Unreviewed, UniProtKB/TrEMBL Q7LBY6 (Q7LBY6_HUMAN)

Names and origin

Protein names

Submitted name:
IKBKG protein EMBL AAH46922.1

Submitted name:
NFkappaB essential modulator EMBL AAL27012.1

Gene names

Name:	NEMO EMBL AAL27012.1
Synonyms:	IKBKG EMBL AAH46922.1

Organism

Homo sapiens (Human) EMBL AAL27012.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

Sequences

	Sequence		Length	Mass (Da)
	Q7LBY6-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 322D1037881447FF	FASTA	419	48,198
	10 20 30 40 50 60 MNRHLWKSQL CEMVQPSGGP AADQDVLGEE SPLGKPAMLH LPSEQGAPET LQRCLEENQE 70 80 90 100 110 120 LRDAIRQSNQ ILRERCEELL HFQASQREEK EFLMCKFQEA RKLVERLGLE KLDLKRQKEQ 130 140 150 160 170 180 ALREVEHLKR CQQQMAEDKA SVKAQVTSLL GELQESQSRL EAATKECQAL EGRARAASEQ 190 200 210 220 230 240 ARQLESEREA LQQQHSVQVD QLRMQGQSVE AALRMERQAA SEEKRKLAQL QVAYHQLFQE 250 260 270 280 290 300 YDNHIKSSVV GSERKRGMQL EDLKQQLQQA EEALVAKQEV IDKLKEEAEQ HKIVMETVPV 310 320 330 340 350 360 LKAQADIYKA DFQAERQARE KLAEKKELLQ EQLEQLQREY SKLKASCQES ARIEDMRKRH 370 380 390 400 410 VEVSQAPLPP APAYLSSPLA LPSQRRSPPE EPPDFCCPKC QYQAPDMDTL QIHVMECIE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human-mouse comparative sequence analysis of the NEMO gene reveals an alternative promoter within the neighboring G6PD gene." Galgoczy P., Rosenthal A., Platzer M. Gene 271:93-98(2001) [PubMed: 11410370] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Multiple pathogenic and benign genomic rearrangements occur at a 35 kb duplication involving the NEMO and LAGE2 genes." Aradhya S., Bardaro T., Galgoczy P., Yamagata T., Esposito T., Patlan H., Ciccodicola A., Kenwrick S., Platzer M., D'Urso M., Nelson D.L. Hum. Mol. Genet. 10:2557-2567(2001) [PubMed: 11709543] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Galgoczy P., Platzer M. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Skin EMBL AAH46922.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC046922 mRNA. Translation: AAH46922.1. AF277315 Genomic DNA. Translation: AAL27012.1.
IPI	IPI00002411.
RefSeq	NP_001093327.1. NP_003630.1.
UniGene	Hs.43505
3D structure databases
SMR	Q7LBY6. Positions 49-109, 193-251, 394-419.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7LBY6.
Proteomic databases
PRIDE	Q7LBY6.
Genome annotation databases
Ensembl	ENST00000369601; ENSP00000358614; ENSG00000073009; Homo sapiens. [Genome view] ENST00000369606; ENSP00000358619; ENSG00000073009; Homo sapiens. [Genome view] ENST00000369607; ENSP00000358620; ENSG00000073009; Homo sapiens. [Genome view] ENST00000369609; ENSP00000358622; ENSG00000073009; Homo sapiens. [Genome view]
GeneID	8517.
Organism-specific databases
CTD	8517.
HGNC	HGNC:5961. IKBKG.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG04970.
HOVERGEN	HBG000417.
PhylomeDB	Q7LBY6.
Gene expression databases
ArrayExpress	Q7LBY6.
Bgee	Q7LBY6.
Family and domain databases
InterPro	IPR021063. NEMO. [Graphical view]
Pfam	PF11577. NEMO. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	31882.

Entry information

Entry name

Q7LBY6_HUMAN

Accession

Primary (citable) accession number: Q7LBY6

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	March 2, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.