Q7KS72 (Q7KS72_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
C15 EMBL AAF55898.2

Submitted name:
FI01111p EMBL ABF17894.1

Gene names

Name:	C15 FlyBase FBgn0004863 EMBL AAF55898.2
ORF Names:	Dmel_CG7937 EMBL AAF55898.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity RuleBase RU000682.

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682
Domain	Homeobox RuleBase RU000682
Ligand	DNA-binding RuleBase RU000682
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	chaeta development Inferred from mutant phenotype. Source: FlyBase elongation of arista core Inferred from mutant phenotype. Source: FlyBase imaginal disc-derived leg morphogenesis Inferred from mutant phenotype. Source: FlyBase mesodermal cell fate specification Non-traceable author statement. Source: FlyBase negative regulation of transcription, DNA-dependent Inferred from mutant phenotype. Source: FlyBase positive regulation of Notch signaling pathway Inferred from expression pattern. Source: FlyBase positive regulation of transcription, DNA-dependent Inferred from mutant phenotype. Source: FlyBase
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell protein complex Inferred from physical interaction. Source: FlyBase
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7KS72 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 8C2FC4A98B7E46BD	FASTA	339	37,367
	10 20 30 40 50 60 MSSHEEDDHE HENEHGEEVE EQEIHVDVDS DSRMSCGSGS DVDMDGGSCY DESETPLSES 70 80 90 100 110 120 LQSEQTRSSS SENLPFSISR LLSKPFETSH HHHNNNNHLL SSSPGSSSNN NNSGEKGEEK 130 140 150 160 170 180 ELLQQEDHDL AYKLATSIAN STYGSAAALY SYPHLYPSAA GGHVLRVPPQ RTPLTWALPP 190 200 210 220 230 240 LHHAALAHQA VKDRLAAAFP IARRIGHPYQ NRTPPKRKKP RTSFTRIQVA ELEKRFHKQK 250 260 270 280 290 300 YLASAERAAL ARGLKMTDAQ VKTWFQNRRT KWRRQTAEER EAERQAANRL MLSLQAEAIS 310 320 330 KGFAPPSAPL GSQGGVNGAP LAALHGLQPW AEASHAAGC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Carlson J., Frise E., Kapadia B., Park S., Wan K., Yu C., Celniker S. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF55898.2. BT025203 mRNA. Translation: ABF17894.1.
RefSeq	NP_476873.2. NM_057525.2.
UniGene	Dm.2657.
3D structure databases
HSSP	HSSP built from PDB template 1B72 based on UniProtKB P14653.
ProteinModelPortal	Q7KS72.
SMR	Q7KS72. Positions 202-279.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7KS72.
Proteomic databases
PRIDE	Q7KS72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0084111; FBpp0083510; FBgn0004863.
GeneID	42544.
KEGG	dme:Dmel_CG7937.
NMPDR	fig|7227.3.peg.13932.
UCSC	CG7937-RA. d. melanogaster.
Organism-specific databases
CTD	42544.
FlyBase	FBgn0004863. C15.
Phylogenomic databases
InParanoid	Q7KS72.
OMA	SHEEDEH.
PhylomeDB	Q7KS72.
Gene expression databases
ArrayExpress	Q7KS72.
Bgee	Q7KS72.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
KO	K15607.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	829343.

Entry information

Entry name

Q7KS72_DROME

Accession

Primary (citable) accession number: Q7KS72

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)