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Q7L273 (KCTD9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
BTB/POZ domain-containing protein KCTD9
Gene names
Name:KCTD9
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 BTB (POZ) domain.

Contains 1 KHA domain.

Contains 3 pentapeptide repeat domains.

Sequence caution

The sequence BAA90904.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   DomainRepeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein homooligomerization

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389BTB/POZ domain-containing protein KCTD9
PRO_0000191293

Regions

Domain3 – 8280KHA
Domain89 – 16173BTB
Domain273 – 29725Pentapeptide repeat 1
Domain303 – 34240Pentapeptide repeat 2
Domain343 – 37735Pentapeptide repeat 3

Experimental info

Sequence conflict121P → R in AAH68518. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q7L273 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 43D4AE36F3B9618F

FASTA38942,567
        10         20         30         40         50         60 
MRRVTLFLNG SPKNGKVVAV YGTLSDLLSV ASSKLGIKAT SVYNGKGGLI DDIALIRDDD 

        70         80         90        100        110        120 
VLFVCEGEPF IDPQTDSKPP EGLLGFHTDW LTLNVGGRYF TTTRSTLVNK EPDSMLAHMF 

       130        140        150        160        170        180 
KDKGVWGNKQ DHRGAFLIDR SPEYFEPILN YLRHGQLIVN DGINLLGVLE EARFFGIDSL 

       190        200        210        220        230        240 
IEHLEVAIKN SQPPEDHSPI SRKEFVRFLL ATPTKSELRC QGLNFSGADL SRLDLRYINF 

       250        260        270        280        290        300 
KMANLSRCNL AHANLCCANL ERADLSGSVL DCANLQGVKM LCSNAEGASL KLCNFEDPSG 

       310        320        330        340        350        360 
LKANLEGANL KGVDMEGSQM TGINLRVATL KNAKLKNCNL RGATLAGTDL ENCDLSGCDL 

       370        380 
QEANLRGSNV KGAIFEEMLT PLHMSQSVR 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis and Uterus.
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 151-389.
Tissue: Colon.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC021216 mRNA. Translation: AAH21216.2.
BC068518 mRNA. Translation: AAH68518.1.
AK000045 mRNA. Translation: BAA90904.1. Different initiation.
CCDSCCDS6048.1.
RefSeqNP_060104.2. NM_017634.3.
UniGeneHs.188763.
Hs.72071.

3D structure databases

ProteinModelPortalQ7L273.
SMRQ7L273. Positions 90-189, 217-377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid120153. 4 interactions.
IntActQ7L273. 2 interactions.

PTM databases

PhosphoSiteQ7L273.

Polymorphism databases

DMDM50400921.

Proteomic databases

MaxQBQ7L273.
PaxDbQ7L273.
PRIDEQ7L273.

Protocols and materials databases

DNASU54793.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000221200; ENSP00000221200; ENSG00000104756.
GeneID54793.
KEGGhsa:54793.
UCSCuc003xeo.3. human.

Organism-specific databases

CTD54793.
GeneCardsGC08M025341.
HGNCHGNC:22401. KCTD9.
HPAHPA042468.
neXtProtNX_Q7L273.
PharmGKBPA134869993.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG1357.
HOGENOMHOG000010269.
HOVERGENHBG052243.
InParanoidQ7L273.
OMANSQPAED.
OrthoDBEOG7FNC7P.
PhylomeDBQ7L273.
TreeFamTF313754.

Gene expression databases

ArrayExpressQ7L273.
BgeeQ7L273.
CleanExHS_KCTD9.
GenevestigatorQ7L273.

Family and domain databases

Gene3D3.30.710.10. 1 hit.
InterProIPR001646. 5peptide_repeat.
IPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR021789. K_channel_plant.
IPR003131. T1-type_BTB.
[Graphical view]
PfamPF02214. BTB_2. 1 hit.
PF11834. DUF3354. 1 hit.
PF00805. Pentapeptide. 2 hits.
[Graphical view]
SMARTSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMSSF54695. SSF54695. 1 hit.
PROSITEPS50097. BTB. 1 hit.
PS51490. KHA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi54793.
NextBio57467.
PROQ7L273.

Entry information

Entry nameKCTD9_HUMAN
AccessionPrimary (citable) accession number: Q7L273
Secondary accession number(s): Q6NUM8, Q9NXV4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 8

Human chromosome 8: entries, gene names and cross-references to MIM