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Q7M3Y8 (TPM_TURCO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tropomyosin
Alternative name(s):
Major allergen Tur c 1
Allergen=Tur c 1
OrganismTurbo cornutus (Horned turban) (Battilus cornutus)
Taxonomic identifier63673 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaGastropodaVetigastropodaTrochoideaTurbinidaeTurboBatillus

Protein attributes

Sequence length146 AA.
Sequence statusFragments.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Subunit structure

Homodimer By similarity.

Domain

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the tropomyosin family.

Ontologies

Keywords
   DiseaseAllergen
   DomainCoiled coil
Repeat
   Technical termDirect protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 146›146Tropomyosin
PRO_0000205672

Regions

Coiled coil‹1 – 146›146 By similarity

Experimental info

Non-adjacent residues20 – 212
Non-adjacent residues47 – 482
Non-adjacent residues55 – 562
Non-adjacent residues77 – 782
Non-adjacent residues106 – 1072
Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q7M3Y8 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: CAA859DA08A320F6

FASTA14616,839
        10         20         30         40         50         60 
AANLENDFDN VNEQLQDALS KITLLEEDLE RNEERLQTAT ERLEEASKYI AEDAERKLAI 

        70         80         90        100        110        120 
TEVDLERAEA RLEAAEAKSL EISEQEASQR EDSYEETIRD LTQRLKTVSK LQKEVDRLED 

       130        140 
ELLAEKEKYK AISDELDQTF AELAGY 

« Hide

References

[1]"Purification and IgE-binding epitopes of a major allergen in the gastropod Turbo cornutus."
Ishikawa M., Ishida M., Shimakura K., Nagashima Y., Shiomi K.
Biosci. Biotechnol. Biochem. 62:1337-1343(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Muscle.

Cross-references

Sequence databases

PIRJE0229.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome656. Tur c 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR000533. Tropomyosin.
[Graphical view]
PfamPF00261. Tropomyosin. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPM_TURCO
AccessionPrimary (citable) accession number: Q7M3Y8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries