Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q7M6Y3

- PICAL_MOUSE

UniProt

Q7M6Y3 - PICAL_MOUSE

Protein

Phosphatidylinositol-binding clathrin assembly protein

Gene

Picalm

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Plays a crucial role in fetal and adult hematopoiesis, and normal prenatal and postnatal growth and viability.2 Publications

    GO - Molecular functioni

    1. 1-phosphatidylinositol binding Source: UniProtKB
    2. clathrin adaptor activity Source: Alzheimers_University_of_Toronto
    3. clathrin binding Source: UniProtKB

    GO - Biological processi

    1. axonogenesis Source: BHF-UCL
    2. cargo loading into vesicle Source: Alzheimers_University_of_Toronto
    3. cell proliferation Source: Alzheimers_University_of_Toronto
    4. clathrin coat assembly Source: InterPro
    5. clathrin-mediated endocytosis Source: Alzheimers_University_of_Toronto
    6. dendrite morphogenesis Source: BHF-UCL
    7. endosomal transport Source: Ensembl
    8. hemopoiesis Source: UniProtKB
    9. iron ion homeostasis Source: Alzheimers_University_of_Toronto
    10. iron ion import into cell Source: Alzheimers_University_of_Toronto
    11. negative regulation of gene expression Source: Alzheimers_University_of_Toronto
    12. negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
    13. negative regulation of receptor-mediated endocytosis Source: Ensembl
    14. positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
    15. positive regulation of beta-amyloid formation Source: Alzheimers_University_of_Toronto
    16. positive regulation of neuron death Source: Alzheimers_University_of_Toronto
    17. positive regulation of transcription, DNA-templated Source: Ensembl
    18. receptor internalization Source: Ensembl
    19. receptor-mediated endocytosis Source: UniProtKB
    20. regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Source: Alzheimers_University_of_Toronto
    21. regulation of protein localization Source: Ensembl
    22. synaptic vesicle maturation Source: Alzheimers_University_of_Toronto

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Endocytosis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylinositol-binding clathrin assembly protein
    Alternative name(s):
    Clathrin assembly lymphoid myeloid leukemia
    Short name:
    CALM
    Gene namesi
    Name:Picalm
    Synonyms:Calm, Fit1
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:2385902. Picalm.

    Subcellular locationi

    Membraneclathrin-coated pit By similarity. Golgi apparatus By similarity. Cytoplasmic vesicleclathrin-coated vesicle By similarity. Nucleus By similarity
    Note: Colocalized with clathrin in the Golgi area. Interaction with FAM64A may target PICALM to the nucleus in some cells.By similarity

    GO - Cellular componenti

    1. AP-2 adaptor complex Source: Ensembl
    2. coated pit Source: UniProtKB
    3. Golgi apparatus Source: UniProtKB-SubCell
    4. intracellular Source: BHF-UCL
    5. neurofibrillary tangle Source: Alzheimers_University_of_Toronto
    6. neuronal cell body Source: Alzheimers_University_of_Toronto
    7. nucleus Source: UniProtKB-SubCell
    8. vesicle Source: Alzheimers_University_of_Toronto

    Keywords - Cellular componenti

    Coated pit, Cytoplasmic vesicle, Golgi apparatus, Membrane, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 660659Phosphatidylinositol-binding clathrin assembly proteinPRO_0000187063Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ7M6Y3.
    PaxDbiQ7M6Y3.
    PRIDEiQ7M6Y3.

    PTM databases

    PhosphoSiteiQ7M6Y3.

    Expressioni

    Tissue specificityi

    Skins and livers of 1-week-old mice.1 Publication

    Gene expression databases

    BgeeiQ7M6Y3.
    GenevestigatoriQ7M6Y3.

    Interactioni

    Subunit structurei

    Binds clathrin and phosphatidylinositol 4,5-bisphosphate. Interacts with FAM64A; this interaction may change the subcellular location into the nucleus.By similarity

    Protein-protein interaction databases

    BioGridi231417. 2 interactions.
    IntActiQ7M6Y3. 3 interactions.
    MINTiMINT-1850199.
    STRINGi10090.ENSMUSP00000051092.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7M6Y3.
    SMRiQ7M6Y3. Positions 20-288.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini14 – 145132ENTHCuratedPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni221 – 29474Interaction with FAM64ABy similarityAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PICALM/SNAP91 family.Curated
    Contains 1 ENTH (epsin N-terminal homology) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG267212.
    GeneTreeiENSGT00390000008805.
    HOVERGENiHBG049391.
    InParanoidiQ7M6Y3.
    OMAiWNAATMA.
    OrthoDBiEOG76QFM8.
    PhylomeDBiQ7M6Y3.
    TreeFamiTF314861.

    Family and domain databases

    Gene3Di1.20.58.150. 1 hit.
    1.25.40.90. 1 hit.
    InterProiIPR011417. ANTH_dom.
    IPR014712. Clathrin_Pinositid-bd_GAT-like.
    IPR008942. ENTH_VHS.
    IPR013809. Epsin-like_N.
    [Graphical view]
    PfamiPF07651. ANTH. 1 hit.
    [Graphical view]
    SMARTiSM00273. ENTH. 1 hit.
    [Graphical view]
    SUPFAMiSSF48464. SSF48464. 1 hit.
    PROSITEiPS50942. ENTH. 1 hit.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Isoform 1Curated (identifier: Q7M6Y3-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN    50
    EMNVNIPQLA DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR 100
    NTLFNLSNFL DKSGLQGYDM STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR 150
    GADGVMRTMN TEKLLKTVPI IQNQMDALLD FNVNSNELTN GVINAAFMLL 200
    FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF LTRMTRISEF 250
    LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 300
    TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP 350
    HTSLTTAASP VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT 400
    FHPSVHAMSA APQGASTWGD PFSATLDAVE DAIPSLNPFL TKSSGDVHLP 450
    IASDVSTFTT RTPTHEMFVG FSPSPVAQPH SSAGLNVDFE SVFGNKSTNV 500
    AVDSGGFDEL GGLLKPTVAS QNQSLPVAKL PPNKLVSDDL DSSLANLVGN 550
    LGIGNGTTKN DVSWSQPGEK KLTGGSNWQP KVAPTTAWSA ATMNGMHFPQ 600
    YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG 650
    PVSGAQIQFM 660
    Length:660
    Mass (Da):71,543
    Last modified:December 15, 2003 - v1
    Checksum:i7FB206508281BCDF
    GO
    Isoform 2Curated (identifier: Q7M6Y3-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         420-469: Missing.
         506-510: Missing.
         594-601: Missing.

    Show »
    Length:597
    Mass (Da):64,648
    Checksum:i825D7F7B7154DD8A
    GO
    Isoform 3Curated (identifier: Q7M6Y3-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         420-469: Missing.
         506-510: Missing.

    Note: No experimental confirmation available.Curated

    Show »
    Length:605
    Mass (Da):65,623
    Checksum:iC365144C975C2B50
    GO
    Isoform 4Curated (identifier: Q7M6Y3-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         420-469: Missing.

    Note: No experimental confirmation available.Curated

    Show »
    Length:610
    Mass (Da):66,184
    Checksum:i86E8189B6C05F005
    GO
    Isoform 5Curated (identifier: Q7M6Y3-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         506-510: Missing.

    Show »
    Length:655
    Mass (Da):70,982
    Checksum:iF729CEF5D3D82781
    GO
    Isoform 6Curated (identifier: Q7M6Y3-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         594-601: Missing.

    Note: No experimental confirmation available.Curated

    Show »
    Length:652
    Mass (Da):70,568
    Checksum:i0CEEEEA9225CC446
    GO

    Sequence cautioni

    The sequence BAC39454.2 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti522 – 5221N → S in AAH21491. (PubMed:15489334)Curated
    Sequence conflicti522 – 5221N → S in AAH23843. (PubMed:15489334)Curated
    Sequence conflicti522 – 5221N → S in AAH25566. (PubMed:15489334)Curated
    Sequence conflicti522 – 5221N → S in AAH57683. (PubMed:15489334)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei420 – 46950Missing in isoform 2, isoform 3 and isoform 4. 2 PublicationsVSP_050684Add
    BLAST
    Alternative sequencei506 – 5105Missing in isoform 2, isoform 3 and isoform 5. 2 PublicationsVSP_050685
    Alternative sequencei594 – 6018Missing in isoform 2 and isoform 6. 2 PublicationsVSP_050686

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY206701 mRNA. Translation: AAO17153.1.
    BK001028 mRNA. Translation: DAA01470.1.
    BC011470 mRNA. Translation: AAH11470.1.
    BC021491 mRNA. Translation: AAH21491.1.
    BC023843 mRNA. Translation: AAH23843.1.
    BC025566 mRNA. Translation: AAH25566.1.
    BC027116 mRNA. Translation: AAH27116.1.
    BC057683 mRNA. Translation: AAH57683.1.
    AK085472 mRNA. Translation: BAC39454.2. Different initiation.
    AK162360 mRNA. Translation: BAE36872.1.
    CCDSiCCDS52307.1. [Q7M6Y3-1]
    RefSeqiNP_001239449.1. NM_001252520.1. [Q7M6Y3-5]
    NP_001239450.1. NM_001252521.1. [Q7M6Y3-6]
    NP_001239451.1. NM_001252522.1. [Q7M6Y3-4]
    NP_001239452.1. NM_001252523.1. [Q7M6Y3-3]
    NP_001239453.1. NM_001252524.1. [Q7M6Y3-2]
    NP_666306.2. NM_146194.4. [Q7M6Y3-1]
    UniGeneiMm.235175.
    Mm.393563.

    Genome annotation databases

    EnsembliENSMUST00000049537; ENSMUSP00000051092; ENSMUSG00000039361. [Q7M6Y3-1]
    GeneIDi233489.
    KEGGimmu:233489.
    UCSCiuc009igq.2. mouse. [Q7M6Y3-1]
    uc009igr.2. mouse. [Q7M6Y3-5]
    uc009igs.2. mouse. [Q7M6Y3-6]
    uc009igt.2. mouse. [Q7M6Y3-4]
    uc009igu.2. mouse. [Q7M6Y3-3]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY206701 mRNA. Translation: AAO17153.1 .
    BK001028 mRNA. Translation: DAA01470.1 .
    BC011470 mRNA. Translation: AAH11470.1 .
    BC021491 mRNA. Translation: AAH21491.1 .
    BC023843 mRNA. Translation: AAH23843.1 .
    BC025566 mRNA. Translation: AAH25566.1 .
    BC027116 mRNA. Translation: AAH27116.1 .
    BC057683 mRNA. Translation: AAH57683.1 .
    AK085472 mRNA. Translation: BAC39454.2 . Different initiation.
    AK162360 mRNA. Translation: BAE36872.1 .
    CCDSi CCDS52307.1. [Q7M6Y3-1 ]
    RefSeqi NP_001239449.1. NM_001252520.1. [Q7M6Y3-5 ]
    NP_001239450.1. NM_001252521.1. [Q7M6Y3-6 ]
    NP_001239451.1. NM_001252522.1. [Q7M6Y3-4 ]
    NP_001239452.1. NM_001252523.1. [Q7M6Y3-3 ]
    NP_001239453.1. NM_001252524.1. [Q7M6Y3-2 ]
    NP_666306.2. NM_146194.4. [Q7M6Y3-1 ]
    UniGenei Mm.235175.
    Mm.393563.

    3D structure databases

    ProteinModelPortali Q7M6Y3.
    SMRi Q7M6Y3. Positions 20-288.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 231417. 2 interactions.
    IntActi Q7M6Y3. 3 interactions.
    MINTi MINT-1850199.
    STRINGi 10090.ENSMUSP00000051092.

    PTM databases

    PhosphoSitei Q7M6Y3.

    Proteomic databases

    MaxQBi Q7M6Y3.
    PaxDbi Q7M6Y3.
    PRIDEi Q7M6Y3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000049537 ; ENSMUSP00000051092 ; ENSMUSG00000039361 . [Q7M6Y3-1 ]
    GeneIDi 233489.
    KEGGi mmu:233489.
    UCSCi uc009igq.2. mouse. [Q7M6Y3-1 ]
    uc009igr.2. mouse. [Q7M6Y3-5 ]
    uc009igs.2. mouse. [Q7M6Y3-6 ]
    uc009igt.2. mouse. [Q7M6Y3-4 ]
    uc009igu.2. mouse. [Q7M6Y3-3 ]

    Organism-specific databases

    CTDi 8301.
    MGIi MGI:2385902. Picalm.

    Phylogenomic databases

    eggNOGi NOG267212.
    GeneTreei ENSGT00390000008805.
    HOVERGENi HBG049391.
    InParanoidi Q7M6Y3.
    OMAi WNAATMA.
    OrthoDBi EOG76QFM8.
    PhylomeDBi Q7M6Y3.
    TreeFami TF314861.

    Miscellaneous databases

    ChiTaRSi PICALM. mouse.
    NextBioi 381725.
    PROi Q7M6Y3.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q7M6Y3.
    Genevestigatori Q7M6Y3.

    Family and domain databases

    Gene3Di 1.20.58.150. 1 hit.
    1.25.40.90. 1 hit.
    InterProi IPR011417. ANTH_dom.
    IPR014712. Clathrin_Pinositid-bd_GAT-like.
    IPR008942. ENTH_VHS.
    IPR013809. Epsin-like_N.
    [Graphical view ]
    Pfami PF07651. ANTH. 1 hit.
    [Graphical view ]
    SMARTi SM00273. ENTH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48464. SSF48464. 1 hit.
    PROSITEi PS50942. ENTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice."
      Klebig M.L., Wall M.D., Potter M.D., Rowe E.L., Carpenter D.A., Rinchik E.M.
      Proc. Natl. Acad. Sci. U.S.A. 100:8360-8365(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY.
      Strain: BALB/cRlImported.
      Tissue: LiverImported.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3; 4; 5 AND 6).
      Strain: Czech II and FVB/NImported.
      Tissue: Mammary tumor and Retina.
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 143-660 (ISOFORM 2).
      Strain: C57BL/6J.
      Tissue: Epididymis and Kidney.
    4. "Mutations in the murine fitness 1 gene result in defective hematopoiesis."
      Potter M.D., Shinpock S.G., Popp R.A., Godfrey V., Carpenter D.A., Bernstein A., Johnson D.K., Rinchik E.M.
      Blood 90:1850-1857(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.

    Entry informationi

    Entry nameiPICAL_MOUSE
    AccessioniPrimary (citable) accession number: Q7M6Y3
    Secondary accession number(s): Q3TS04
    , Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2004
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3