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Q7KYZ9 (Q7KYZ9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:alpha 1c-adrenoceptor subtype EMBL AAD14205.1
OrganismHomo sapiens (Human) EMBL AAD14205.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length143 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processactivation of phospholipase C activity

Inferred from electronic annotation. Source: Ensembl

adult heart development

Inferred from electronic annotation. Source: Ensembl

aging

Inferred from electronic annotation. Source: Ensembl

calcium ion transport into cytosol

Inferred from electronic annotation. Source: Ensembl

cell growth

Inferred from electronic annotation. Source: Ensembl

micturition

Inferred from electronic annotation. Source: Ensembl

negative regulation of Rho protein signal transduction

Inferred from electronic annotation. Source: Ensembl

negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure

Inferred from electronic annotation. Source: Ensembl

negative regulation of synaptic transmission, GABAergic

Inferred from electronic annotation. Source: Ensembl

norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure

Inferred from electronic annotation. Source: Ensembl

organ growth

Inferred from electronic annotation. Source: Ensembl

phospholipase C-activating G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

pilomotor reflex

Inferred from electronic annotation. Source: Ensembl

positive regulation of ERK1 and ERK2 cascade

Inferred from electronic annotation. Source: Ensembl

positive regulation of action potential

Inferred from electronic annotation. Source: Ensembl

positive regulation of cardiac muscle contraction

Inferred from electronic annotation. Source: Ensembl

positive regulation of heart rate by epinephrine-norepinephrine

Inferred from electronic annotation. Source: Ensembl

positive regulation of protein kinase C signaling

Inferred from electronic annotation. Source: Ensembl

positive regulation of smooth muscle contraction

Inferred from electronic annotation. Source: Ensembl

positive regulation of systemic arterial blood pressure

Inferred from electronic annotation. Source: Ensembl

positive regulation of the force of heart contraction by epinephrine-norepinephrine

Inferred from electronic annotation. Source: Ensembl

positive regulation of vasoconstriction

Inferred from electronic annotation. Source: Ensembl

response to drug

Inferred from electronic annotation. Source: Ensembl

response to hormone

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentT-tubule

Inferred from electronic annotation. Source: Ensembl

Z disc

Inferred from electronic annotation. Source: Ensembl

integral component of membrane

Inferred from electronic annotation. Source: InterPro

   Molecular_functionalpha1-adrenergic receptor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1431 EMBL AAD14205.1

Sequences

Sequence LengthMass (Da)Tools
Q7KYZ9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: C3284E15C08E3AEE

FASTA14316,177
        10         20         30         40         50         60 
VMYCRVYVVA KRESRGLKSG LKTDKSDSEQ VTLRIHRKNA PAGGSGMASA KTKTHFSVRL 

        70         80         90        100        110        120 
LKFSREKKAA KTLGIVVGCF VLCWLPFFLV MPIGSFFPDF KPSETVFKIV FWLGYLNSCI 

       130        140 
NPIIYPCSSQ EFKKAFQNVL RIQ 

« Hide

References

[1]"Identification of the alpha 1c-adrenoceptor in rabbit arteries and the human saphenous vein using the polymerase chain reaction."
Diehl N.L., Shreeve S.M.
Eur. J. Pharmacol. 268:393-398(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S76001 mRNA. Translation: AAD14205.1.
UniGeneHs.709175.

3D structure databases

ProteinModelPortalQ7KYZ9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

H-InvDBHIX0034243.

Phylogenomic databases

HOGENOMHOG000239244.

Gene expression databases

ArrayExpressQ7KYZ9.
BgeeQ7KYZ9.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR001004. ADRA1A_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00557. ADRENRGCA1AR.
PR00237. GPCRRHODOPSN.
PROSITEPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7KYZ9_HUMAN
AccessionPrimary (citable) accession number: Q7KYZ9
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.