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Q7KSQ2 (Q7KSQ2_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
C-terminal Src kinase, isoform F EMBL AAO41544.1
EC=2.7.10.- EMBL AAO41544.1
EC=2.7.10.2 EMBL AAO41544.1
Submitted name:
C-terminal Src kinase, isoform I EMBL AAN13519.1
EC=2.7.10.- EMBL AAN13519.1
EC=2.7.10.2 EMBL AAN13519.1
Submitted name:
C-terminal Src kinase, isoform J EMBL AAN13520.1
EC=2.7.10.- EMBL AAN13520.1
EC=2.7.10.2 EMBL AAN13520.1
Submitted name:
C-terminal Src kinase, isoform K EMBL AAN13521.1
EC=2.7.10.- EMBL AAN13521.1
EC=2.7.10.2 EMBL AAN13521.1
Gene names
Name:Csk FlyBase FBgn0037925 FlyBase FBgn0086688 FlyBase FBgn0259217 FlyBase FBgn0262081 FlyBase FBgn0086903
ORF Names:Dmel_CG42317 EMBL AAN13519.1
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length723 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SAAS SAAS020635

Sequence similarities

Contains 1 protein kinase domain. SAAS SAAS020635

Sequences

Sequence LengthMass (Da)Tools
Q7KSQ2 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 9BC596A6A45DAF6B

FASTA72378,047
        10         20         30         40         50         60 
MNSHATATQN GQTTVVGHHR GFSQPSVTVA AAAATGSTAG DPWFLQTTGH QMPPTAPLRH 

        70         80         90        100        110        120 
NKRPAPQPNA VLGAGSSGTA PGSAVGAVLL HQQQLSQSQP HIVPPSIPPH HHHHRENNVH 

       130        140        150        160        170        180 
PIQAGAAAAL HLSSHALNSH NLISSASNHS PKSPSQTQQQ QQTTNQQQQQ QQQQASHSIL 

       190        200        210        220        230        240 
STFAPAPTVA AVQPAGSQSV AGTAAAVAAV AQQQQQQHLQ LLANCPPGGA GLMSSSLNAA 

       250        260        270        280        290        300 
QMGMHGAERA LPPKSLALSG SQHGSNMLLH TAPQPPQASQ PAAVVGVSGS GSAGMSTSLH 

       310        320        330        340        350        360 
SFDINGVTAG SGVNASSAWS SGSTTAMNHA SLSPTALAPQ QGRSRCEVKL NAMPWFHGSI 

       370        380        390        400        410        420 
TRDEAEHLLQ PREDGLFLVR ESTNFPGDYT LCVCFQSKVE HYRVKYLENK LTIDDEEYFE 

       430        440        450        460        470        480 
NLGQLVAHYE ADADGLCTQL IKCLPKLGKQ EFCINSKDFV DKGWVIPEAE LQLRESIGKG 

       490        500        510        520        530        540 
EFGDVMLGIL RNEKVAVKML KDEGAVQKFL AEASVMTTLE HDNLVKFIGL VFTSKHLYLV 

       550        560        570        580        590        600 
TEYMSKGSLV DYLRSRGRQH ITKKDQIIFA YDTASGMEYL EAKKVVHRDL AARNVLISED 

       610        620        630        640        650        660 
CVAKVSDFGL AREECYNLDV GKLPIKWTAP EALKNGRFSN KSDMWSFGIL LWEIYSFGRV 

       670        680        690        700        710        720 
PYPRIPLADV VKHVEVGYKM EAPEGCPPEI YEMMRQAWDL NPAKRPTFAE LKVKLQLLNN 


ATA

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014297 Genomic DNA. Translation: AAN13519.1.
AE014297 Genomic DNA. Translation: AAN13520.1.
AE014297 Genomic DNA. Translation: AAN13521.1.
AE014297 Genomic DNA. Translation: AAO41544.1.
RefSeqNP_731607.1. NM_169414.1.
NP_731608.1. NM_169415.2.
NP_731609.1. NM_169416.2.
NP_788638.1. NM_176461.1.
UniGeneDm.37763.

3D structure databases

HSSPHSSP built from PDB template 1K9A based on UniProtKB P32577.
ProteinModelPortalQ7KSQ2.
SMRQ7KSQ2. Positions 307-721.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7KSQ2.

Proteomic databases

PRIDEQ7KSQ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0299728; FBpp0289006; FBgn0262081.
FBtr0300547; FBpp0289774; FBgn0262081.
FBtr0300548; FBpp0289775; FBgn0262081.
FBtr0300549; FBpp0289776; FBgn0262081.
GeneID41398.
KEGGdme:Dmel_CG42317.

Organism-specific databases

CTD1445.
FlyBaseFBgn0262081. Csk.

Phylogenomic databases

GeneTreeEMGT00050000002730.
InParanoidQ7KSQ2.
OrthoDBEOG4D7WMW.

Gene expression databases

ArrayExpressQ7KSQ2.
BgeeQ7KSQ2.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase.
IPR000980. SH2.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
[Graphical view]
Gene3DG3DSA:3.30.505.10. SH2. 1 hit.
KOK05728.
PfamPF07714. Pkinase_Tyr. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
PRINTSPR00401. SH2DOMAIN.
PR00109. TYRKINASE.
SMARTSM00252. SH2. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS50001. SH2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio823661.

Entry information

Entry nameQ7KSQ2_DROME
AccessionPrimary (citable) accession number: Q7KSQ2
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info