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Q7KNF1 (Q7KNF1_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Drosha EMBL AAF59169.1
EC=3.1.26.3 EMBL AAF59169.1
Submitted name:
LD20030p EMBL AAY84903.1
Submitted name:
Ribonuclease EMBL AAD31170.1
Gene names
Name:drosha FlyBase FBgn0026722 EMBL AAD31170.1
ORF Names:CG8730 FlyBase FBgn0026722, Dmel_CG8730 EMBL AAF59169.1
OrganismDrosophila melanogaster (Fruit fly) EMBL AAD31170.1
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length1327 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Sequences

Sequence LengthMass (Da)Tools
Q7KNF1 [UniParc].

Last modified October 3, 2006. Version 1.
Checksum: 84AD3AABD676C9E8

FASTA1,327152,817
        10         20         30         40         50         60 
MYQPPLPPPP VQPAPPPPPP PPEEDLSPPG VGVPSHNYSS NESHSQSSKS LDYVYPETPA 

        70         80         90        100        110        120 
PYASSVPSYD PYQQPPAYGY EGYAYNEQAQ KYGGQESHYQ YQYPASGSSF LYESYKYPDR 

       130        140        150        160        170        180 
YPAYSSNYRP PSERQRYTSN SSSQGYHHYP GYSSGRRYEQ RHDQEHRQIQ DSRYAHEPRH 

       190        200        210        220        230        240 
GHYAHRQAKG SQHGYYGSAA RNQVSDDYSP RGHHERERNE TLEKTRAKPK VETERDRLLR 

       250        260        270        280        290        300 
QWCSNFCEKP EDYVKKMNAL SEADAPVESW VRSSPAELYY ERTKSENEVR GRARLQKLCT 

       310        320        330        340        350        360 
LFDEELLQRA KRVREKLPVY VPPPRKARRR VCKHKHKSEA CSSSSSSDDD SDEDAFKIEQ 

       370        380        390        400        410        420 
DCCMEELSRK VQHPQRVHAD LWHNDAGEMN DGPLCRCSAK SRRIGIRHGI YPGETGYKLC 

       430        440        450        460        470        480 
DPNSNNAGKL FHYRISISPP TNFLTKTPTI IKHDEHEFLF EGFSLLSHVR LSDLPVCKVI 

       490        500        510        520        530        540 
RFNIEYTIEY EEEKMPENFT IHELDIFFKY LFHELLELVD FNLMPNLPSG NVEESCPAFH 

       550        560        570        580        590        600 
FFPRFVRDLP DNGKEVLAMV EVLRYLLDNS AQLVERQQLL HLNQISQSEW QNYVDFIKGM 

       610        620        630        640        650        660 
LVTKPGYKPC SLRVDQLDRN NSDLPECVDR ETGISHPAIV HFGICHPQLS YAGNPEYQKA 

       670        680        690        700        710        720 
WREYVKYRHL MANMSKPSFK DKRKLEEKEQ RLQEMRTQGR MKRNITVAIS SEGFYRTGIM 

       730        740        750        760        770        780 
CDVVQHAMLI PVLTGHLRFH KSLDLLEESI GYRFKNRYLL QLALTHPSYK ENYGTNPDHA 

       790        800        810        820        830        840 
RNSLTNCGIR QPEYGDRKIH YMNTRKRGIN TLVSIMSRFG KEHETVSNIT HNERLEFLGD 

       850        860        870        880        890        900 
AVVEFLSSIH LFFMFPELEE GGLATYRAAI VQNQHLALLA KKLQLEEFML YAHGSDLCHE 

       910        920        930        940        950        960 
LELRHAMANC FEALMGALLL DGGIKVADEV FTDALFRQDE KLLSIWKNLP EHPLQEQEPL 

       970        980        990       1000       1010       1020 
GDRSCIDSYR VLKELTKFED SIGIKFKHIR LLARAFTDRS IGFTHLTLGS NQRLEFLGDT 

      1030       1040       1050       1060       1070       1080 
VLQLICSEYL YRHFPEHHEG HLSLLRSSLV NNRTQAVVCD DLGMPKYAVY ANPKADLKTK 

      1090       1100       1110       1120       1130       1140 
DRADLLEAFL GALYVDKGLL YCEQFCHVCL FPRLQLFIMN QDWNDPKSKL QQCCLTLRTM 

      1150       1160       1170       1180       1190       1200 
DGGEPDIPYY KVVEASGPTN TRVYKVAVYF RSKRLATSSG SSIQQAEMNA AKQALENSRD 

      1210       1220       1230       1240       1250       1260 
LFPQLDHQKR VIAKSIKKQT GNELDNDSDR QHQEEKIKRP KYATPLQDES HLPKQYRMHE 

      1270       1280       1290       1300       1310       1320 
NISSDELPED EDFESTAPKS PTMPLRSNRS GSSSSSSSSD SDGSTSSPKC KRRLKKCSSV 


SSKSSLG

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"A novel type of RNase III family proteins in eukaryotes."
Filippov V., Solovyev V., Filippova M., Gill S.S.
Gene 245:213-221(2000) [PubMed: 10713462] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
[4]Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Celniker S.
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley EMBL AAY84903.1.
[5]Filippov V.A., Filippova M.A., Gill S.S.
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF116572 mRNA. Translation: AAD31170.1.
AE013599 Genomic DNA. Translation: AAF59169.1.
BT023503 mRNA. Translation: AAY84903.1.
RefSeqNP_477436.1. NM_058088.3.
UniGeneDm.4482.

3D structure databases

HSSPHSSP built from PDB template 1JFZ based on UniProtKB O67082.
ProteinModelPortalQ7KNF1.
SMRQ7KNF1. Positions 741-935, 973-1205.
ModBaseSearch...

Protein-protein interaction databases

IntActQ7KNF1. 1 interaction.
STRINGQ7KNF1.

Proteomic databases

PRIDEQ7KNF1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0088850; FBpp0087926; FBgn0026722.
GeneID35747.
KEGGdme:Dmel_CG8730.
UCSCCG8730-RA. d. melanogaster.

Organism-specific databases

CTD29102.
FlyBaseFBgn0026722. drosha.

Phylogenomic databases

InParanoidQ7KNF1.
OMAAFTDRSI.
OrthoDBEOG4BRV1K.
PhylomeDBQ7KNF1.

Gene expression databases

ArrayExpressQ7KNF1.
BgeeQ7KNF1.

Family and domain databases

InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like.
IPR000999. RNase_III.
IPR011907. RNase_III_bac.
[Graphical view]
Gene3DG3DSA:3.30.160.20. dsRNA-bd-like. 1 hit.
G3DSA:1.10.1520.10. RNase_III. 3 hits.
KOK03685.
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 2 hits.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 2 hits.
[Graphical view]
SUPFAMSSF69065. RNase_III. 2 hits.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio795024.

Entry information

Entry nameQ7KNF1_DROME
AccessionPrimary (citable) accession number: Q7KNF1
Entry history
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info