Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q7KYR7

- BT2A1_HUMAN

UniProt

Q7KYR7 - BT2A1_HUMAN

Protein

Butyrophilin subfamily 2 member A1

Gene

BTN2A1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 3 (25 Nov 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Biological processi

    1. lipid metabolic process Source: ProtInc

    Protein family/group databases

    MEROPSiI43.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Butyrophilin subfamily 2 member A1
    Gene namesi
    Name:BTN2A1
    Synonyms:BT2.1, BTF1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 6

    Organism-specific databases

    HGNCiHGNC:1136. BTN2A1.

    Subcellular locationi

    Membrane By similarity; Single-pass type I membrane protein By similarity

    GO - Cellular componenti

    1. extracellular vesicular exosome Source: UniProt
    2. integral component of plasma membrane Source: ProtInc

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA25456.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Sequence AnalysisAdd
    BLAST
    Chaini29 – 527499Butyrophilin subfamily 2 member A1PRO_0000014529Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi46 – 461N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi51 ↔ 125PROSITE-ProRule annotation
    Glycosylationi114 – 1141N-linked (GlcNAc...)1 Publication
    Glycosylationi120 – 1201N-linked (GlcNAc...)1 Publication

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    MaxQBiQ7KYR7.
    PaxDbiQ7KYR7.
    PRIDEiQ7KYR7.

    PTM databases

    PhosphoSiteiQ7KYR7.

    Expressioni

    Tissue specificityi

    Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.1 Publication

    Gene expression databases

    ArrayExpressiQ7KYR7.
    BgeeiQ7KYR7.
    CleanExiHS_BTN2A1.
    GenevestigatoriQ7KYR7.

    Organism-specific databases

    HPAiHPA019208.

    Interactioni

    Protein-protein interaction databases

    BioGridi116295. 1 interaction.
    IntActiQ7KYR7. 2 interactions.
    STRINGi9606.ENSP00000312158.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7KYR7.
    SMRiQ7KYR7. Positions 28-237, 287-501.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini29 – 248220ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini270 – 527258CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei249 – 26921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini29 – 141113Ig-like V-typeAdd
    BLAST
    Domaini310 – 506197B30.2/SPRYPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 B30.2/SPRY domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG253704.
    HOGENOMiHOG000230860.
    HOVERGENiHBG050747.
    InParanoidiQ7KYR7.
    KOiK06712.
    OMAiEMRGHED.
    PhylomeDBiQ7KYR7.
    TreeFamiTF331083.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    InterProiIPR001870. B30.2/SPRY.
    IPR003879. Butyrophylin.
    IPR013162. CD80_C2-set.
    IPR008985. ConA-like_lec_gl_sf.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    IPR006574. PRY.
    IPR018355. SPla/RYanodine_receptor_subgr.
    IPR003877. SPRY_rcpt.
    [Graphical view]
    PfamiPF08205. C2-set_2. 1 hit.
    PF13765. PRY. 1 hit.
    PF00622. SPRY. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view]
    PRINTSiPR01407. BUTYPHLNCDUF.
    SMARTiSM00409. IG. 1 hit.
    SM00589. PRY. 1 hit.
    SM00449. SPRY. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS50188. B302_SPRY. 1 hit.
    PS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q7KYR7-2) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MESAAALHFS RPASLLLLLL SLCALVSAQF IVVGPTDPIL ATVGENTTLR    50
    CHLSPEKNAE DMEVRWFRSQ FSPAVFVYKG GRERTEEQME EYRGRTTFVS 100
    KDISRGSVAL VIHNITAQEN GTYRCYFQEG RSYDEAILHL VVAGLGSKPL 150
    ISMRGHEDGG IRLECISRGW YPKPLTVWRD PYGGVAPALK EVSMPDADGL 200
    FMVTTAVIIR DKSVRNMSCS INNTLLGQKK ESVIFIPESF MPSVSPCAVA 250
    LPIIVVILMI PIAVCIYWIN KLQKEKKILS GEKEFERETR EIALKELEKE 300
    RVQKEEELQV KEKLQEELRW RRTFLHAVDV VLDPDTAHPD LFLSEDRRSV 350
    RRCPFRHLGE SVPDNPERFD SQPCVLGRES FASGKHYWEV EVENVIEWTV 400
    GVCRDSVERK GEVLLIPQNG FWTLEMHKGQ YRAVSSPDRI LPLKESLCRV 450
    GVFLDYEAGD VSFYNMRDRS HIYTCPRSAF SVPVRPFFRL GCEDSPIFIC 500
    PALTGANGVT VPEEGLTLHR VGTHQSL 527
    Length:527
    Mass (Da):59,633
    Last modified:November 25, 2008 - v3
    Checksum:i0EB0731062E02F6C
    GO
    Isoform 2 (identifier: Q7KYR7-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         247-262: CAVALPIIVVILMIPI → L
         482-527: VPVRPFFRLG...LHRVGTHQSL → GPDTSQSGDP...SFLLLTRLCF

    Show »
    Length:528
    Mass (Da):60,004
    Checksum:i22EAF9F31FA2343B
    GO
    Isoform 3 (identifier: Q7KYR7-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-152: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:375
    Mass (Da):42,770
    Checksum:iFB6932C0E209A02B
    GO
    Isoform 4 (identifier: Q7KYR7-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         328-334: VDVVLDP → ELQFFSN
         335-527: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:334
    Mass (Da):37,853
    Checksum:i3BF0FE990D1F8095
    GO
    Isoform 5 (identifier: Q7KYR7-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-61: Missing.

    Show »
    Length:466
    Mass (Da):53,204
    Checksum:i854139B0C8D0E3F4
    GO
    Isoform 6 (identifier: Q7KYR7-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         328-330: VDV → GPV
         331-527: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:330
    Mass (Da):37,240
    Checksum:iC91FC3F56606AF92
    GO

    Sequence cautioni

    The sequence BAD93014.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence CAB71221.2 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti29 – 291Q → H in AAC02650. (PubMed:9382921)Curated
    Sequence conflicti29 – 291Q → H in AAC02653. (PubMed:9382921)Curated
    Sequence conflicti119 – 1191E → G in AAC02650. (PubMed:9382921)Curated
    Sequence conflicti119 – 1191E → G in AAC02653. (PubMed:9382921)Curated
    Sequence conflicti144 – 1441G → ER in AAC02650. (PubMed:9382921)Curated
    Sequence conflicti144 – 1441G → ER in AAC02653. (PubMed:9382921)Curated
    Sequence conflicti208 – 2081I → V in CAD97989. (PubMed:17974005)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti124 – 1241R → C.
    Corresponds to variant rs3734539 [ dbSNP | Ensembl ].
    VAR_049825
    Natural varianti178 – 1781W → C.
    Corresponds to variant rs13195402 [ dbSNP | Ensembl ].
    VAR_061303
    Natural varianti178 – 1781W → L.
    Corresponds to variant rs13195401 [ dbSNP | Ensembl ].
    VAR_061304
    Natural varianti207 – 2071V → M.
    Corresponds to variant rs13195509 [ dbSNP | Ensembl ].
    VAR_049826
    Natural varianti378 – 3781R → Q.
    Corresponds to variant rs3734542 [ dbSNP | Ensembl ].
    VAR_049827
    Natural varianti451 – 4511G → A.
    Corresponds to variant rs3734543 [ dbSNP | Ensembl ].
    VAR_049828

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 152152Missing in isoform 3. 1 PublicationVSP_012708Add
    BLAST
    Alternative sequencei1 – 6161Missing in isoform 5. 1 PublicationVSP_044249Add
    BLAST
    Alternative sequencei247 – 26216CAVAL…LMIPI → L in isoform 2. 1 PublicationVSP_035843Add
    BLAST
    Alternative sequencei328 – 3347VDVVLDP → ELQFFSN in isoform 4. 1 PublicationVSP_043165
    Alternative sequencei328 – 3303VDV → GPV in isoform 6. 1 PublicationVSP_045005
    Alternative sequencei331 – 527197Missing in isoform 6. 1 PublicationVSP_045006Add
    BLAST
    Alternative sequencei335 – 527193Missing in isoform 4. 1 PublicationVSP_043166Add
    BLAST
    Alternative sequencei482 – 52746VPVRP…THQSL → GPDTSQSGDPPEPIESIPWS HSHVDKPWSFQQPPHNTHLP AASFTPTTDLSPSFLLLTRL CF in isoform 2. 1 PublicationVSP_035844Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U90142 mRNA. Translation: AAC02650.1.
    U97496, U97495 Genomic DNA. Translation: AAC02653.1.
    U97497 Genomic DNA. Translation: AAC02654.1.
    U90543 mRNA. Translation: AAB53421.1.
    BX538050 mRNA. Translation: CAD97989.1.
    AK297098 mRNA. Translation: BAG59611.1.
    AB209777 mRNA. Translation: BAD93014.1. Different initiation.
    AL050330, AL121936 Genomic DNA. Translation: CAB71221.2. Sequence problems.
    BC016661 mRNA. Translation: AAH16661.1.
    CCDSiCCDS4613.1. [Q7KYR7-2]
    CCDS47390.1. [Q7KYR7-4]
    CCDS56404.1. [Q7KYR7-6]
    CCDS56405.1. [Q7KYR7-5]
    RefSeqiNP_001184162.1. NM_001197233.2. [Q7KYR7-5]
    NP_001184163.1. NM_001197234.2. [Q7KYR7-6]
    NP_008980.1. NM_007049.4. [Q7KYR7-2]
    NP_510961.1. NM_078476.3. [Q7KYR7-4]
    UniGeneiHs.159028.

    Genome annotation databases

    EnsembliENST00000312541; ENSP00000312158; ENSG00000112763. [Q7KYR7-2]
    ENST00000429381; ENSP00000416945; ENSG00000112763. [Q7KYR7-4]
    ENST00000469185; ENSP00000419043; ENSG00000112763. [Q7KYR7-6]
    ENST00000541522; ENSP00000443909; ENSG00000112763. [Q7KYR7-5]
    GeneIDi11120.
    KEGGihsa:11120.
    UCSCiuc003nib.2. human. [Q7KYR7-2]
    uc003nic.2. human. [Q7KYR7-4]

    Polymorphism databases

    DMDMi215274180.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U90142 mRNA. Translation: AAC02650.1 .
    U97496 , U97495 Genomic DNA. Translation: AAC02653.1 .
    U97497 Genomic DNA. Translation: AAC02654.1 .
    U90543 mRNA. Translation: AAB53421.1 .
    BX538050 mRNA. Translation: CAD97989.1 .
    AK297098 mRNA. Translation: BAG59611.1 .
    AB209777 mRNA. Translation: BAD93014.1 . Different initiation.
    AL050330 , AL121936 Genomic DNA. Translation: CAB71221.2 . Sequence problems.
    BC016661 mRNA. Translation: AAH16661.1 .
    CCDSi CCDS4613.1. [Q7KYR7-2 ]
    CCDS47390.1. [Q7KYR7-4 ]
    CCDS56404.1. [Q7KYR7-6 ]
    CCDS56405.1. [Q7KYR7-5 ]
    RefSeqi NP_001184162.1. NM_001197233.2. [Q7KYR7-5 ]
    NP_001184163.1. NM_001197234.2. [Q7KYR7-6 ]
    NP_008980.1. NM_007049.4. [Q7KYR7-2 ]
    NP_510961.1. NM_078476.3. [Q7KYR7-4 ]
    UniGenei Hs.159028.

    3D structure databases

    ProteinModelPortali Q7KYR7.
    SMRi Q7KYR7. Positions 28-237, 287-501.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116295. 1 interaction.
    IntActi Q7KYR7. 2 interactions.
    STRINGi 9606.ENSP00000312158.

    Protein family/group databases

    MEROPSi I43.001.

    PTM databases

    PhosphoSitei Q7KYR7.

    Polymorphism databases

    DMDMi 215274180.

    Proteomic databases

    MaxQBi Q7KYR7.
    PaxDbi Q7KYR7.
    PRIDEi Q7KYR7.

    Protocols and materials databases

    DNASUi 11120.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000312541 ; ENSP00000312158 ; ENSG00000112763 . [Q7KYR7-2 ]
    ENST00000429381 ; ENSP00000416945 ; ENSG00000112763 . [Q7KYR7-4 ]
    ENST00000469185 ; ENSP00000419043 ; ENSG00000112763 . [Q7KYR7-6 ]
    ENST00000541522 ; ENSP00000443909 ; ENSG00000112763 . [Q7KYR7-5 ]
    GeneIDi 11120.
    KEGGi hsa:11120.
    UCSCi uc003nib.2. human. [Q7KYR7-2 ]
    uc003nic.2. human. [Q7KYR7-4 ]

    Organism-specific databases

    CTDi 11120.
    GeneCardsi GC06P026458.
    H-InvDB HIX0005650.
    HGNCi HGNC:1136. BTN2A1.
    HPAi HPA019208.
    MIMi 613590. gene.
    neXtProti NX_Q7KYR7.
    PharmGKBi PA25456.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG253704.
    HOGENOMi HOG000230860.
    HOVERGENi HBG050747.
    InParanoidi Q7KYR7.
    KOi K06712.
    OMAi EMRGHED.
    PhylomeDBi Q7KYR7.
    TreeFami TF331083.

    Miscellaneous databases

    ChiTaRSi BTN2A1. human.
    GenomeRNAii 11120.
    NextBioi 42264.
    PROi Q7KYR7.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q7KYR7.
    Bgeei Q7KYR7.
    CleanExi HS_BTN2A1.
    Genevestigatori Q7KYR7.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    InterProi IPR001870. B30.2/SPRY.
    IPR003879. Butyrophylin.
    IPR013162. CD80_C2-set.
    IPR008985. ConA-like_lec_gl_sf.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    IPR006574. PRY.
    IPR018355. SPla/RYanodine_receptor_subgr.
    IPR003877. SPRY_rcpt.
    [Graphical view ]
    Pfami PF08205. C2-set_2. 1 hit.
    PF13765. PRY. 1 hit.
    PF00622. SPRY. 1 hit.
    PF07686. V-set. 1 hit.
    [Graphical view ]
    PRINTSi PR01407. BUTYPHLNCDUF.
    SMARTi SM00409. IG. 1 hit.
    SM00589. PRY. 1 hit.
    SM00449. SPRY. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS50188. B302_SPRY. 1 hit.
    PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex."
      Tazi-Ahnini R., Henry J., Offer C., Bouissou-Bouchouata C., Mather I.H., Pontarotti P.
      Immunogenetics 47:55-63(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 2).
    2. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Colon endothelium.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5).
      Tissue: Placenta.
    5. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
      Tissue: Brain.
    6. "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
      , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
      Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
      Tissue: Lymph.
    8. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
      Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-114 AND ASN-120.
      Tissue: Leukemic T-cell.

    Entry informationi

    Entry nameiBT2A1_HUMAN
    AccessioniPrimary (citable) accession number: Q7KYR7
    Secondary accession number(s): B4DLP9
    , E9PGR4, O00475, P78408, Q59EN4, Q7KYQ7, Q7Z386, Q96AV7, Q9NU62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 2005
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 107 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 6
      Human chromosome 6: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3