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Protein

40S ribosomal protein S19b

Gene

RpS19b

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • ribosomal small subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S19b
Gene namesi
Name:RpS19b
Synonyms:RpS19
ORF Names:CG5338
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0039129. RpS19b.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001538252 – 15540S ribosomal protein S19bAdd BLAST154

Proteomic databases

PaxDbiQ7KS38.
PRIDEiQ7KS38.

Expressioni

Gene expression databases

BgeeiFBgn0039129.
ExpressionAtlasiQ7KS38. differential.
GenevisibleiQ7KS38. DM.

Interactioni

Protein-protein interaction databases

BioGridi67766. 9 interactors.
IntActiQ7KS38. 6 interactors.
STRINGi7227.FBpp0083905.

Structurei

3D structure databases

ProteinModelPortaliQ7KS38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3411. Eukaryota.
COG2238. LUCA.
GeneTreeiENSGT00390000013102.
InParanoidiQ7KS38.
KOiK02966.
OMAiRMVEKHP.
OrthoDBiEOG091G0QM7.
PhylomeDBiQ7KS38.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001266. Ribosomal_S19e.
IPR018277. Ribosomal_S19e_CS.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11710. PTHR11710. 1 hit.
PfamiView protein in Pfam
PF01090. Ribosomal_S19e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003854. Ribosomal_S19e. 1 hit.
SMARTiView protein in SMART
SM01413. Ribosomal_S19e. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00628. RIBOSOMAL_S19E. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7KS38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGVTVKEID QHVLTKNMAA FLKKSGKIFV PEQAVYMKTG KFKETAPTDD
60 70 80 90 100
DWFYTRCASI MRHLYLRSPA GVGAFTKVYS GRKRNGVRPS KHCRSSDGCI
110 120 130 140 150
RKALQALEAA NMVERHPDGG RKLTPQGQRN LDRIANKIVA KQRERSAPVS

MIITT
Length:155
Mass (Da):17,362
Last modified:January 23, 2007 - v3
Checksum:i83275522909BCD0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAN13960.1.
AY119257 mRNA. Translation: AAM51117.1.
RefSeqiNP_001262891.1. NM_001275962.1.
NP_651195.1. NM_142938.2.
UniGeneiDm.20517.

Genome annotation databases

EnsemblMetazoaiFBtr0084519; FBpp0083905; FBgn0039129.
FBtr0332444; FBpp0304717; FBgn0039129.
GeneIDi42830.
KEGGidme:Dmel_CG5338.

Similar proteinsi

Entry informationi

Entry nameiRS19B_DROME
AccessioniPrimary (citable) accession number: Q7KS38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2004
Last sequence update: January 23, 2007
Last modified: September 27, 2017
This is version 106 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families