Q7M0H9 (Q7M0H9_CRIGR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Ca2+/calmodulin-dependent protein kinase ERK1 PIR A60041 EC=2.7.1.123 PIR A60041
Organism	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) PIR A60041
Taxonomic identifier	10029 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Cricetidae › Cricetinae › Cricetulus

Protein attributes

Sequence length	369 AA.
Sequence status	Fragment.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS003527
Sequence similarities	Contains 1 protein kinase domain. SAAS SAAS003527

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 SAAS SAAS003527 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS003527 Transferase
Gene Ontology (GO)
Biological_process	MAPK cascade Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW MAP kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	PIR A60041
	Non-terminal residue	369	1	PIR A60041

Sequences

	Sequence		Length	Mass (Da)
	Q7M0H9 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 0BB8FCAAC690B4FF	FASTA	369	42,126
	10 20 30 40 50 60 GGEPRGAAGV GPGVPGEVEV VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI 70 80 90 100 110 120 KKISPFEHQT YCQRTLREIQ ILLRFRHENV IGIRDILRAP TLEAMRDVYI VQDLMETDLY 130 140 150 160 170 180 KLLKSQQLSN DHICYFLYQI LRGLKYIHSA NVLHRDLKPS NLLINTTCDL KICDFGLARI 190 200 210 220 230 240 ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS NRPIFPGKHY 250 260 270 280 290 300 LDQLNHILGI LGSPSQEDLN CIINMKARNY LQSLPSKTKV AWAKLFPKSD SKALDLLDRM 310 320 330 340 350 360 LTFNPNKRIT VEDALAHPYL EQYYDPTDEP VAEEPFTFDM ELDDLPKERL KELIFQETAR FQPGAPEAP

References

[1]	"Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk." Meloche S., Pages G., Pouyssegur J. Mol. Biol. Cell 3:63-71(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
PIR	A60041.
3D structure databases
HSSP	HSSP built from PDB template 1OZ1 based on UniProtKB Q16539.
ProteinModelPortal	Q7M0H9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG014652.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR003527. MAP_kinase_CS. IPR008349. MAPK_ERK1/2. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PRINTS	PR01770. ERK1ERK2MAPK.
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS01351. MAPK. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7M0H9_CRIGR

Accession

Primary (citable) accession number: Q7M0H9

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)