Q7M6Y3 (PICA_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphatidylinositol-binding clathrin assembly protein

Alternative name(s):
Clathrin assembly lymphoid myeloid leukemia
Short name=CALM

Gene names

Name:	Picalm
Synonyms:	Calm, Fit1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	660 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Plays a crucial role in fetal and adult hematopoiesis, and normal prenatal and postnatal growth and viability. Ref.1 Ref.4
Subunit structure	Binds clathrin and phosphatidylinositol 4,5-bisphosphate By similarity.
Subcellular location	Membrane › clathrin-coated pit By similarity. Golgi apparatus By similarity. Cytoplasmic vesicle › clathrin-coated vesicle By similarity. Note: Colocalized with clathrin in the Golgi area By similarity.
Tissue specificity	Skins and livers of 1-week-old mice. Ref.1
Sequence similarities	Contains 1 ENTH (epsin N-terminal homology) domain.
Sequence caution	The sequence BAC39454.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Endocytosis
Cellular component	Coated pit Cytoplasmic vesicle Golgi apparatus Membrane
Coding sequence diversity	Alternative splicing
Molecular function	Developmental protein
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	axonogenesis Inferred from mutant phenotype PubMed 18842885. Source: BHF-UCL clathrin coat assembly Inferred from electronic annotation. Source: InterPro dendrite morphogenesis Inferred from mutant phenotype PubMed 18842885. Source: BHF-UCL endosomal transport Inferred from electronic annotation. Source: Compara hemopoiesis Inferred from mutant phenotype Ref.1. Source: UniProtKB negative regulation of receptor-mediated endocytosis Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara receptor internalization Inferred from electronic annotation. Source: Compara receptor-mediated endocytosis Inferred from direct assay Ref.1. Source: UniProtKB regulation of protein localization Inferred from electronic annotation. Source: Compara
Cellular_component	AP-2 adaptor complex Inferred from electronic annotation. Source: Compara Golgi apparatus Inferred from electronic annotation. Source: UniProtKB-SubCell coated pit Inferred from direct assay Ref.1. Source: UniProtKB intracellular Inferred from direct assay PubMed 18842885. Source: BHF-UCL nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	1-phosphatidylinositol binding Inferred from sequence or structural similarity. Source: UniProtKB clathrin binding Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q7M6Y3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q7M6Y3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     420-469: Missing.
     506-510: Missing.
     594-601: Missing.

Isoform 3 (identifier: Q7M6Y3-3)

The sequence of this isoform differs from the canonical sequence as follows:
     420-469: Missing.
     506-510: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q7M6Y3-4)

The sequence of this isoform differs from the canonical sequence as follows:
     420-469: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q7M6Y3-5)

The sequence of this isoform differs from the canonical sequence as follows:
     506-510: Missing.

Isoform 6 (identifier: Q7M6Y3-6)

The sequence of this isoform differs from the canonical sequence as follows:
     594-601: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 660	660	Phosphatidylinositol-binding clathrin assembly protein		PRO_0000187063
Regions
	Domain	14 – 145	132	ENTH
Amino acid modifications
	Modified residue	443	1	Phosphoserine Ref.5
Natural variations
	Alternative sequence	420 – 469	50	Missing in isoform 2, isoform 3 and isoform 4.		VSP_050684
	Alternative sequence	506 – 510	5	Missing in isoform 2, isoform 3 and isoform 5.		VSP_050685
	Alternative sequence	594 – 601	8	Missing in isoform 2 and isoform 6.		VSP_050686
Experimental info
	Sequence conflict	522	1	N → S in AAH21491. Ref.2
	Sequence conflict	522	1	N → S in AAH23843. Ref.2
	Sequence conflict	522	1	N → S in AAH25566. Ref.2
	Sequence conflict	522	1	N → S in AAH57683. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 7FB206508281BCDF	FASTA	660	71,543
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD 430 440 450 460 470 480 PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH 490 500 510 520 530 540 SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL 550 560 570 580 590 600 DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ 610 620 630 640 650 660 YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG PVSGAQIQFM
	Isoform 2 [UniParc]. Checksum: 825D7F7B7154DD8A	FASTA	597	64,648
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGG 430 440 450 460 470 480 FSPSPVAQPH SSAGLNVDFE SVFGNKSTNV AVDSGGGLLK PTVASQNQSL PVAKLPPNKL 490 500 510 520 530 540 VSDDLDSSLA NLVGNLGIGN GTTKNDVSWS QPGEKKLTGG SNWQPKVAPT TAWSAATMAP 550 560 570 580 590 PVMAYPATTP TGMIGYGIPP QMGSVPVMTQ PTLIYSQPVM RPPNPFGPVS GAQIQFM
	Isoform 3 [UniParc]. Checksum: C365144C975C2B50	FASTA	605	65,623
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGG 430 440 450 460 470 480 FSPSPVAQPH SSAGLNVDFE SVFGNKSTNV AVDSGGGLLK PTVASQNQSL PVAKLPPNKL 490 500 510 520 530 540 VSDDLDSSLA NLVGNLGIGN GTTKNDVSWS QPGEKKLTGG SNWQPKVAPT TAWSAATMNG 550 560 570 580 590 600 MHFPQYAPPV MAYPATTPTG MIGYGIPPQM GSVPVMTQPT LIYSQPVMRP PNPFGPVSGA QIQFM
	Isoform 4 [UniParc]. Checksum: 86E8189B6C05F005	FASTA	610	66,184
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGG 430 440 450 460 470 480 FSPSPVAQPH SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL 490 500 510 520 530 540 PPNKLVSDDL DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA 550 560 570 580 590 600 ATMNGMHFPQ YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG 610 PVSGAQIQFM
	Isoform 5 [UniParc]. Checksum: F729CEF5D3D82781	FASTA	655	70,982
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD 430 440 450 460 470 480 PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH 490 500 510 520 530 540 SSAGLNVDFE SVFGNKSTNV AVDSGGGLLK PTVASQNQSL PVAKLPPNKL VSDDLDSSLA 550 560 570 580 590 600 NLVGNLGIGN GTTKNDVSWS QPGEKKLTGG SNWQPKVAPT TAWSAATMNG MHFPQYAPPV 610 620 630 640 650 MAYPATTPTG MIGYGIPPQM GSVPVMTQPT LIYSQPVMRP PNPFGPVSGA QIQFM
	Isoform 6 [UniParc]. Checksum: 0CEEEEA9225CC446	FASTA	652	70,568
	10 20 30 40 50 60 MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 70 80 90 100 110 120 DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 130 140 150 160 170 180 STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 190 200 210 220 230 240 FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 250 260 270 280 290 300 LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 310 320 330 340 350 360 TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 370 380 390 400 410 420 VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQGASTWGD 430 440 450 460 470 480 PFSATLDAVE DAIPSLNPFL TKSSGDVHLP IASDVSTFTT RTPTHEMFVG FSPSPVAQPH 490 500 510 520 530 540 SSAGLNVDFE SVFGNKSTNV AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL 550 560 570 580 590 600 DSSLANLVGN LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMAPPVMAY 610 620 630 640 650 PATTPTGMIG YGIPPQMGSV PVMTQPTLIY SQPVMRPPNP FGPVSGAQIQ FM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice." Klebig M.L., Wall M.D., Potter M.D., Rowe E.L., Carpenter D.A., Rinchik E.M. Proc. Natl. Acad. Sci. U.S.A. 100:8360-8365(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY. Strain: BALB/cRl. Tissue: Liver.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3; 4; 5 AND 6). Strain: Czech II and FVB/N. Tissue: Mammary tumor and Retina.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 143-660 (ISOFORM 2). Strain: C57BL/6J. Tissue: Epididymis and Kidney.
[4]	"Mutations in the murine fitness 1 gene result in defective hematopoiesis." Potter M.D., Shinpock S.G., Popp R.A., Godfrey V., Carpenter D.A., Bernstein A., Johnson D.K., Rinchik E.M. Blood 90:1850-1857(1997) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[5]	"Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-443, MASS SPECTROMETRY. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY206701 mRNA. Translation: AAO17153.1. BK001028 mRNA. Translation: DAA01470.1. BC011470 mRNA. Translation: AAH11470.1. BC021491 mRNA. Translation: AAH21491.1. BC023843 mRNA. Translation: AAH23843.1. BC025566 mRNA. Translation: AAH25566.1. BC027116 mRNA. Translation: AAH27116.1. BC057683 mRNA. Translation: AAH57683.1. AK085472 mRNA. Translation: BAC39454.2. Different initiation. AK162360 mRNA. Translation: BAE36872.1.
IPI	IPI00264501. IPI00321378. IPI00404434. IPI00404435. IPI00404436. IPI00404438.
RefSeq	NP_001239449.1. NM_001252520.1. NP_001239450.1. NM_001252521.1. NP_001239451.1. NM_001252522.1. NP_001239452.1. NM_001252523.1. NP_001239453.1. NM_001252524.1. NP_666306.2. NM_146194.4.
UniGene	Mm.235175. Mm.393563. Mm.394497.
3D structure databases
ProteinModelPortal	Q7M6Y3.
SMR	Q7M6Y3. Positions 20-288.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q7M6Y3. 1 interaction.
STRING	10090.ENSMUSP00000051092.
PTM databases
PhosphoSite	Q7M6Y3.
Proteomic databases
PaxDb	Q7M6Y3.
PRIDE	Q7M6Y3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000049537; ENSMUSP00000051092; ENSMUSG00000039361.
GeneID	233489.
KEGG	mmu:233489.
UCSC	uc009igq.1. mouse. uc009igr.1. mouse. uc009igs.1. mouse. uc009igt.1. mouse. uc009igu.1. mouse.
Organism-specific databases
CTD	8301.
MGI	MGI:2385902. Picalm.
Phylogenomic databases
eggNOG	NOG267212.
GeneTree	ENSGT00390000008805.
HOVERGEN	HBG049391.
InParanoid	Q7M6Y3.
OMA	WNAATMA.
OrthoDB	EOG4C87RV.
Gene expression databases
Bgee	Q7M6Y3.
Genevestigator	Q7M6Y3.
Family and domain databases
Gene3D	1.20.58.150. 1 hit. 1.25.40.90. 1 hit.
InterPro	IPR011417. ANTH_dom. IPR014712. Clathrin_Pinositid-bd_GAT-like. IPR008942. ENTH_VHS. IPR013809. Epsin-like_N. [Graphical view]
Pfam	PF07651. ANTH. 1 hit. [Graphical view]
SMART	SM00273. ENTH. 1 hit. [Graphical view]
SUPFAM	SSF48464. ENTH_VHS. 1 hit.
PROSITE	PS50942. ENTH. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PICALM. mouse.
NextBio	381725.
SOURCE	Search...

Entry information

Entry name

PICA_MOUSE

Accession

Primary (citable) accession number: Q7M6Y3
Secondary accession number(s): Q3TS04 , Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2004
Last sequence update:	December 15, 2003
Last modified:	May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program