Q7KYZ9 (Q7KYZ9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha 1c-adrenoceptor subtype protein EMBL AAD14205.1

Gene names

Name:

alpha 1c-adrenoceptor subtype EMBL AAD14205.1

Organism

Homo sapiens (Human) EMBL AAD14205.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	143 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	activation of phospholipase C activity Inferred from electronic annotation. Source: Compara adult heart development Inferred from electronic annotation. Source: Compara aging Inferred from electronic annotation. Source: Compara calcium ion transport into cytosol Inferred from electronic annotation. Source: Compara cell growth Inferred from electronic annotation. Source: Compara micturition Inferred from electronic annotation. Source: Compara negative regulation of Rho protein signal transduction Inferred from electronic annotation. Source: Compara negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure Inferred from electronic annotation. Source: Compara negative regulation of synaptic transmission, GABAergic Inferred from electronic annotation. Source: Compara norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure Inferred from electronic annotation. Source: Compara organ growth Inferred from electronic annotation. Source: Compara phospholipase C-activating G-protein coupled receptor signaling pathway Inferred from electronic annotation. Source: Compara pilomotor reflex Inferred from electronic annotation. Source: Compara positive regulation of ERK1 and ERK2 cascade Inferred from electronic annotation. Source: Compara positive regulation of action potential Inferred from electronic annotation. Source: Compara positive regulation of cardiac muscle contraction Inferred from electronic annotation. Source: Compara positive regulation of heart rate by epinephrine-norepinephrine Inferred from electronic annotation. Source: Compara positive regulation of protein kinase C signaling cascade Inferred from electronic annotation. Source: Compara positive regulation of smooth muscle contraction Inferred from electronic annotation. Source: Compara positive regulation of systemic arterial blood pressure Inferred from electronic annotation. Source: Compara positive regulation of the force of heart contraction by epinephrine-norepinephrine Inferred from electronic annotation. Source: Compara positive regulation of vasoconstriction Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to hormone stimulus Inferred from electronic annotation. Source: Compara response to stress Inferred from electronic annotation. Source: Compara
Cellular_component	T-tubule Inferred from electronic annotation. Source: Compara Z disc Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	alpha1-adrenergic receptor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	143	1	EMBL AAD14205.1

Sequences

	Sequence		Length	Mass (Da)
	Q7KYZ9 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C3284E15C08E3AEE	FASTA	143	16,177
	10 20 30 40 50 60 VMYCRVYVVA KRESRGLKSG LKTDKSDSEQ VTLRIHRKNA PAGGSGMASA KTKTHFSVRL 70 80 90 100 110 120 LKFSREKKAA KTLGIVVGCF VLCWLPFFLV MPIGSFFPDF KPSETVFKIV FWLGYLNSCI 130 140 NPIIYPCSSQ EFKKAFQNVL RIQ

References

[1]	"Identification of the alpha 1c-adrenoceptor in rabbit arteries and the human saphenous vein using the polymerase chain reaction." Diehl N.L., Shreeve S.M. Eur. J. Pharmacol. 268:393-398(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S76001 mRNA. Translation: AAD14205.1.
IPI	IPI00983651.
UniGene	Hs.709175.
3D structure databases
ProteinModelPortal	Q7KYZ9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7KYZ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
H-InvDB	HIX0034243.
Phylogenomic databases
HOGENOM	HOG000239244.
Gene expression databases
ArrayExpress	Q7KYZ9.
Bgee	Q7KYZ9.
Family and domain databases
InterPro	IPR001004. Adrene_rcpt_A1Cs. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00557. ADRENRGCA1AR. PR00237. GPCRRHODOPSN.
PROSITE	PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7KYZ9_HUMAN

Accession

Primary (citable) accession number: Q7KYZ9

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.