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Protein

Phyllokinin

Gene
N/A
Organism
Phyllomedusa rohdei (Rohde's leaf frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB).By similarity

GO - Biological processi

Keywordsi

Molecular functionAmphibian defense peptide, G-protein coupled receptor impairing toxin, Toxin, Vasoactive, Vasodilator

Names & Taxonomyi

Protein namesi
Recommended name:
Phyllokinin
Alternative name(s):
Bradykinyl-isoleucyl-tyrosine O-sulfate
OrganismiPhyllomedusa rohdei (Rohde's leaf frog)
Taxonomic identifieri8394 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaHyloideaHylidaePhyllomedusinaePhyllomedusa

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000435221 – 11PhyllokininAdd BLAST11

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11Sulfotyrosine1 Publication1

Keywords - PTMi

Sulfation

Expressioni

Tissue specificityi

Expressed by the skin glands.

Family & Domainsi

Sequence similaritiesi

Belongs to the bradykinin-related peptide family.Curated

Phylogenomic databases

HOVERGENiHBG048769.

Sequencei

Sequence statusi: Complete.

Length:11
Mass (Da):1,337
Last modified:December 15, 2003 - v1
Checksum:i25051393D775B9C8
GO

Sequence databases

PIRiA61365.

Similar proteinsi

Entry informationi

Entry nameiBRKP_PHYRO
AccessioniPrimary (citable) accession number: Q7LZ52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: December 15, 2003
Last modified: January 7, 2015
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families