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Protein

Vespakinin-M

Gene
N/A
Organism
Vespa mandarinia (Asian giant hornet)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Bradykinins are a potent but short-lived agent of arteriolar dilation and increased capillary permeability (By similarity). May target bradykinin receptors (BDKRB). May cause hypotension.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionBradykinin receptor impairing toxin, G-protein coupled receptor impairing toxin, Hypotensive agent, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
Vespakinin-M
OrganismiVespa mandarinia (Asian giant hornet)
Taxonomic identifieri7446 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataVespoideaVespidaeVespinaeVespa

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000435171 – 12Vespakinin-MAdd BLAST12

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei44-hydroxyproline1 Publication1

Keywords - PTMi

Hydroxylation

Expressioni

Tissue specificityi

Expressed by the venom gland.

Family & Domainsi

Sequence similaritiesi

Belongs to the bradykinin-related peptide family.Curated

Sequencei

Sequence statusi: Complete.

Length:12
Mass (Da):1,346
Last modified:December 15, 2003 - v1
Checksum:i34F513C44C75B9C8
GO

Sequence databases

PIRiA61360.

Similar proteinsi

Entry informationi

Entry nameiBRK_VESMA
AccessioniPrimary (citable) accession number: Q7M3T3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: November 22, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families