Q7L273 (KCTD9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
BTB/POZ domain-containing protein KCTD9

Gene names

Name:

KCTD9

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 BTB (POZ) domain. Contains 1 KHA domain. Contains 3 pentapeptide repeat domains.
Sequence caution	The sequence BAA90904.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Domain	Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein homooligomerization Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 389	389	BTB/POZ domain-containing protein KCTD9		PRO_0000191293
Regions
	Domain	3 – 82	80	KHA
	Domain	89 – 161	73	BTB
	Domain	273 – 297	25	Pentapeptide repeat 1
	Domain	303 – 342	40	Pentapeptide repeat 2
	Domain	343 – 377	35	Pentapeptide repeat 3
Experimental info
	Sequence conflict	12	1	P → R in AAH68518. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q7L273 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 43D4AE36F3B9618F	FASTA	389	42,567
	10 20 30 40 50 60 MRRVTLFLNG SPKNGKVVAV YGTLSDLLSV ASSKLGIKAT SVYNGKGGLI DDIALIRDDD 70 80 90 100 110 120 VLFVCEGEPF IDPQTDSKPP EGLLGFHTDW LTLNVGGRYF TTTRSTLVNK EPDSMLAHMF 130 140 150 160 170 180 KDKGVWGNKQ DHRGAFLIDR SPEYFEPILN YLRHGQLIVN DGINLLGVLE EARFFGIDSL 190 200 210 220 230 240 IEHLEVAIKN SQPPEDHSPI SRKEFVRFLL ATPTKSELRC QGLNFSGADL SRLDLRYINF 250 260 270 280 290 300 KMANLSRCNL AHANLCCANL ERADLSGSVL DCANLQGVKM LCSNAEGASL KLCNFEDPSG 310 320 330 340 350 360 LKANLEGANL KGVDMEGSQM TGINLRVATL KNAKLKNCNL RGATLAGTDL ENCDLSGCDL 370 380 QEANLRGSNV KGAIFEEMLT PLHMSQSVR

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis and Uterus.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 151-389. Tissue: Colon.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC021216 mRNA. Translation: AAH21216.2. BC068518 mRNA. Translation: AAH68518.1. AK000045 mRNA. Translation: BAA90904.1. Different initiation.
IPI	IPI00014825.
RefSeq	NP_060104.2. NM_017634.3.
UniGene	Hs.188763. Hs.72071.
3D structure databases
ProteinModelPortal	Q7L273.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q7L273. 2 interactions.
PTM databases
PhosphoSite	Q7L273.
Polymorphism databases
DMDM	50400921.
Proteomic databases
PaxDb	Q7L273.
PRIDE	Q7L273.
Protocols and materials databases
DNASU	54793.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000221200; ENSP00000221200; ENSG00000104756.
GeneID	54793.
KEGG	hsa:54793.
UCSC	uc003xeo.3. human.
Organism-specific databases
CTD	54793.
GeneCards	GC08M025341.
HGNC	HGNC:22401. KCTD9.
HPA	HPA042468.
neXtProt	NX_Q7L273.
PharmGKB	PA134869993.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG1357.
HOGENOM	HOG000010269.
HOVERGEN	HBG052243.
InParanoid	Q7L273.
OMA	YFTTTRI.
OrthoDB	EOG4BCDN4.
PhylomeDB	Q7L273.
Gene expression databases
Bgee	Q7L273.
CleanEx	HS_KCTD9.
Genevestigator	Q7L273.
GermOnline	ENSG00000104756. Homo sapiens.
Family and domain databases
Gene3D	3.30.710.10. 1 hit.
InterPro	IPR001646. 5peptide_repeat. IPR000210. BTB/POZ-like. IPR011333. BTB/POZ_fold. IPR021789. K_channel_plant. IPR003131. T1-type_BTB. [Graphical view]
Pfam	PF11834. DUF3354. 1 hit. PF02214. K_tetra. 1 hit. PF00805. Pentapeptide. 2 hits. [Graphical view]
SMART	SM00225. BTB. 1 hit. [Graphical view]
SUPFAM	SSF54695. BTB/POZ_fold. 1 hit.
PROSITE	PS50097. BTB. 1 hit. PS51490. KHA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	54793.
NextBio	57467.

Entry information

Entry name

KCTD9_HUMAN

Accession

Primary (citable) accession number: Q7L273
Secondary accession number(s): Q6NUM8, Q9NXV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.