Unreviewed, UniProtKB/TrEMBL Q7KUA4 (Q7KUA4_DROME)

Names and origin

Protein names

Submitted name:
    Smt3 activating enzyme 2 EMBL AAF50484.2
Submitted name:
    LD22577p EMBL AAM29366.1

Gene names

Name:	Uba2 EMBL AAF50484.2 FlyBase FBgn0029113
ORF Names:	Dmel_CG7528 EMBL AAF50484.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	700 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	positive regulation of NF-kappaB transcription factor activity Inferred from direct assay. Source: FlyBase protein modification process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase nucleus Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: FlyBase small protein activating enzyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7KUA4-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F753AD03375FA9CE	FASTA	700	77,611
	10 20 30 40 50 60 MAAAINGVFP PTLQELVKKS KVLVVGAGGI GCEVLKNLVL SGFTDIEIID LDTIDLSNLN 70 80 90 100 110 120 RQFLFHREHV GKSKARVARE SALSFNPDAK ITAYHDSVTS TDYGVNFFKK FDLVLSALDN 130 140 150 160 170 180 RAARNHVNRM CLNADVPLIE SGTAGYNGQV ELIKRGLTQC YECTPKDKQR SFPGCTIRNT 190 200 210 220 230 240 PSEPIHCIVW AKHLFNQLFG ESLEDEDISP DAADPDAKEK DGGDGNGEPK GDGKEKGEES 250 260 270 280 290 300 KEEKEAKEDT ANGNIMRINT RQWAKDCNYD AGKLFNKFFN EDITYLLRMS NLWKTRKAPV 310 320 330 340 350 360 PVQWDTLLPE GSSGDQKDVA KQHHKVWSIE ECAQVFANSL KELSANFLKL EGDDTLAWDK 370 380 390 400 410 420 DDQPAMDFVA ACANVRSHIF DIERKSRFEI KSMAGNIIPA IATTNAITAG ISVMRAFKVL 430 440 450 460 470 480 EAKWEQCKAV YARLRPNARN HFLVPDASLP GPNPNCHVCA SDPAITLKID TKRMRIKELR 490 500 510 520 530 540 DEVLVKTLNM LNPDVTVQSN GSILISSEEG ETECNDGKLL SELNIVDGVI LKCDDFFQNY 550 560 570 580 590 600 ELSIIISHFD AERDENLFEV VADASQLKPK DEDQKEAVKD KEDEPKSAKK RSTNGEGDSK 610 620 630 640 650 660 DDGPSTSKRS RPNEVVEEDD DDCLVIEEDE DQADVVVVAT DKLSVQSPPK SGSKRKPCEV 670 680 690 700 IEDEDITEIL ESSDDEPAGP TKCKRSRLDD SNPVAVISID

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM29366.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014296 Genomic DNA. Translation: AAF50484.2. AY113361 mRNA. Translation: AAM29366.1.
RefSeq	NP_524756.2.
UniGene	Dm.6538
3D structure databases
HSSP	HSSP built from PDB template 1JWA based on UniProtKB P12282.
ModBase	Search...
Proteomic databases
PRIDE	Q7KUA4.
Genome annotation databases
Ensembl	FBgn0029113. Drosophila melanogaster. [Contig view]
GeneID	44496.
KEGG	dme:Dmel_CG7528.
NMPDR	fig|7227.3.peg.8792.
Organism-specific databases
FlyBase	FBgn0029113. Uba2.
Phylogenomic databases
OMA	Q7KUA4. WEPMEAE.
Gene expression databases
ArrayExpress	Q7KUA4.
Family and domain databases
InterPro	IPR000594. ThiF_NAD_FAD_bd. IPR000127. UBact_repeat. IPR019572. Ubiquitin-activating_enzyme. IPR018074. UBQ-activ_enz_E1_AS. [Graphical view]
Pfam	PF00899. ThiF. 1 hit. PF10585. UBA_e1_thiolCys. 1 hit. PF02134. UBACT. 1 hit. [Graphical view]
PROSITE	PS00865. UBIQUITIN_ACTIVAT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	837320.

Entry information

Entry name

Q7KUA4_DROME

Accession

Primary (citable) accession number: Q7KUA4

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)