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Protein
Submitted name:

KRT8 protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
KRT8 proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Intermediate filamentUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ7L4M3.
PRIDEiQ7L4M3.

Expressioni

Gene expression databases

BgeeiQ7L4M3.

Interactioni

Protein-protein interaction databases

IntActiQ7L4M3. 1 interaction.
STRINGi9606.ENSP00000293308.

Structurei

3D structure databases

ProteinModelPortaliQ7L4M3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili3 – 3028Sequence analysisAdd
BLAST
Coiled coili96 – 17681Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the intermediate filament family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IG4R. Eukaryota.
ENOG410YY6B. LUCA.
HOVERGENiHBG013015.

Family and domain databases

InterProiIPR001664. IF.
IPR018039. Intermediate_filament_CS.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR23239. PTHR23239. 2 hits.
PfamiPF00038. Filament. 1 hit.
[Graphical view]
SMARTiSM01391. Filament. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
PROSITEiPS00226. IF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7L4M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKVELESRL EGLTDEINFL RQLYEEEIRE LQSQISDTSV VLSMDNSRSL
60 70 80 90 100
DMDSIIAEVK AQYEDIANRS RAEAESMYQI KYEELQSLAG KHGDDLRRTK
110 120 130 140 150
TEISEMNRNI SRLQAEIEGL KGQRASLEAA IADAEQRGEL AIKDANAKLS
160 170 180 190 200
ELEAALQRAK QDMARQLREY QELMNVKLAL DIEIATYRKL LEGEESRLES
210 220 230 240 250
GMQNMSIHTK TTSGYAGGLS SAYGGLTSPG LSYSLGSSFG SGAGSSSFSR
260 270
TSSSRAVVVK KIETRDGKLV SESSDVLPK
Length:279
Mass (Da):30,820
Last modified:May 24, 2005 - v1
Checksum:iD9B2EB27FD985629
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC008200 mRNA. Translation: AAH08200.1.
RefSeqiNP_001243211.1. NM_001256282.1.
UniGeneiHs.533782.
Hs.708445.

Genome annotation databases

GeneIDi3856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC008200 mRNA. Translation: AAH08200.1.
RefSeqiNP_001243211.1. NM_001256282.1.
UniGeneiHs.533782.
Hs.708445.

3D structure databases

ProteinModelPortaliQ7L4M3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ7L4M3. 1 interaction.
STRINGi9606.ENSP00000293308.

Proteomic databases

PaxDbiQ7L4M3.
PRIDEiQ7L4M3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3856.

Organism-specific databases

CTDi3856.

Phylogenomic databases

eggNOGiENOG410IG4R. Eukaryota.
ENOG410YY6B. LUCA.
HOVERGENiHBG013015.

Miscellaneous databases

GenomeRNAii3856.

Gene expression databases

BgeeiQ7L4M3.

Family and domain databases

InterProiIPR001664. IF.
IPR018039. Intermediate_filament_CS.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR23239. PTHR23239. 2 hits.
PfamiPF00038. Filament. 1 hit.
[Graphical view]
SMARTiSM01391. Filament. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
PROSITEiPS00226. IF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PlacentaImported.

Entry informationi

Entry nameiQ7L4M3_HUMAN
AccessioniPrimary (citable) accession number: Q7L4M3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 8, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.