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Protein
Submitted name:

Alpha 1c-adrenoceptor subtype protein

Gene

alpha 1c-adrenoceptor subtype

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha 1c-adrenoceptor subtype proteinImported
Gene namesi
Name:alpha 1c-adrenoceptor subtypeImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei72 – 97HelicalSequence analysisAdd BLAST26
Transmembranei109 – 127HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ7KYZ9.

Expressioni

Gene expression databases

BgeeiENSG00000120907.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369960.

Structurei

3D structure databases

ProteinModelPortaliQ7KYZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 125G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST125

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000239244.

Family and domain databases

InterProiIPR001004. ADRA1A_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00557. ADRENRGCA1AR.
PR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q7KYZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VMYCRVYVVA KRESRGLKSG LKTDKSDSEQ VTLRIHRKNA PAGGSGMASA
60 70 80 90 100
KTKTHFSVRL LKFSREKKAA KTLGIVVGCF VLCWLPFFLV MPIGSFFPDF
110 120 130 140
KPSETVFKIV FWLGYLNSCI NPIIYPCSSQ EFKKAFQNVL RIQ
Length:143
Mass (Da):16,177
Last modified:July 5, 2004 - v1
Checksum:iC3284E15C08E3AEE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei143Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S76001 mRNA. Translation: AAD14205.1.
UniGeneiHs.52931.
Hs.709175.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S76001 mRNA. Translation: AAD14205.1.
UniGeneiHs.52931.
Hs.709175.

3D structure databases

ProteinModelPortaliQ7KYZ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369960.

Proteomic databases

PaxDbiQ7KYZ9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

H-InvDBHIX0034243.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOGENOMiHOG000239244.

Gene expression databases

BgeeiENSG00000120907.

Family and domain databases

InterProiIPR001004. ADRA1A_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00557. ADRENRGCA1AR.
PR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7KYZ9_HUMAN
AccessioniPrimary (citable) accession number: Q7KYZ9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.