRDKVAVIL NNLTQSGAGI IGLDVVFAEE DASSPVKILQ SLGIDSSGLV
     DYDTLLAQTL ESSPVVAGYV FAMQEDGVTP HGSPASRAIV IEREKPEHSY LPKPYRAILN
     IPLLQQSAYS SGYFNTLPDE DGVVRSVPLL MEYEGILYPA LSLEMIRLAL GVGRIEVEYF
     EQGVQAVRLG DILIPTDAFG RMRLNYTGGA KNYPYLSALD VYKGEFEREQ VEGKLLLLGT
     SSAGLLDLRS TPFESVFPGV EVHANALDNL LSGDFIAKPL WSMGADVTLL LLLPLAGWLI
     LRLFGVLLSF LGMTLLLWVL FGGHYYLMFS QGVILHTLTP LIATLSLFFG GIMINYFFES
     RQKELIKAKF ARKVSKAVVE ELTKNPSALS LEGKEAEITI FFSDVRDFTS ISESLPSPQA
     LIDLLNDYMT PMVEIITRHQ GTIDKFIGDA VMAYWNAPKA VPFHADEALL SSIEQIEELT
     PLNEKLQNQG RPLIRIGIGL NSGKCIVGEM GSLGRSDYTC IGDPVNLASR IEGLCKGYGA
     LILLSEYTLA LLQNPNRYAL REIDFVRVKG KEKPVRIYEC LGFKERPWKE NPSQFAEALA
     LYRQGRFKEA LEVFEKLKAQ NPEKLFSLYT ERCEHYLNEP PKDFDGVFAY KTK
//