Reviewed, UniProtKB/Swiss-Prot Q7M1G9 (ALL2_ARTVU)

Names and origin

Protein names	Recommended name:     Allergen Art v 2 Alternative name(s):     Allergen Art v II     Allergen Ag7     Allergen=Art v 2
Organism	Artemisia vulgaris (Mugwort)
Taxonomic identifier	4220 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Anthemideae › Artemisia

Protein attributes

Sequence length	71 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Post-translational modification	Glycosylated. High-manose oligosaccharides (Man5-9GlcNAc2). Ref.1 Ref.2
Allergenic properties	Causes an allergic reaction in human.
Miscellaneous	Consists of 6 isoforms with different pI. The IgE-binding epitopes are not significantly affected by the deglycosylation of the allergen.

Ontologies

Keywords
Disease	Allergen
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 71	71	Allergen Art v 2		PRO_0000064558
Experimental info
	Sequence uncertainty	20	1
	Sequence uncertainty	23	1
	Sequence uncertainty	25	1	L or K
	Sequence uncertainty	61	1
	Sequence uncertainty	69	1	L or K
	Non-adjacent residues	30 – 31	2
	Non-adjacent residues	39 – 40	2
	Non-adjacent residues	60 – 61	2

Sequences

	Sequence		Length	Mass (Da)
	Q7M1G9-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: B89BE3F14A6ADB02	FASTA	71	7,875
	10 20 30 40 50 60 XETYGEPGNT PDDYVHAHNN IRRVLGMXPK XQGAIDGSSX VQLXLDEXLD YDYNXNKXIK 70 PPGNVVGQLP Y

References

[1]	"Structural analysis of the glycoprotein allergen Art v II from the pollen of mugwort (Artemisia vulgaris L.)." Nilsen B.M., Sletten K., Paulsen B.S., O'Neill M., van Halbeek H. J. Biol. Chem. 266:2660-2668(1991) [PubMed: 1703533] [Abstract] Cited for: PROTEIN SEQUENCE, GLYCOSYLATION. Tissue: Pollen.
[2]	"Isolation and characterization of a glycoprotein allergen, Art v II, from pollen of mugwort (Artemisia vulgaris L.)." Nilsen B.M., Paulsen B.S. Mol. Immunol. 27:1047-1056(1990) [PubMed: 2233755] [Abstract] Cited for: IDENTIFICATION, GLYCOSYLATION.

Cross-references

Sequence databases
PIR	A38624.
3D structure databases
ModBase	Search...
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

ALL2_ARTVU

Accession

Primary (citable) accession number: Q7M1G9

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	December 15, 2003
Last modified:	September 23, 2008
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)