UniProtKB - Q7KZS0 (Q7KZS0_HUMAN)
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Protein
Submitted name:
Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
Gene
UBE2I
Organism
Homo sapiens (Human)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 93 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- SUMO transferase activity Source: InterPro
Keywordsi
Molecular function | TransferaseSAAS annotation |
Biological process | Ubl conjugation pathwayUniRule annotationSAAS annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)ImportedSubmitted name: Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast), isoform CRA_bImported |
Gene namesi | Name:UBE2IImported ORF Names:hCG_42687Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 7 – 137 | UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST | 131 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0424. Eukaryota. COG5078. LUCA. |
HOVERGENi | HBG063308. |
Family and domain databases
CDDi | cd00195. UBCc. 1 hit. |
Gene3Di | 3.10.110.10. 1 hit. |
InterProi | View protein in InterPro IPR027230. Ubc9. IPR000608. UBQ-conjugat_E2. IPR023313. UBQ-conjugating_AS. IPR016135. UBQ-conjugating_enzyme/RWD. |
PANTHERi | PTHR43927. PTHR43927. 1 hit. |
Pfami | View protein in Pfam PF00179. UQ_con. 1 hit. |
SUPFAMi | SSF54495. SSF54495. 1 hit. |
PROSITEi | View protein in PROSITE PS00183. UBIQUITIN_CONJUGAT_1. 1 hit. PS50127. UBIQUITIN_CONJUGAT_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q7KZS0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG
60 70 80 90 100
TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED
110 120 130 140 150
KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYWLV AALAPLVAAP
160 170 180
PRPSQGRLAG REWSTQAHPR DSQGPRLCGE GRGA
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 184 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT007010 mRNA. Translation: AAP35656.1. CH471112 Genomic DNA. Translation: EAW85674.1. |
UniGenei | Hs.302903. |
Similar proteinsi
Entry informationi
Entry namei | Q7KZS0_HUMAN | |
Accessioni | Q7KZS0Primary (citable) accession number: Q7KZS0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | March 28, 2018 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |