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Q7M1T4

- Q7M1T4_ARTIN

UniProt

Q7M1T4 - Q7M1T4_ARTIN

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Protein
Submitted name: Mannose-specific lectin KM+
Gene
N/A
Organism
Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151Mannose; via amide nitrogen
Metal bindingi114 – 1141CadmiumImported
Metal bindingi116 – 1161CadmiumImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

CadmiumImported, Metal-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
Mannose-specific lectin KM+Imported
OrganismiArtocarpus integer (Jack fruit) (Artocarpus integrifolia)Imported
Taxonomic identifieri3490 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesMoraceaeArtocarpus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylalanineImported

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J4SX-ray2.50A/B/C/D1-149[»]
1J4TX-ray2.40A/B/C/D/E/F/G/H1-149[»]
1J4UX-ray2.90A/B/C/D1-149[»]
1VBOX-ray2.35A/B/C/D/E/F/G/H1-147[»]
1VBPX-ray3.50A/B1-147[»]
4AKDX-ray2.10A/B/C/D1-149[»]
ProteinModelPortaliQ7M1T4.
SMRiQ7M1T4. Positions 1-149.

Miscellaneous databases

EvolutionaryTraceiQ7M1T4.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni90 – 934Mannose binding
Regioni137 – 1415Mannose binding

Family and domain databases

Gene3Di2.100.10.30. 1 hit.
InterProiIPR001229. Mannose-bd_lectin.
[Graphical view]
PfamiPF01419. Jacalin. 1 hit.
[Graphical view]
SMARTiSM00915. Jacalin. 1 hit.
[Graphical view]
SUPFAMiSSF51101. SSF51101. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7M1T4-1 [UniParc]FASTAAdd to Basket

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ASQTITVGPW GGPGGNGWDD GSYTGIRQIE LSYKEAIGSF SVIYDLNGEP    50
FSGPKHTSKL PYKNVKIELR FPDEFLESVS GYTAPFSALA TPTPVVRSLT 100
FKTNKGRTFG PYGDEEGTYF NLPIENGLIV GFKGRTGDLL DAIGVHMAL 149
Length:149
Mass (Da):16,082
Last modified:December 15, 2003 - v1
Checksum:iA958A6EEE50F4E9D
GO

Sequence databases

PIRiA58801.

Cross-referencesi

Sequence databases

PIRi A58801.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1J4S X-ray 2.50 A/B/C/D 1-149 [» ]
1J4T X-ray 2.40 A/B/C/D/E/F/G/H 1-149 [» ]
1J4U X-ray 2.90 A/B/C/D 1-149 [» ]
1VBO X-ray 2.35 A/B/C/D/E/F/G/H 1-147 [» ]
1VBP X-ray 3.50 A/B 1-147 [» ]
4AKD X-ray 2.10 A/B/C/D 1-149 [» ]
ProteinModelPortali Q7M1T4.
SMRi Q7M1T4. Positions 1-149.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q7M1T4.

Family and domain databases

Gene3Di 2.100.10.30. 1 hit.
InterProi IPR001229. Mannose-bd_lectin.
[Graphical view ]
Pfami PF01419. Jacalin. 1 hit.
[Graphical view ]
SMARTi SM00915. Jacalin. 1 hit.
[Graphical view ]
SUPFAMi SSF51101. SSF51101. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: PROTEIN SEQUENCE.
  2. "Crystal structures of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-alpha-D-mannose: implications to the generation of carbohydrate specificity."
    Pratap J.V., Jeyaprakash A.A., Rani P.G., Sekar K., Surolia A., Vijayan M.
    J. Mol. Biol. 317:237-247(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS), ACETYLATION AT ALA-1.
  3. "Structural basis for the carbohydrate specificities of artocarpin: variation in the length of a loop as a strategy for generating ligand specificity."
    Jeyaprakash A.A., Srivastav A., Surolia A., Vijayan M.
    J. Mol. Biol. 338:757-770(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 1-147 IN COMPLEX WITH MANNOSE.
  4. "Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences from jackfruit lectins."
    Gabrielsen M., Abdul-Rahman P.S., Othman S., Hashim O.H., Cogdell R.J.
    Acta Crystallogr F Struct Biol Commun 70:709-716(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH CADMIUM.

Entry informationi

Entry nameiQ7M1T4_ARTIN
AccessioniPrimary (citable) accession number: Q7M1T4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: September 3, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Direct protein sequencing

External Data

Dasty 3

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