Q7L8W6 (ATBD4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP-binding domain-containing protein 4

Gene names

Name:

ATPBD4

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	ATP-binding domain-containing protein 4		PRO_0000282397
Natural variations
	Natural variant	41	1	G → E. Corresponds to variant rs34907758 [ dbSNP | Ensembl ].		VAR_031403
	Natural variant	236	1	P → R. Corresponds to variant rs10519996 [ dbSNP | Ensembl ].		VAR_031404

Sequences

	Sequence		Length	Mass (Da)
	Q7L8W6 [UniParc]. Last modified January 11, 2011. Version 3. Checksum: 16BB1094F4D3513D	FASTA	267	30,307
	10 20 30 40 50 60 MRVAALISGG KDSCYNMMQC IAAGHQIVAL ANLRPAENQV GSDELDSYMY QTVGHHAIDL 70 80 90 100 110 120 YAEAMALPLY RRTIRGRSLD TRQVYTKCEG DEVEDLYELL KLVKEKEEVE GISVGAILSD 130 140 150 160 170 180 YQRIRVENVC KRLNLQPLAY LWQRNQEDLL REMISSNIQA MIIKVAALGL DPDKHLGKTL 190 200 210 220 230 240 DQMEPYLIEL SKKYGVHVCG EGGEYETFTL DCPLFKKKII VDSSEVVIHS ADAFAPVAYL 250 260 RFLELHLEDK VSSVPDNYRT SNYIYNF

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Uterus.
[2]	"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed: 16572171] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Bone marrow and Skin.
[4]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed: 21269460] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK094007 mRNA. Translation: BAC04266.1. AC015994 Genomic DNA. No translation available. AC019288 Genomic DNA. No translation available. BC008485 mRNA. Translation: AAH08485.2. BC066652 mRNA. Translation: AAH66652.1.
IPI	IPI00063121.
RefSeq	NP_542381.1. NM_080650.3.
UniGene	Hs.107196.
3D structure databases
HSSP	HSSP built from PDB template 2D13 based on UniProtKB O58996.
ProteinModelPortal	Q7L8W6.
SMR	Q7L8W6. Positions 1-250.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7L8W6.
PTM databases
PhosphoSite	Q7L8W6.
Polymorphism databases
DMDM	143955280.
Proteomic databases
PRIDE	Q7L8W6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000256538; ENSP00000256538; ENSG00000134146.
GeneID	89978.
KEGG	hsa:89978.
UCSC	uc001zja.1. human.
Organism-specific databases
CTD	89978.
GeneCards	GC15M035663.
HGNC	HGNC:30543. ATPBD4.
HPA	HPA042976.
neXtProt	NX_Q7L8W6.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG12121.
GeneTree	ENSGT00420000029820.
HOGENOM	HBG726495.
HOVERGEN	HBG100452.
InParanoid	Q7L8W6.
OMA	LDESWLG.
OrthoDB	EOG495ZRT.
PhylomeDB	Q7L8W6.
Gene expression databases
ArrayExpress	Q7L8W6.
Bgee	Q7L8W6.
CleanEx	HS_ATPBD4.
Genevestigator	Q7L8W6.
Family and domain databases
InterPro	IPR002761. DUF71_ATP-bd_dom. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01902. ATP_bind_4. 1 hit. [Graphical view]
TIGRFAMs	TIGR00290. MJ0570_dom. 1 hit.
ProtoNet	Search...
Other
NextBio	76470.

Entry information

Entry name

ATBD4_HUMAN

Accession

Primary (citable) accession number: Q7L8W6
Secondary accession number(s): Q96HJ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2007
Last sequence update:	January 11, 2011
Last modified:	January 25, 2012
This is version 61 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.