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Protein

Protein ARMCX6

Gene

ARMCX6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ARMCX6
Gene namesi
Name:ARMCX6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:26094. ARMCX6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134869551.

Polymorphism and mutation databases

BioMutaiARMCX6.
DMDMi74749890.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300Protein ARMCX6PRO_0000191374Add
BLAST

Proteomic databases

PaxDbiQ7L4S7.
PRIDEiQ7L4S7.

Expressioni

Gene expression databases

BgeeiQ7L4S7.
CleanExiHS_ARMCX6.
GenevisibleiQ7L4S7. HS.

Organism-specific databases

HPAiHPA043030.
HPA048125.

Structurei

3D structure databases

ProteinModelPortaliQ7L4S7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG38789.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG097741.
InParanoidiQ7L4S7.
OMAiDGDWTEP.
OrthoDBiEOG70PBZ0.
PhylomeDBiQ7L4S7.
TreeFamiTF335652.

Family and domain databases

InterProiIPR006911. ARM-rpt_dom.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7L4S7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRAREVGWM AAGLMIGAGA CYCVYKLTIG RDDSEKLEEE GEEEWDDDQE
60 70 80 90 100
LDEEEPDIWF DFETMARPWT EDGDWTEPGA PGGTEDRPSG GGKANRAHPI
110 120 130 140 150
KQRPFPYEHK NTWSAQNCKN GSCVLDLSKC LFIQGKLLFA EPKDAGFPFS
160 170 180 190 200
QDINSHLASL SMARNTSPTP DPTVREALCA PDNLNASIES QGQIKMYINE
210 220 230 240 250
VCRETVSRCC NSFLQQAGLN LLISMTVINN MLAKSASDLK FPLISEGSGC
260 270 280 290 300
AKVQVLKPLM GLSEKPVLAG ELVGAQMLFS FMSLFIRNGN REILLETPAP
Length:300
Mass (Da):33,019
Last modified:July 5, 2004 - v1
Checksum:i44393DA4160D88A1
GO

Sequence cautioni

The sequence BAA91387.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121883 Genomic DNA. Translation: CAI42938.1.
BC007677 mRNA. Translation: AAH07677.2.
AK000818 mRNA. Translation: BAA91387.1. Different initiation.
CCDSiCCDS14488.1.
RefSeqiNP_001009584.1. NM_001009584.1.
NP_001171697.1. NM_001184768.1.
NP_061880.2. NM_019007.3.
UniGeneiHs.83530.

Genome annotation databases

EnsembliENST00000361910; ENSP00000354708; ENSG00000198960.
ENST00000538627; ENSP00000440648; ENSG00000198960.
ENST00000539247; ENSP00000444537; ENSG00000198960.
GeneIDi54470.
KEGGihsa:54470.
UCSCiuc004ehx.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121883 Genomic DNA. Translation: CAI42938.1.
BC007677 mRNA. Translation: AAH07677.2.
AK000818 mRNA. Translation: BAA91387.1. Different initiation.
CCDSiCCDS14488.1.
RefSeqiNP_001009584.1. NM_001009584.1.
NP_001171697.1. NM_001184768.1.
NP_061880.2. NM_019007.3.
UniGeneiHs.83530.

3D structure databases

ProteinModelPortaliQ7L4S7.
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

BioMutaiARMCX6.
DMDMi74749890.

Proteomic databases

PaxDbiQ7L4S7.
PRIDEiQ7L4S7.

Protocols and materials databases

DNASUi54470.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361910; ENSP00000354708; ENSG00000198960.
ENST00000538627; ENSP00000440648; ENSG00000198960.
ENST00000539247; ENSP00000444537; ENSG00000198960.
GeneIDi54470.
KEGGihsa:54470.
UCSCiuc004ehx.3. human.

Organism-specific databases

CTDi54470.
GeneCardsiGC0XM100870.
H-InvDBHIX0176760.
HGNCiHGNC:26094. ARMCX6.
HPAiHPA043030.
HPA048125.
neXtProtiNX_Q7L4S7.
PharmGKBiPA134869551.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG38789.
GeneTreeiENSGT00550000074488.
HOGENOMiHOG000231611.
HOVERGENiHBG097741.
InParanoidiQ7L4S7.
OMAiDGDWTEP.
OrthoDBiEOG70PBZ0.
PhylomeDBiQ7L4S7.
TreeFamiTF335652.

Miscellaneous databases

ChiTaRSiARMCX6. human.
GeneWikiiARMCX6.
GenomeRNAii54470.
NextBioi56762.
PROiQ7L4S7.

Gene expression databases

BgeeiQ7L4S7.
CleanExiHS_ARMCX6.
GenevisibleiQ7L4S7. HS.

Family and domain databases

InterProiIPR006911. ARM-rpt_dom.
[Graphical view]
PfamiPF04826. Arm_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Uterus.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 26-300.
    Tissue: Adipose tissue.

Entry informationi

Entry nameiARMX6_HUMAN
AccessioniPrimary (citable) accession number: Q7L4S7
Secondary accession number(s): Q9NWJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 5, 2004
Last modified: June 24, 2015
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.