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Q7L2E3

- DHX30_HUMAN

UniProt

Q7L2E3 - DHX30_HUMAN

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Protein

Putative ATP-dependent RNA helicase DHX30

Gene

DHX30

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA.By similarity1 Publication

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi457 – 4648ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent helicase activity Source: InterPro
  3. chromatin binding Source: UniProtKB
  4. double-stranded RNA binding Source: MGI
  5. poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ATP-dependent RNA helicase DHX30 (EC:3.6.4.13)
Alternative name(s):
DEAH box protein 30
Gene namesi
Name:DHX30
Synonyms:DDX30, KIAA0890
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:16716. DHX30.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. mitochondrial nucleoid Source: BHF-UCL
  3. mitochondrion Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Mitochondrion, Mitochondrion nucleoid

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27217.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11941194Putative ATP-dependent RNA helicase DHX30PRO_0000245538Add
BLAST

Post-translational modificationi

Isoform 2 is phosphorylated on Ser-15.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ7L2E3.
PaxDbiQ7L2E3.
PRIDEiQ7L2E3.

PTM databases

PhosphoSiteiQ7L2E3.

Expressioni

Gene expression databases

BgeeiQ7L2E3.
CleanExiHS_DHX30.
ExpressionAtlasiQ7L2E3. baseline and differential.
GenevestigatoriQ7L2E3.

Organism-specific databases

HPAiHPA034805.
HPA034806.

Interactioni

Subunit structurei

Identified in a complex with TFAM and SSBP1. Interacts with AGO1 and AGO2. Interacts (via N-terminus) with ZC3HAV1 (via N-terminal domain) in an RNA-independent manner (By similarity).By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
CDK9P507505EBI-1211456,EBI-1383449
DHX58Q96C102EBI-1211456,EBI-744193
EIF2AK2P195253EBI-1211456,EBI-640775
HDAC1Q135473EBI-1211456,EBI-301834
HDAC3O153793EBI-1211456,EBI-607682
MYBBP1AQ9BQG03EBI-1211456,EBI-676973
NCOR1O753763EBI-1211456,EBI-347233
NR2E3Q9Y5X45EBI-1211456,EBI-7216962
OAS3Q9Y6K52EBI-1211456,EBI-6115729
RBBP4Q090283EBI-1211456,EBI-620823
RBBP7Q165764EBI-1211456,EBI-352227
RBL1P287494EBI-1211456,EBI-971402
SIN3AQ96ST33EBI-1211456,EBI-347218
TBL3Q127885EBI-1211456,EBI-715766

Protein-protein interaction databases

BioGridi116571. 56 interactions.
IntActiQ7L2E3. 40 interactions.
MINTiMINT-1186537.
STRINGi9606.ENSP00000392601.

Structurei

Secondary structure

1
1194
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni47 – 493Combined sources
Helixi53 – 6412Combined sources
Helixi67 – 737Combined sources
Beta strandi74 – 785Combined sources
Beta strandi81 – 9111Combined sources
Beta strandi93 – 953Combined sources
Beta strandi97 – 1059Combined sources
Helixi106 – 12419Combined sources
Helixi136 – 1449Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2DB2NMR-A42-147[»]
ProteinModelPortaliQ7L2E3.
SMRiQ7L2E3. Positions 44-152, 239-336, 427-981.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7L2E3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 12169DRBMAdd
BLAST
Domaini444 – 612169Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini654 – 827174Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi559 – 5624DEAH box

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi188 – 19912Poly-GluAdd
BLAST

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG1643.
GeneTreeiENSGT00760000119189.
HOGENOMiHOG000112212.
HOVERGENiHBG081437.
InParanoidiQ7L2E3.
KOiK13185.
OMAiHKEERYD.
OrthoDBiEOG7JX33D.
PhylomeDBiQ7L2E3.
TreeFamiTF352030.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Note: Additional isoforms seem to exist.

Isoform 1 (identifier: Q7L2E3-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFSLDSFRKD RAQHRQRQCK LPPPRLPPMC VNPTPGGTIS RASRDLLKEF
60 70 80 90 100
PQPKNLLNSV IGRALGISHA KDKLVYVHTN GPKKKKVTLH IKWPKSVEVE
110 120 130 140 150
GYGSKKIDAE RQAAAAACQL FKGWGLLGPR NELFDAAKYR VLADRFGSPA
160 170 180 190 200
DSWWRPEPTM PPTSWRQLNP ESIRPGGPGG LSRSLGREEE EDEEEELEEG
210 220 230 240 250
TIDVTDFLSM TQQDSHAPLR DSRGSSFEMT DDDSAIRALT QFPLPKNLLA
260 270 280 290 300
KVIQIATSSS TAKNLMQFHT VGTKTKLSTL TLLWPCPMTF VAKGRRKAEA
310 320 330 340 350
ENKAAALACK KLKSLGLVDR NNEPLTHAMY NLASLRELGE TQRRPCTIQV
360 370 380 390 400
PEPILRKIET FLNHYPVESS WIAPELRLQS DDILPLGKDS GPLSDPITGK
410 420 430 440 450
PYVPLLEAEE VRLSQSLLEL WRRRGPVWQE APQLPVDPHR DTILNAIEQH
460 470 480 490 500
PVVVISGDTG CGKTTRIPQL LLERYVTEGR GARCNVIITQ PRRISAVSVA
510 520 530 540 550
QRVSHELGPS LRRNVGFQVR LESKPPSRGG ALLFCTVGIL LRKLQSNPSL
560 570 580 590 600
EGVSHVIVDE VHERDVNTDF LLILLKGLQR LNPALRLVLM SATGDNERFS
610 620 630 640 650
RYFGGCPVIK VPGFMYPVKE HYLEDILAKL GKHQYLHRHR HHESEDECAL
660 670 680 690 700
DLDLVTDLVL HIDARGEPGG ILCFLPGWQE IKGVQQRLQE ALGMHESKYL
710 720 730 740 750
ILPVHSNIPM MDQKAIFQQP PVGVRKIVLA TNIAETSITI NDIVHVVDSG
760 770 780 790 800
LHKEERYDLK TKVSCLETVW VSRANVIQRR GRAGRCQSGF AYHLFPRSRL
810 820 830 840 850
EKMVPFQVPE ILRTPLENLV LQAKIHMPEK TAVEFLSKAV DSPNIKAVDE
860 870 880 890 900
AVILLQEIGV LDQREYLTTL GQRLAHISTD PRLAKAIVLA AIFRCLHPLL
910 920 930 940 950
VVVSCLTRDP FSSSLQNRAE VDKVKALLSH DSGSDHLAFV RAVAGWEEVL
960 970 980 990 1000
RWQDRSSREN YLEENLLYAP SLRFIHGLIK QFSENIYEAF LVGKPSDCTL
1010 1020 1030 1040 1050
ASAQCNEYSE EEELVKGVLM AGLYPNLIQV RQGKVTRQGK FKPNSVTYRT
1060 1070 1080 1090 1100
KSGNILLHKS TINREATRLR SRWLTYFMAV KSNGSVFVRD SSQVHPLAVL
1110 1120 1130 1140 1150
LLTDGDVHIR DDGRRATISL SDSDLLRLEG DSRTVRLLKE LRRALGRMVE
1160 1170 1180 1190
RSLRSELAAL PPSVQEEHGQ LLALLAELLR GPCGSFDVRK TADD
Length:1,194
Mass (Da):133,938
Last modified:July 5, 2004 - v1
Checksum:i33D9A08799FE7A02
GO
Isoform 2 (identifier: Q7L2E3-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-41: MFSLDSFRKD...NPTPGGTISR → MAAARRLMAL...PGEGDGSLVN

Note: Contains a phosphoserine at position 15.

Show »
Length:1,222
Mass (Da):136,115
Checksum:iBEEE9D1C88DAFCA7
GO
Isoform 3 (identifier: Q7L2E3-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-39: Missing.
     40-41: SR → MA

Show »
Length:1,155
Mass (Da):129,438
Checksum:iD3417B4C609F6360
GO

Sequence cautioni

The sequence BAA74913.2 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAA92071.1 differs from that shown. Reason: Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti557 – 5571I → T in BAF83955. (PubMed:14702039)Curated
Sequence conflicti781 – 7811G → D in BAF83955. (PubMed:14702039)Curated
Sequence conflicti1136 – 11361R → W in AAH14237. (PubMed:15489334)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 4141MFSLD…GTISR → MAAARRLMALAAGISPRLQP LGPRAAGRQGRSRGFSSSCA HPDHTKEAAEAESGMAPGGP GEGDGSLVN in isoform 2. 1 PublicationVSP_022118Add
BLAST
Alternative sequencei1 – 3939Missing in isoform 3. 2 PublicationsVSP_036891Add
BLAST
Alternative sequencei40 – 412SR → MA in isoform 3. 2 PublicationsVSP_036892

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020697 mRNA. Translation: BAA74913.2. Different initiation.
AK002076 mRNA. Translation: BAA92071.1. Sequence problems.
AK291266 mRNA. Translation: BAF83955.1.
BC014237 mRNA. Translation: AAH14237.1.
BC015029 mRNA. Translation: AAH15029.1.
BC020126 mRNA. Translation: AAH20126.1.
BC038417 mRNA. Translation: AAH38417.1.
CCDSiCCDS2759.1. [Q7L2E3-1]
PIRiE56236.
RefSeqiNP_055781.2. NM_014966.3. [Q7L2E3-3]
NP_619520.1. NM_138615.2. [Q7L2E3-1]
XP_006713095.1. XM_006713032.1. [Q7L2E3-2]
UniGeneiHs.517948.

Genome annotation databases

EnsembliENST00000445061; ENSP00000405620; ENSG00000132153. [Q7L2E3-1]
ENST00000446256; ENSP00000392601; ENSG00000132153. [Q7L2E3-1]
ENST00000457607; ENSP00000394682; ENSG00000132153. [Q7L2E3-2]
ENST00000619982; ENSP00000483160; ENSG00000132153. [Q7L2E3-3]
GeneIDi22907.
KEGGihsa:22907.
UCSCiuc003crt.3. human. [Q7L2E3-3]
uc003cru.3. human. [Q7L2E3-1]

Polymorphism databases

DMDMi74758997.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020697 mRNA. Translation: BAA74913.2 . Different initiation.
AK002076 mRNA. Translation: BAA92071.1 . Sequence problems.
AK291266 mRNA. Translation: BAF83955.1 .
BC014237 mRNA. Translation: AAH14237.1 .
BC015029 mRNA. Translation: AAH15029.1 .
BC020126 mRNA. Translation: AAH20126.1 .
BC038417 mRNA. Translation: AAH38417.1 .
CCDSi CCDS2759.1. [Q7L2E3-1 ]
PIRi E56236.
RefSeqi NP_055781.2. NM_014966.3. [Q7L2E3-3 ]
NP_619520.1. NM_138615.2. [Q7L2E3-1 ]
XP_006713095.1. XM_006713032.1. [Q7L2E3-2 ]
UniGenei Hs.517948.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2DB2 NMR - A 42-147 [» ]
ProteinModelPortali Q7L2E3.
SMRi Q7L2E3. Positions 44-152, 239-336, 427-981.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116571. 56 interactions.
IntActi Q7L2E3. 40 interactions.
MINTi MINT-1186537.
STRINGi 9606.ENSP00000392601.

PTM databases

PhosphoSitei Q7L2E3.

Polymorphism databases

DMDMi 74758997.

Proteomic databases

MaxQBi Q7L2E3.
PaxDbi Q7L2E3.
PRIDEi Q7L2E3.

Protocols and materials databases

DNASUi 22907.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000445061 ; ENSP00000405620 ; ENSG00000132153 . [Q7L2E3-1 ]
ENST00000446256 ; ENSP00000392601 ; ENSG00000132153 . [Q7L2E3-1 ]
ENST00000457607 ; ENSP00000394682 ; ENSG00000132153 . [Q7L2E3-2 ]
ENST00000619982 ; ENSP00000483160 ; ENSG00000132153 . [Q7L2E3-3 ]
GeneIDi 22907.
KEGGi hsa:22907.
UCSCi uc003crt.3. human. [Q7L2E3-3 ]
uc003cru.3. human. [Q7L2E3-1 ]

Organism-specific databases

CTDi 22907.
GeneCardsi GC03P047844.
HGNCi HGNC:16716. DHX30.
HPAi HPA034805.
HPA034806.
neXtProti NX_Q7L2E3.
PharmGKBi PA27217.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1643.
GeneTreei ENSGT00760000119189.
HOGENOMi HOG000112212.
HOVERGENi HBG081437.
InParanoidi Q7L2E3.
KOi K13185.
OMAi HKEERYD.
OrthoDBi EOG7JX33D.
PhylomeDBi Q7L2E3.
TreeFami TF352030.

Miscellaneous databases

ChiTaRSi DHX30. human.
EvolutionaryTracei Q7L2E3.
GenomeRNAii 22907.
NextBioi 43571.
PROi Q7L2E3.

Gene expression databases

Bgeei Q7L2E3.
CleanExi HS_DHX30.
ExpressionAtlasi Q7L2E3. baseline and differential.
Genevestigatori Q7L2E3.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
[Graphical view ]
SMARTi SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Tissue: Placenta and Teratocarcinoma.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
    Tissue: Brain, Lymph and Uterus.
  4. "Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane."
    Wang Y., Bogenhagen D.F.
    J. Biol. Chem. 281:25791-25802(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  5. "Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells."
    Hoeck J., Weinmann L., Ender C., Ruedel S., Kremmer E., Raabe M., Urlaub H., Meister G.
    EMBO Rep. 8:1052-1060(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH AGO1 AND AGO2.
  6. "The layered structure of human mitochondrial DNA nucleoids."
    Bogenhagen D.F., Rousseau D., Burke S.
    J. Biol. Chem. 283:3665-3675(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, ASSOCIATION WITH MITOCHONDRIAL DNA, IDENTIFICATION BY MASS SPECTROMETRY.
  7. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
    Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
    J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-15 (ISOFORM 2), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "Solution structure of the double-stranded RNA binding domain in KIAA0890 protein."
    RIKEN structural genomics initiative (RSGI)
    Submitted (JUN-2006) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 42-148.

Entry informationi

Entry nameiDHX30_HUMAN
AccessioniPrimary (citable) accession number: Q7L2E3
Secondary accession number(s): A8K5F1
, O94965, Q7Z753, Q96CH4, Q9NUQ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 5, 2004
Last modified: November 26, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3