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Q7M3Y8

- TPM_TURCO

UniProt

Q7M3Y8 - TPM_TURCO

Protein

Tropomyosin

Gene
N/A
Organism
Turbo cornutus (Horned turban) (Battilus cornutus)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tropomyosin
    Alternative name(s):
    Major allergen Tur c 1
    Allergen: Tur c 1
    OrganismiTurbo cornutus (Horned turban) (Battilus cornutus)
    Taxonomic identifieri63673 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaVetigastropodaTrochoideaTurbinidaeTurboBatillus

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei656. Tur c 1.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 146›146TropomyosinPRO_0000205672Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili‹1 – 146›146By similarityAdd
    BLAST

    Domaini

    The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

    Sequence similaritiesi

    Belongs to the tropomyosin family.Curated

    Keywords - Domaini

    Coiled coil, Repeat

    Family and domain databases

    InterProiIPR000533. Tropomyosin.
    [Graphical view]
    PfamiPF00261. Tropomyosin. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragments.

    Q7M3Y8-1 [UniParc]FASTAAdd to Basket

    « Hide

    AANLENDFDN VNEQLQDALS KITLLEEDLE RNEERLQTAT ERLEEASKYI    50
    AEDAERKLAI TEVDLERAEA RLEAAEAKSL EISEQEASQR EDSYEETIRD 100
    LTQRLKTVSK LQKEVDRLED ELLAEKEKYK AISDELDQTF AELAGY 146
    Length:146
    Mass (Da):16,839
    Last modified:December 15, 2003 - v1
    Checksum:iCAA859DA08A320F6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-adjacent residuesi20 – 212Curated
    Non-adjacent residuesi47 – 482Curated
    Non-adjacent residuesi55 – 562Curated
    Non-adjacent residuesi77 – 782Curated
    Non-adjacent residuesi106 – 1072Curated

    Sequence databases

    PIRiJE0229.

    Cross-referencesi

    Sequence databases

    PIRi JE0229.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 656. Tur c 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR000533. Tropomyosin.
    [Graphical view ]
    Pfami PF00261. Tropomyosin. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Purification and IgE-binding epitopes of a major allergen in the gastropod Turbo cornutus."
      Ishikawa M., Ishida M., Shimakura K., Nagashima Y., Shiomi K.
      Biosci. Biotechnol. Biochem. 62:1337-1343(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Muscle.

    Entry informationi

    Entry nameiTPM_TURCO
    AccessioniPrimary (citable) accession number: Q7M3Y8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 10, 2004
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3