##gff-version 3
Q7L5A8	UniProtKB	Chain	1	372	.	.	.	ID=PRO_0000312349;Note=Fatty acid 2-hydroxylase	
Q7L5A8	UniProtKB	Transmembrane	168	188	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7L5A8	UniProtKB	Transmembrane	213	233	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7L5A8	UniProtKB	Transmembrane	268	288	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7L5A8	UniProtKB	Transmembrane	290	310	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7L5A8	UniProtKB	Domain	8	86	.	.	.	Note=Cytochrome b5 heme-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00279	
Q7L5A8	UniProtKB	Domain	219	361	.	.	.	Note=Fatty acid hydroxylase;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7L5A8	UniProtKB	Binding site	43	43	.	.	.	Note=Axial binding residue;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00279	
Q7L5A8	UniProtKB	Binding site	69	69	.	.	.	Note=Axial binding residue;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00279	
Q7L5A8	UniProtKB	Binding site	234	234	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	239	239	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	257	257	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	260	260	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	261	261	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	315	315	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	319	319	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	336	336	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	339	339	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Binding site	340	340	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q03529	
Q7L5A8	UniProtKB	Alternative sequence	1	213	.	.	.	ID=VSP_056135;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q7L5A8	UniProtKB	Natural variant	35	35	.	.	.	ID=VAR_054893;Note=In SPG35%3B patients present spastic paraparesis associated with leukodystrophy and dystonia. D->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19068277;Dbxref=dbSNP:rs121918217,PMID:19068277	
Q7L5A8	UniProtKB	Natural variant	53	58	.	.	.	ID=VAR_064620;Note=In SPG35%3B significantly reduced enzymatic function. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20104589;Dbxref=PMID:20104589	
Q7L5A8	UniProtKB	Natural variant	97	97	.	.	.	ID=VAR_037503;Note=P->A;Dbxref=dbSNP:rs35874850	
Q7L5A8	UniProtKB	Natural variant	154	154	.	.	.	ID=VAR_065245;Note=In SPG35. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20853438;Dbxref=dbSNP:rs387907040,PMID:20853438	
Q7L5A8	UniProtKB	Natural variant	235	235	.	.	.	ID=VAR_064621;Note=In SPG35%3B significantly reduced enzymatic function. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20104589;Dbxref=dbSNP:rs387907039,PMID:20104589	
Q7L5A8	UniProtKB	Sequence conflict	184	184	.	.	.	Note=S->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q7L5A8	UniProtKB	Sequence conflict	356	356	.	.	.	Note=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305