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Q7L273

- KCTD9_HUMAN

UniProt

Q7L273 - KCTD9_HUMAN

Protein

BTB/POZ domain-containing protein KCTD9

Gene

KCTD9

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. protein homooligomerization Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    BTB/POZ domain-containing protein KCTD9
    Gene namesi
    Name:KCTD9
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:22401. KCTD9.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134869993.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389BTB/POZ domain-containing protein KCTD9PRO_0000191293Add
    BLAST

    Proteomic databases

    MaxQBiQ7L273.
    PaxDbiQ7L273.
    PRIDEiQ7L273.

    PTM databases

    PhosphoSiteiQ7L273.

    Expressioni

    Gene expression databases

    ArrayExpressiQ7L273.
    BgeeiQ7L273.
    CleanExiHS_KCTD9.
    GenevestigatoriQ7L273.

    Organism-specific databases

    HPAiHPA042468.

    Interactioni

    Protein-protein interaction databases

    BioGridi120153. 4 interactions.
    IntActiQ7L273. 2 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7L273.
    SMRiQ7L273. Positions 90-189, 217-377.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 8280KHAPROSITE-ProRule annotationAdd
    BLAST
    Domaini89 – 16173BTBPROSITE-ProRule annotationAdd
    BLAST
    Domaini273 – 29725Pentapeptide repeat 1Add
    BLAST
    Domaini303 – 34240Pentapeptide repeat 2Add
    BLAST
    Domaini343 – 37735Pentapeptide repeat 3Add
    BLAST

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation
    Contains 1 KHA domain.PROSITE-ProRule annotation
    Contains 3 pentapeptide repeat domains.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG1357.
    HOGENOMiHOG000010269.
    HOVERGENiHBG052243.
    InParanoidiQ7L273.
    OMAiNSQPAED.
    OrthoDBiEOG7FNC7P.
    PhylomeDBiQ7L273.
    TreeFamiTF313754.

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR001646. 5peptide_repeat.
    IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR021789. K_channel_plant.
    IPR003131. T1-type_BTB.
    [Graphical view]
    PfamiPF02214. BTB_2. 1 hit.
    PF11834. DUF3354. 1 hit.
    PF00805. Pentapeptide. 2 hits.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    PROSITEiPS50097. BTB. 1 hit.
    PS51490. KHA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7L273-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRRVTLFLNG SPKNGKVVAV YGTLSDLLSV ASSKLGIKAT SVYNGKGGLI    50
    DDIALIRDDD VLFVCEGEPF IDPQTDSKPP EGLLGFHTDW LTLNVGGRYF 100
    TTTRSTLVNK EPDSMLAHMF KDKGVWGNKQ DHRGAFLIDR SPEYFEPILN 150
    YLRHGQLIVN DGINLLGVLE EARFFGIDSL IEHLEVAIKN SQPPEDHSPI 200
    SRKEFVRFLL ATPTKSELRC QGLNFSGADL SRLDLRYINF KMANLSRCNL 250
    AHANLCCANL ERADLSGSVL DCANLQGVKM LCSNAEGASL KLCNFEDPSG 300
    LKANLEGANL KGVDMEGSQM TGINLRVATL KNAKLKNCNL RGATLAGTDL 350
    ENCDLSGCDL QEANLRGSNV KGAIFEEMLT PLHMSQSVR 389
    Length:389
    Mass (Da):42,567
    Last modified:July 5, 2004 - v1
    Checksum:i43D4AE36F3B9618F
    GO

    Sequence cautioni

    The sequence BAA90904.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti12 – 121P → R in AAH68518. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC021216 mRNA. Translation: AAH21216.2.
    BC068518 mRNA. Translation: AAH68518.1.
    AK000045 mRNA. Translation: BAA90904.1. Different initiation.
    CCDSiCCDS6048.1.
    RefSeqiNP_060104.2. NM_017634.3.
    UniGeneiHs.188763.
    Hs.72071.

    Genome annotation databases

    EnsembliENST00000221200; ENSP00000221200; ENSG00000104756.
    GeneIDi54793.
    KEGGihsa:54793.
    UCSCiuc003xeo.3. human.

    Polymorphism databases

    DMDMi50400921.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC021216 mRNA. Translation: AAH21216.2 .
    BC068518 mRNA. Translation: AAH68518.1 .
    AK000045 mRNA. Translation: BAA90904.1 . Different initiation.
    CCDSi CCDS6048.1.
    RefSeqi NP_060104.2. NM_017634.3.
    UniGenei Hs.188763.
    Hs.72071.

    3D structure databases

    ProteinModelPortali Q7L273.
    SMRi Q7L273. Positions 90-189, 217-377.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120153. 4 interactions.
    IntActi Q7L273. 2 interactions.

    PTM databases

    PhosphoSitei Q7L273.

    Polymorphism databases

    DMDMi 50400921.

    Proteomic databases

    MaxQBi Q7L273.
    PaxDbi Q7L273.
    PRIDEi Q7L273.

    Protocols and materials databases

    DNASUi 54793.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000221200 ; ENSP00000221200 ; ENSG00000104756 .
    GeneIDi 54793.
    KEGGi hsa:54793.
    UCSCi uc003xeo.3. human.

    Organism-specific databases

    CTDi 54793.
    GeneCardsi GC08M025341.
    HGNCi HGNC:22401. KCTD9.
    HPAi HPA042468.
    neXtProti NX_Q7L273.
    PharmGKBi PA134869993.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG1357.
    HOGENOMi HOG000010269.
    HOVERGENi HBG052243.
    InParanoidi Q7L273.
    OMAi NSQPAED.
    OrthoDBi EOG7FNC7P.
    PhylomeDBi Q7L273.
    TreeFami TF313754.

    Miscellaneous databases

    GenomeRNAii 54793.
    NextBioi 57467.
    PROi Q7L273.

    Gene expression databases

    ArrayExpressi Q7L273.
    Bgeei Q7L273.
    CleanExi HS_KCTD9.
    Genevestigatori Q7L273.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR001646. 5peptide_repeat.
    IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR021789. K_channel_plant.
    IPR003131. T1-type_BTB.
    [Graphical view ]
    Pfami PF02214. BTB_2. 1 hit.
    PF11834. DUF3354. 1 hit.
    PF00805. Pentapeptide. 2 hits.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    PROSITEi PS50097. BTB. 1 hit.
    PS51490. KHA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis and Uterus.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 151-389.
      Tissue: Colon.

    Entry informationi

    Entry nameiKCTD9_HUMAN
    AccessioniPrimary (citable) accession number: Q7L273
    Secondary accession number(s): Q6NUM8, Q9NXV4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 8
      Human chromosome 8: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3