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Protein

39S ribosomal protein L14, mitochondrial

Gene

Mrpl14

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May form part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-5389840. Mitochondrial translation elongation.
R-RNO-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L14, mitochondrial
Short name:
L14mt
Short name:
MRP-L14
Alternative name(s):
39S ribosomal protein L32, mitochondrial
Short name:
L32mt
Short name:
MRP-L32
Gene namesi
Name:Mrpl14
Synonyms:Rpml32
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1306240. Mrpl14.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3030Mitochondrion1 PublicationAdd
BLAST
Chaini31 – 14511539S ribosomal protein L14, mitochondrialPRO_0000261136Add
BLAST

Proteomic databases

PaxDbiQ7M0E7.
PRIDEiQ7M0E7.

PTM databases

iPTMnetiQ7M0E7.
PhosphoSiteiQ7M0E7.

Expressioni

Gene expression databases

BgeeiENSRNOG00000019734.
GenevisibleiQ7M0E7. RN.

Interactioni

Subunit structurei

Part of the mitochondrial ribosome large subunit (39S); associates with MALSU1.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026716.

Structurei

3D structure databases

ProteinModelPortaliQ7M0E7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L14P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3441. Eukaryota.
ENOG4111JDP. LUCA.
GeneTreeiENSGT00390000001121.
HOGENOMiHOG000183701.
HOVERGENiHBG088508.
InParanoidiQ7M0E7.
KOiK02874.
OMAiHRMPGPR.
OrthoDBiEOG091G1144.
PhylomeDBiQ7M0E7.
TreeFamiTF324586.

Family and domain databases

Gene3Di2.40.150.20. 1 hit.
HAMAPiMF_01367. Ribosomal_L14. 1 hit.
InterProiIPR000218. Ribosomal_L14P.
[Graphical view]
PfamiPF00238. Ribosomal_L14. 1 hit.
[Graphical view]
SMARTiSM01374. Ribosomal_L14. 1 hit.
[Graphical view]
SUPFAMiSSF50193. SSF50193. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7M0E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVLTGLFGF FAYVRGAVSQ RCFSTSGSLS AIQKMTRVRV VDNSALGNTP
60 70 80 90 100
YHRPPRCIHV YNKSGVGKVG DQILLAIRGQ KKKALIVGHR MPGSRMTPKF
110 120 130 140
DSNNVVLIED NGNPVGTRIK IPIPTSLRRR EGEYSKVLAI AQNFV
Length:145
Mass (Da):15,913
Last modified:November 28, 2006 - v2
Checksum:i3AF4E7FF76436D23
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti57 – 571C → E AA sequence (PubMed:9857009).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03068353 Genomic DNA. No translation available.
PIRiS78418.
RefSeqiNP_001100360.1. NM_001106890.2.
NP_001258060.1. NM_001271131.1.
XP_006244574.1. XM_006244512.2.
XP_008765072.1. XM_008766850.1.
UniGeneiRn.35669.

Genome annotation databases

EnsembliENSRNOT00000026716; ENSRNOP00000026716; ENSRNOG00000019734.
ENSRNOT00000087528; ENSRNOP00000072412; ENSRNOG00000019734.
GeneIDi301250.
KEGGirno:301250.
UCSCiRGD:1306240. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03068353 Genomic DNA. No translation available.
PIRiS78418.
RefSeqiNP_001100360.1. NM_001106890.2.
NP_001258060.1. NM_001271131.1.
XP_006244574.1. XM_006244512.2.
XP_008765072.1. XM_008766850.1.
UniGeneiRn.35669.

3D structure databases

ProteinModelPortaliQ7M0E7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026716.

PTM databases

iPTMnetiQ7M0E7.
PhosphoSiteiQ7M0E7.

Proteomic databases

PaxDbiQ7M0E7.
PRIDEiQ7M0E7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000026716; ENSRNOP00000026716; ENSRNOG00000019734.
ENSRNOT00000087528; ENSRNOP00000072412; ENSRNOG00000019734.
GeneIDi301250.
KEGGirno:301250.
UCSCiRGD:1306240. rat.

Organism-specific databases

CTDi64928.
RGDi1306240. Mrpl14.

Phylogenomic databases

eggNOGiKOG3441. Eukaryota.
ENOG4111JDP. LUCA.
GeneTreeiENSGT00390000001121.
HOGENOMiHOG000183701.
HOVERGENiHBG088508.
InParanoidiQ7M0E7.
KOiK02874.
OMAiHRMPGPR.
OrthoDBiEOG091G1144.
PhylomeDBiQ7M0E7.
TreeFamiTF324586.

Enzyme and pathway databases

ReactomeiR-RNO-5389840. Mitochondrial translation elongation.
R-RNO-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiQ7M0E7.

Gene expression databases

BgeeiENSRNOG00000019734.
GenevisibleiQ7M0E7. RN.

Family and domain databases

Gene3Di2.40.150.20. 1 hit.
HAMAPiMF_01367. Ribosomal_L14. 1 hit.
InterProiIPR000218. Ribosomal_L14P.
[Graphical view]
PfamiPF00238. Ribosomal_L14. 1 hit.
[Graphical view]
SMARTiSM01374. Ribosomal_L14. 1 hit.
[Graphical view]
SUPFAMiSSF50193. SSF50193. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRM14_RAT
AccessioniPrimary (citable) accession number: Q7M0E7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: September 7, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.