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Protein
Submitted name:

Mannose-specific lectin KM+

Gene
N/A
Organism
Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151Mannose; via amide nitrogenCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Mannose-specific lectin KM+Imported
OrganismiArtocarpus integer (Jack fruit) (Artocarpus integrifolia)Imported
Taxonomic identifieri3490 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesMoraceaeArtocarpus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylalanineCombined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J4SX-ray2.50A/B/C/D1-149[»]
1J4TX-ray2.40A/B/C/D/E/F/G/H1-149[»]
1J4UX-ray2.90A/B/C/D1-149[»]
1VBOX-ray2.35A/B/C/D/E/F/G/H1-147[»]
1VBPX-ray3.50A/B1-147[»]
4AKDX-ray2.10A/B/C/D1-149[»]
ProteinModelPortaliQ7M1T4.
SMRiQ7M1T4. Positions 1-149.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7M1T4.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni90 – 934Mannose bindingCombined sources
Regioni137 – 1415Mannose bindingCombined sources

Family and domain databases

Gene3Di2.100.10.30. 1 hit.
InterProiIPR001229. Jacalin-like_lectin_dom.
[Graphical view]
PfamiPF01419. Jacalin. 1 hit.
[Graphical view]
SMARTiSM00915. Jacalin. 1 hit.
[Graphical view]
SUPFAMiSSF51101. SSF51101. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7M1T4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ASQTITVGPW GGPGGNGWDD GSYTGIRQIE LSYKEAIGSF SVIYDLNGEP
60 70 80 90 100
FSGPKHTSKL PYKNVKIELR FPDEFLESVS GYTAPFSALA TPTPVVRSLT
110 120 130 140
FKTNKGRTFG PYGDEEGTYF NLPIENGLIV GFKGRTGDLL DAIGVHMAL
Length:149
Mass (Da):16,082
Last modified:December 15, 2003 - v1
Checksum:iA958A6EEE50F4E9D
GO

Sequence databases

PIRiA58801.

Cross-referencesi

Sequence databases

PIRiA58801.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1J4SX-ray2.50A/B/C/D1-149[»]
1J4TX-ray2.40A/B/C/D/E/F/G/H1-149[»]
1J4UX-ray2.90A/B/C/D1-149[»]
1VBOX-ray2.35A/B/C/D/E/F/G/H1-147[»]
1VBPX-ray3.50A/B1-147[»]
4AKDX-ray2.10A/B/C/D1-149[»]
ProteinModelPortaliQ7M1T4.
SMRiQ7M1T4. Positions 1-149.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ7M1T4.

Family and domain databases

Gene3Di2.100.10.30. 1 hit.
InterProiIPR001229. Jacalin-like_lectin_dom.
[Graphical view]
PfamiPF01419. Jacalin. 1 hit.
[Graphical view]
SMARTiSM00915. Jacalin. 1 hit.
[Graphical view]
SUPFAMiSSF51101. SSF51101. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: PROTEIN SEQUENCE.
  2. "Crystal structures of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-alpha-D-mannose: implications to the generation of carbohydrate specificity."
    Pratap J.V., Jeyaprakash A.A., Rani P.G., Sekar K., Surolia A., Vijayan M.
    J. Mol. Biol. 317:237-247(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS), ACETYLATION AT ALA-1.
  3. "Structural basis for the carbohydrate specificities of artocarpin: variation in the length of a loop as a strategy for generating ligand specificity."
    Jeyaprakash A.A., Srivastav A., Surolia A., Vijayan M.
    J. Mol. Biol. 338:757-770(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 1-147 IN COMPLEX WITH MANNOSE.
  4. "Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences from jackfruit lectins."
    Gabrielsen M., Abdul-Rahman P.S., Othman S., Hashim O.H., Cogdell R.J.
    Acta Crystallogr F Struct Biol Commun 70:709-716(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).

Entry informationi

Entry nameiQ7M1T4_ARTIN
AccessioniPrimary (citable) accession number: Q7M1T4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: January 7, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Direct protein sequencing

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.