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Q7L513

- FCRLA_HUMAN

UniProt

Q7L513 - FCRLA_HUMAN

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Protein

Fc receptor-like A

Gene

FCRLA

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

May be implicated in B-cell differentiation and lymphomagenesis.2 Publications

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Differentiation

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Fc receptor-like A
Alternative name(s):
Fc receptor homolog expressed in B-cells
Fc receptor-like and mucin-like protein 1
Fc receptor-like protein
Fc receptor-related protein X
Short name:
FcRX
Gene namesi
Name:FCRLA
Synonyms:FCRL, FCRL1, FCRLM1, FCRX, FREB
ORF Names:UNQ291/PRO329
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:18504. FCRLA.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162388180.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 27271 PublicationAdd
BLAST
Chaini28 – 359332Fc receptor-like APRO_0000227935Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi99 ↔ 143PROSITE-ProRule annotation
Disulfide bondi192 ↔ 240PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiQ7L513.
PaxDbiQ7L513.
PRIDEiQ7L513.

PTM databases

PhosphoSiteiQ7L513.

Expressioni

Tissue specificityi

Expressed specifically in primary and secondary lymphoid tissues like lymph node, spleen and tonsil. Specifically expressed in B-cells with a high level in normal germinal center B-cells, centroblasts and in a subset of diffuse large B-cell lymphomas. Highly expressed in bone marrow B-cells and weakly in earlier B lineage cells. Expressed in pre-germinal and germinal center B-cells in secondary lymphoid tissues. Also expressed in melanoma and melanocytes.4 Publications

Gene expression databases

BgeeiQ7L513.
CleanExiHS_FCRL1.
ExpressionAtlasiQ7L513. baseline and differential.
GenevestigatoriQ7L513.

Organism-specific databases

HPAiCAB016545.

Interactioni

Subunit structurei

Monomer or homodimer; disulfide-linked.

Protein-protein interaction databases

BioGridi124282. 1 interaction.
IntActiQ7L513. 4 interactions.

Structurei

Secondary structure

1
359
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi173 – 1786Combined sources
Beta strandi188 – 1936Combined sources
Beta strandi206 – 2116Combined sources
Beta strandi214 – 2218Combined sources
Beta strandi224 – 2296Combined sources
Helixi232 – 2343Combined sources
Beta strandi236 – 2438Combined sources
Beta strandi247 – 2526Combined sources
Beta strandi256 – 2583Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HWNX-ray2.01A169-264[»]
ProteinModelPortaliQ7L513.
SMRiQ7L513. Positions 32-262.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 15990Ig-like C2-type 1Add
BLAST
Domaini170 – 25788Ig-like C2-type 2Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi269 – 31547Pro-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

eggNOGiNOG69552.
GeneTreeiENSGT00760000119130.
HOVERGENiHBG059243.
InParanoidiQ7L513.
OrthoDBiEOG7H1JM6.
PhylomeDBiQ7L513.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequences (15)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 15 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q7L513-1) [UniParc]FASTAAdd to Basket

Also known as: FCRLa

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKLGCVLMAW ALYLSLGVLW VAQMLLAASF ETLQCEGPVC TEESSCHTED
60 70 80 90 100
DLTDAREAGF QVKAYTFSEP FHLIVSYDWL ILQGPAKPVF EGDLLVLRCQ
110 120 130 140 150
AWQDWPLTQV TFYRDGSALG PPGPNREFSI TVVQKADSGH YHCSGIFQSP
160 170 180 190 200
GPGIPETASV VAITVQELFP APILRAVPSA EPQAGSPMTL SCQTKLPLQR
210 220 230 240 250
SAARLLFSFY KDGRIVQSRG LSSEFQIPTA SEDHSGSYWC EAATEDNQVW
260 270 280 290 300
KQSPQLEIRV QGASSSAAPP TLNPAPQKSA APGTAPEEAP GPLPPPPTPS
310 320 330 340 350
SEDPGFSSPL GMPDPHLYHQ MGLLLKHMQD VRVLLGHLLM ELRELSGHRK

PGTTKATAE
Length:359
Mass (Da):38,927
Last modified:March 21, 2006 - v2
Checksum:i76821DADB121499F
GO
Isoform 2 (identifier: Q7L513-2) [UniParc]FASTAAdd to Basket

Also known as: FCRLa1

The sequence of this isoform differs from the canonical sequence as follows:
     28-28: A → AGCHAAA

Show »
Length:365
Mass (Da):39,438
Checksum:iCCE4864CD4C54490
GO
Isoform 3 (identifier: Q7L513-3) [UniParc]FASTAAdd to Basket

Also known as: FCRLb

The sequence of this isoform differs from the canonical sequence as follows:
     78-166: Missing.

Show »
Length:270
Mass (Da):29,281
Checksum:i5C8206F2AD581FEF
GO
Isoform 4 (identifier: Q7L513-4) [UniParc]FASTAAdd to Basket

Also known as: FCRLc1

The sequence of this isoform differs from the canonical sequence as follows:
     29-166: SFETLQCEGP...TASVVAITVQ → GCHA

Show »
Length:225
Mass (Da):24,149
Checksum:i004B85CFCA2232C8
GO
Isoform 5 (identifier: Q7L513-5) [UniParc]FASTAAdd to Basket

Also known as: FCRLc2

The sequence of this isoform differs from the canonical sequence as follows:
     27-166: Missing.

Show »
Length:219
Mass (Da):23,638
Checksum:i7221B95E05E01932
GO
Isoform 6 (identifier: Q7L513-6) [UniParc]FASTAAdd to Basket

Also known as: FCRLd

The sequence of this isoform differs from the canonical sequence as follows:
     78-261: Missing.

Show »
Length:175
Mass (Da):18,719
Checksum:i1EB948BC1FD4EB45
GO
Isoform 7 (identifier: Q7L513-7) [UniParc]FASTAAdd to Basket

Also known as: FCRLe

The sequence of this isoform differs from the canonical sequence as follows:
     27-261: Missing.

Show »
Length:124
Mass (Da):13,076
Checksum:iDA62850F76758F70
GO
Isoform 8 (identifier: Q7L513-8) [UniParc]FASTAAdd to Basket

Also known as: FCRLf

The sequence of this isoform differs from the canonical sequence as follows:
     167-261: Missing.

Show »
Length:264
Mass (Da):28,365
Checksum:iC3FC5FC795C82CD0
GO
Isoform 9 (identifier: Q7L513-9) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM

Show »
Length:376
Mass (Da):40,655
Checksum:iA8EEAF71347126DE
GO
Isoform 10 (identifier: Q7L513-10) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     28-28: A → AGCHAAA

Note: No experimental confirmation available.

Show »
Length:382
Mass (Da):41,166
Checksum:i3A20194B87382AFC
GO
Isoform 11 (identifier: Q7L513-11) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     29-166: SFETLQCEGP...TASVVAITVQ → GCHA

Note: No experimental confirmation available.

Show »
Length:242
Mass (Da):25,877
Checksum:iFCFE2BFCD6328F00
GO
Isoform 12 (identifier: Q7L513-12) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     78-166: Missing.

Note: No experimental confirmation available.

Show »
Length:287
Mass (Da):31,009
Checksum:iC3F802DDA6EAF181
GO
Isoform 13 (identifier: Q7L513-13) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     78-261: Missing.

Note: No experimental confirmation available.

Show »
Length:192
Mass (Da):20,448
Checksum:iB0CDC702FB3B4F09
GO
Isoform 14 (identifier: Q7L513-14) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     27-166: Missing.

Note: No experimental confirmation available.

Show »
Length:236
Mass (Da):25,366
Checksum:i3FE90660ECE2455F
GO
Isoform 15 (identifier: Q7L513-15) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLKKISVGVAGDLNTVTM
     27-261: Missing.

Note: No experimental confirmation available.

Show »
Length:141
Mass (Da):14,804
Checksum:iA481C1809EA0F67F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti265 – 2651S → N in AAL23904. (PubMed:11754007)Curated
Sequence conflicti308 – 3081S → P in AAL23903. (PubMed:11754007)Curated
Sequence conflicti317 – 3171L → P in AAL27307. (PubMed:11754007)Curated
Sequence conflicti343 – 3431R → G in AAL23905. (PubMed:11754007)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti349 – 3491R → Q.6 Publications
Corresponds to variant rs11746 [ dbSNP | Ensembl ].
VAR_025646

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11M → MLKKISVGVAGDLNTVTM in isoform 9, isoform 10, isoform 11, isoform 12, isoform 13, isoform 14 and isoform 15. 3 PublicationsVSP_038297
Alternative sequencei27 – 261235Missing in isoform 7 and isoform 15. 2 PublicationsVSP_017603Add
BLAST
Alternative sequencei27 – 166140Missing in isoform 5 and isoform 14. 2 PublicationsVSP_017604Add
BLAST
Alternative sequencei28 – 281A → AGCHAAA in isoform 2 and isoform 10. 1 PublicationVSP_017605
Alternative sequencei29 – 166138SFETL…AITVQ → GCHA in isoform 4 and isoform 11. 1 PublicationVSP_017606Add
BLAST
Alternative sequencei78 – 261184Missing in isoform 6 and isoform 13. 2 PublicationsVSP_017607Add
BLAST
Alternative sequencei78 – 16689Missing in isoform 3 and isoform 12. 2 PublicationsVSP_017608Add
BLAST
Alternative sequencei167 – 26195Missing in isoform 8. 1 PublicationVSP_017609Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329489 mRNA. Translation: AAL23899.1.
AF329491 mRNA. Translation: AAL23901.1.
AF329493 mRNA. Translation: AAL23903.1.
AF329494 mRNA. Translation: AAL23904.1.
AF329495 mRNA. Translation: AAL23905.1.
AF390036 mRNA. Translation: AAL27307.1.
AF426461 mRNA. Translation: AAL58111.1.
AF531423 mRNA. Translation: AAM97591.1.
AY091642 mRNA. Translation: AAM13980.2.
EF064729 Genomic DNA. Translation: ABK41912.1.
AY358348 mRNA. Translation: AAQ88714.1.
AL359541 Genomic DNA. No translation available.
CH471067 Genomic DNA. Translation: EAW90683.1.
CH471067 Genomic DNA. Translation: EAW90684.1.
CH471067 Genomic DNA. Translation: EAW90685.1.
BC006521 mRNA. Translation: AAH06521.2.
CCDSiCCDS30926.1. [Q7L513-9]
CCDS53415.1. [Q7L513-10]
CCDS53416.1. [Q7L513-11]
CCDS53417.1. [Q7L513-12]
CCDS53418.1. [Q7L513-13]
CCDS53419.1. [Q7L513-14]
CCDS53420.1. [Q7L513-15]
RefSeqiNP_001171795.1. NM_001184866.1. [Q7L513-10]
NP_001171796.1. NM_001184867.1. [Q7L513-12]
NP_001171799.1. NM_001184870.1. [Q7L513-11]
NP_001171800.1. NM_001184871.1. [Q7L513-15]
NP_001171801.1. NM_001184872.1. [Q7L513-14]
NP_001171802.1. NM_001184873.1. [Q7L513-13]
NP_116127.3. NM_032738.3. [Q7L513-9]
UniGeneiHs.266331.

Genome annotation databases

EnsembliENST00000236938; ENSP00000236938; ENSG00000132185. [Q7L513-9]
ENST00000294796; ENSP00000294796; ENSG00000132185. [Q7L513-4]
ENST00000309691; ENSP00000309596; ENSG00000132185. [Q7L513-3]
ENST00000349527; ENSP00000294798; ENSG00000132185. [Q7L513-8]
ENST00000350710; ENSP00000344808; ENSG00000132185. [Q7L513-15]
ENST00000367949; ENSP00000356926; ENSG00000132185. [Q7L513-13]
ENST00000367953; ENSP00000356930; ENSG00000132185. [Q7L513-2]
ENST00000367957; ENSP00000356934; ENSG00000132185. [Q7L513-14]
ENST00000367959; ENSP00000356936; ENSG00000132185. [Q7L513-10]
ENST00000540521; ENSP00000442870; ENSG00000132185. [Q7L513-11]
ENST00000546024; ENSP00000439838; ENSG00000132185. [Q7L513-12]
GeneIDi84824.
KEGGihsa:84824.
UCSCiuc001gbd.3. human. [Q7L513-9]
uc001gbf.3. human.
uc031prb.1. human. [Q7L513-1]

Polymorphism databases

DMDMi90101291.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329489 mRNA. Translation: AAL23899.1 .
AF329491 mRNA. Translation: AAL23901.1 .
AF329493 mRNA. Translation: AAL23903.1 .
AF329494 mRNA. Translation: AAL23904.1 .
AF329495 mRNA. Translation: AAL23905.1 .
AF390036 mRNA. Translation: AAL27307.1 .
AF426461 mRNA. Translation: AAL58111.1 .
AF531423 mRNA. Translation: AAM97591.1 .
AY091642 mRNA. Translation: AAM13980.2 .
EF064729 Genomic DNA. Translation: ABK41912.1 .
AY358348 mRNA. Translation: AAQ88714.1 .
AL359541 Genomic DNA. No translation available.
CH471067 Genomic DNA. Translation: EAW90683.1 .
CH471067 Genomic DNA. Translation: EAW90684.1 .
CH471067 Genomic DNA. Translation: EAW90685.1 .
BC006521 mRNA. Translation: AAH06521.2 .
CCDSi CCDS30926.1. [Q7L513-9 ]
CCDS53415.1. [Q7L513-10 ]
CCDS53416.1. [Q7L513-11 ]
CCDS53417.1. [Q7L513-12 ]
CCDS53418.1. [Q7L513-13 ]
CCDS53419.1. [Q7L513-14 ]
CCDS53420.1. [Q7L513-15 ]
RefSeqi NP_001171795.1. NM_001184866.1. [Q7L513-10 ]
NP_001171796.1. NM_001184867.1. [Q7L513-12 ]
NP_001171799.1. NM_001184870.1. [Q7L513-11 ]
NP_001171800.1. NM_001184871.1. [Q7L513-15 ]
NP_001171801.1. NM_001184872.1. [Q7L513-14 ]
NP_001171802.1. NM_001184873.1. [Q7L513-13 ]
NP_116127.3. NM_032738.3. [Q7L513-9 ]
UniGenei Hs.266331.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HWN X-ray 2.01 A 169-264 [» ]
ProteinModelPortali Q7L513.
SMRi Q7L513. Positions 32-262.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 124282. 1 interaction.
IntActi Q7L513. 4 interactions.

Protein family/group databases

MEROPSi I43.001.

PTM databases

PhosphoSitei Q7L513.

Polymorphism databases

DMDMi 90101291.

Proteomic databases

MaxQBi Q7L513.
PaxDbi Q7L513.
PRIDEi Q7L513.

Protocols and materials databases

DNASUi 84824.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000236938 ; ENSP00000236938 ; ENSG00000132185 . [Q7L513-9 ]
ENST00000294796 ; ENSP00000294796 ; ENSG00000132185 . [Q7L513-4 ]
ENST00000309691 ; ENSP00000309596 ; ENSG00000132185 . [Q7L513-3 ]
ENST00000349527 ; ENSP00000294798 ; ENSG00000132185 . [Q7L513-8 ]
ENST00000350710 ; ENSP00000344808 ; ENSG00000132185 . [Q7L513-15 ]
ENST00000367949 ; ENSP00000356926 ; ENSG00000132185 . [Q7L513-13 ]
ENST00000367953 ; ENSP00000356930 ; ENSG00000132185 . [Q7L513-2 ]
ENST00000367957 ; ENSP00000356934 ; ENSG00000132185 . [Q7L513-14 ]
ENST00000367959 ; ENSP00000356936 ; ENSG00000132185 . [Q7L513-10 ]
ENST00000540521 ; ENSP00000442870 ; ENSG00000132185 . [Q7L513-11 ]
ENST00000546024 ; ENSP00000439838 ; ENSG00000132185 . [Q7L513-12 ]
GeneIDi 84824.
KEGGi hsa:84824.
UCSCi uc001gbd.3. human. [Q7L513-9 ]
uc001gbf.3. human.
uc031prb.1. human. [Q7L513-1 ]

Organism-specific databases

CTDi 84824.
GeneCardsi GC01P161676.
H-InvDB HIX0001250.
HGNCi HGNC:18504. FCRLA.
HPAi CAB016545.
MIMi 606891. gene.
neXtProti NX_Q7L513.
PharmGKBi PA162388180.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG69552.
GeneTreei ENSGT00760000119130.
HOVERGENi HBG059243.
InParanoidi Q7L513.
OrthoDBi EOG7H1JM6.
PhylomeDBi Q7L513.

Miscellaneous databases

ChiTaRSi FCRLA. human.
GeneWikii FCRLA.
GenomeRNAii 84824.
NextBioi 75032.
PROi Q7L513.
SOURCEi Search...

Gene expression databases

Bgeei Q7L513.
CleanExi HS_FCRL1.
ExpressionAtlasi Q7L513. baseline and differential.
Genevestigatori Q7L513.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view ]
SMARTi SM00409. IG. 2 hits.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "FCRL, a novel member of the leukocyte Fc receptor family possesses unique structural features."
    Mechetina L.V., Najakshin A.M., Volkova O.Y., Guselnikov S.V., Faizulin R.Z., Alabyev B.Y., Chikaev N.A., Vinogradova M.S., Taranin A.V.
    Eur. J. Immunol. 32:87-96(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 3; 4; 5; 6 AND 7), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANT GLN-349.
    Tissue: Lymph, Melanocyte and Tonsil.
  2. "An unusual Fc receptor-related protein expressed in human centroblasts."
    Facchetti F., Cella M., Festa S., Fremont D.H., Colonna M.
    Proc. Natl. Acad. Sci. U.S.A. 99:3776-3781(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 9), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANT GLN-349.
  3. "Definition of an Fc receptor-related gene (FcRX) expressed in human and mouse B cells."
    Davis R.S., Li H., Chen C.-C., Wang Y.-H., Cooper M.D., Burrows P.D.
    Int. Immunol. 14:1075-1083(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 9), TISSUE SPECIFICITY, VARIANT GLN-349.
  4. "Novel melanoma antigen, FCRL/FREB, identified by cDNA profile comparison using DNA chip are immunogenic in multiple melanoma patients."
    Inozume T., Matsuzaki Y., Kurihara S., Fujita T., Yamamoto A., Aburatani H., Shimada S., Kawakami Y.
    Int. J. Cancer 114:283-290(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 3; 5; 6; 7 AND 8), TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
    Tissue: Melanocyte.
  5. Guselnikov S., Najakshin A.M.
    Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT GLN-349.
    Tissue: Tonsil.
  6. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 9), VARIANT GLN-349.
    Tissue: Lymph and Tonsil.
  8. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLN-349.
    Tissue: Skin.
  11. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
    Zhang Z., Henzel W.J.
    Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 28-42.
  12. Bienvenut W.V.
    Submitted (JUN-2005) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 88-98; 252-259 AND 333-353, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: B-cell lymphoma.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiFCRLA_HUMAN
AccessioniPrimary (citable) accession number: Q7L513
Secondary accession number(s): A0N0M1
, A6NC03, A6NL20, F5H720, F8W743, G3V1J2, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXA4, Q5VXB0, Q5VXB1, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: March 21, 2006
Last modified: November 26, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3