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Q7M1T4

- Q7M1T4_ARTIN

UniProt

Q7M1T4 - Q7M1T4_ARTIN

Protein
Submitted name:

Mannose-specific lectin KM+

Gene
N/A
Organism
Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151Mannose; via amide nitrogenImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mannose-specific lectin KM+Imported
    OrganismiArtocarpus integer (Jack fruit) (Artocarpus integrifolia)Imported
    Taxonomic identifieri3490 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesMoraceaeArtocarpus

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylalanineImported

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1J4SX-ray2.50A/B/C/D1-149[»]
    1J4TX-ray2.40A/B/C/D/E/F/G/H1-149[»]
    1J4UX-ray2.90A/B/C/D1-149[»]
    1VBOX-ray2.35A/B/C/D/E/F/G/H1-147[»]
    1VBPX-ray3.50A/B1-147[»]
    4AKDX-ray2.10A/B/C/D1-149[»]
    ProteinModelPortaliQ7M1T4.
    SMRiQ7M1T4. Positions 1-149.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ7M1T4.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni90 – 934Mannose bindingImported
    Regioni137 – 1415Mannose bindingImported

    Family and domain databases

    Gene3Di2.100.10.30. 1 hit.
    InterProiIPR001229. Mannose-bd_lectin.
    [Graphical view]
    PfamiPF01419. Jacalin. 1 hit.
    [Graphical view]
    SMARTiSM00915. Jacalin. 1 hit.
    [Graphical view]
    SUPFAMiSSF51101. SSF51101. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7M1T4-1 [UniParc]FASTAAdd to Basket

    « Hide

    ASQTITVGPW GGPGGNGWDD GSYTGIRQIE LSYKEAIGSF SVIYDLNGEP    50
    FSGPKHTSKL PYKNVKIELR FPDEFLESVS GYTAPFSALA TPTPVVRSLT 100
    FKTNKGRTFG PYGDEEGTYF NLPIENGLIV GFKGRTGDLL DAIGVHMAL 149
    Length:149
    Mass (Da):16,082
    Last modified:December 15, 2003 - v1
    Checksum:iA958A6EEE50F4E9D
    GO

    Sequence databases

    PIRiA58801.

    Cross-referencesi

    Sequence databases

    PIRi A58801.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1J4S X-ray 2.50 A/B/C/D 1-149 [» ]
    1J4T X-ray 2.40 A/B/C/D/E/F/G/H 1-149 [» ]
    1J4U X-ray 2.90 A/B/C/D 1-149 [» ]
    1VBO X-ray 2.35 A/B/C/D/E/F/G/H 1-147 [» ]
    1VBP X-ray 3.50 A/B 1-147 [» ]
    4AKD X-ray 2.10 A/B/C/D 1-149 [» ]
    ProteinModelPortali Q7M1T4.
    SMRi Q7M1T4. Positions 1-149.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q7M1T4.

    Family and domain databases

    Gene3Di 2.100.10.30. 1 hit.
    InterProi IPR001229. Mannose-bd_lectin.
    [Graphical view ]
    Pfami PF01419. Jacalin. 1 hit.
    [Graphical view ]
    SMARTi SM00915. Jacalin. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51101. SSF51101. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: PROTEIN SEQUENCE.
    2. "Crystal structures of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-alpha-D-mannose: implications to the generation of carbohydrate specificity."
      Pratap J.V., Jeyaprakash A.A., Rani P.G., Sekar K., Surolia A., Vijayan M.
      J. Mol. Biol. 317:237-247(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS), ACETYLATION AT ALA-1.
    3. "Structural basis for the carbohydrate specificities of artocarpin: variation in the length of a loop as a strategy for generating ligand specificity."
      Jeyaprakash A.A., Srivastav A., Surolia A., Vijayan M.
      J. Mol. Biol. 338:757-770(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 1-147 IN COMPLEX WITH MANNOSE.
    4. "Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences from jackfruit lectins."
      Gabrielsen M., Abdul-Rahman P.S., Othman S., Hashim O.H., Cogdell R.J.
      Acta Crystallogr F Struct Biol Commun 70:709-716(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).

    Entry informationi

    Entry nameiQ7M1T4_ARTIN
    AccessioniPrimary (citable) accession number: Q7M1T4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Direct protein sequencing

    External Data

    Dasty 3