Unreviewed,
UniProtKB/TrEMBL Q7LA65 (Q7LA65_HUMAN)
Last modified
February 9, 2010.
Version 49.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information
Names and origin
| Protein names | Submitted name: Nuclear factor of activated T-cells EMBL AAK91166.1 Submitted name: Tonicity-responsive enhancer binding protein EMBL CAC42764.1 | ||||
| Gene names |
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| Organism | Homo sapiens (Human) EMBL CAC42764.1 | ||||
| Taxonomic identifier | 9606 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 1455 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Nucleus RuleBase RU003998V0 |
| Gene Ontology (GO) | |
| Biological process | cytokine production Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoterInferred from electronic annotation. Source: Compara |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: Compara nucleusInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | transcription factor activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
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References
| [1] | "Complete sequence, chromosomal fine mapping and genomic structure of the tonicity-response enhancer binding protein (TonEBP) in brain." Dalski A., Engel H., Mattei M.G., Ptacek L., Grzeschik K.H., Schwinger E., Zuehlke C. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. |
| [2] | "Genomic organization of the human NFAT5 gene: exon-intron structure of the 14-kb transcript and CpG-island analysis of the promoter region." Dalski A., Schwinger E., Zuhlke C. Cytogenet. Cell Genet. 93:239-241(2001) [PubMed: 11528118] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF346509 mRNA. Translation: AAK91166.1. AJ243298 mRNA. Translation: CAC42764.1. |
| IPI | IPI00218772. |
| RefSeq | NP_001106649.1. NP_006590.1. NP_619727.2. NP_619728.2. NP_775321.1. |
| UniGene | Hs.371987 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1A66 based on UniProtKB O95644. |
| SMR | Q7LA65. Positions 188-468. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q7LA65. |
Genome annotation databases | |
| Ensembl | ENST00000349945; ENSP00000338806; ENSG00000102908; Homo sapiens. [Genome view] ENST00000354436; ENSP00000346420; ENSG00000102908; Homo sapiens. [Genome view] ENST00000393742; ENSP00000377343; ENSG00000102908; Homo sapiens. [Genome view] ENST00000432919; ENSP00000396538; ENSG00000102908; Homo sapiens. [Genome view] ENST00000453403; ENSP00000387503; ENSG00000102908; Homo sapiens. [Genome view] |
| GeneID | 10725. |
| KEGG | hsa:10725. |
Organism-specific databases | |
| CTD | 10725. |
| HGNC | HGNC:7774. NFAT5. |
| GenAtlas | Search... |
Phylogenomic databases | |
| HOVERGEN | Q7LA65. |
Gene expression databases | |
| ArrayExpress | Q7LA65. |
| Bgee | Q7LA65. |
Family and domain databases | |
| InterPro | IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002909. IPT_TIG_rcpt. IPR008366. NFAT. IPR015646. NFAT5. IPR018286. NFAT_sbgrp. IPR008967. p53-like_TF_DNA-bd. IPR011539. RHD. [Graphical view] |
| Gene3D | G3DSA:2.60.40.10. Ig-like_fold. 1 hit. G3DSA:2.60.40.340. RHD. 1 hit. |
| PANTHER | PTHR12533. NFAT. 1 hit. PTHR12533:SF1. NFAT5. 1 hit. |
| Pfam | PF00554. RHD. 1 hit. [Graphical view] |
| PRINTS | PR01789. NUCFACTORATC. |
| SMART | SM00429. IPT. 1 hit. [Graphical view] |
| PROSITE | PS50254. REL_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 40713. |
Entry information
| Entry name | Q7LA65_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q7LA65 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
