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Protein

Dymeclin

Gene

CG8230

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Dymeclin
Gene namesi
ORF Names:CG8230
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0027607. CG8230.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 699698DymeclinPRO_0000348215Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineBy similarity
Modified residuei346 – 3461Phosphoserine2 Publications

Keywords - PTMi

Lipoprotein, Myristate, Phosphoprotein

Proteomic databases

PaxDbiQ7KNA0.
PRIDEiQ7KNA0.

PTM databases

iPTMnetiQ7KNA0.

Expressioni

Gene expression databases

BgeeiQ7KNA0.
GenevisibleiQ7KNA0. DM.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CG5745Q95RC51EBI-131459,EBI-138805
CG6506Q9VX121EBI-131459,EBI-159142

Protein-protein interaction databases

BioGridi61735. 8 interactions.
IntActiQ7KNA0. 10 interactions.
STRINGi7227.FBpp0087755.

Family & Domainsi

Sequence similaritiesi

Belongs to the dymeclin family.Curated

Phylogenomic databases

eggNOGiKOG2225. Eukaryota.
ENOG410XP0J. LUCA.
GeneTreeiENSGT00390000008772.
InParanoidiQ7KNA0.
OMAiIQNIDMV.
OrthoDBiEOG72ZCG2.
PhylomeDBiQ7KNA0.

Family and domain databases

InterProiIPR019142. Dymeclin.
[Graphical view]
PANTHERiPTHR12895:SF9. PTHR12895:SF9. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7KNA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGINVSRTAD LGSNQWLQRF VGRQHIAHDD EAFWNGLLNY NIVLPENSQD
60 70 80 90 100
QLNLDSRLEA LCQSFIGNNL KTGNFGSLVT VFLEKTSELL SLSDQESNMH
110 120 130 140 150
VWQTFNALFI IRSLVKYINE TGSEFQLLQH FEAMPNAELL QAALEQQQQT
160 170 180 190 200
PAESATIAME ATEQSAAAAV PVIVDGSKFE TFIDALVNLI VVIPVKEFTY
210 220 230 240 250
HLHLEAVNML ITLLSVHLFA QQPTDKSIVF RTVFKCQHAN VLMSALLHFV
260 270 280 290 300
ARIVEVPHTM FGSSSAGSFV FGIAESLLSI FTFRKQPDIL KAGQAAGGGE
310 320 330 340 350
LSQRFRTHYP LANQSLLLIL ILTNHCTAQD NAYRTSLFSC ADSKDSPKQG
360 370 380 390 400
AVSFQIDFSA VYETLCTIVT IDQATLLLYL LLHRNERFYR FVMQQQDLEQ
410 420 430 440 450
LVIPILQTLY NAPDSNSHHI YMSLIVLLIL SEDEGFNKNV HTIMLKNITW
460 470 480 490 500
YTERTISEIS LGGILILIVI RTIQYNMLKM RDKYLHTNCL AALANMSGHF
510 520 530 540 550
RALHPYVAQR LVSLFETLAR KHTRLDAQLK EPADSAVFVN VSTTPEDMLQ
560 570 580 590 600
DLSVLEEVLR MVLEILNSCL TNQLVYCPNL VYTLLYKRSV FEGFRSHHAF
610 620 630 640 650
QDVIQNIDMV VGFFSSRLQR VQEQRGELGV NEVLEVISKG ASQWSSDRLR
660 670 680 690
KFPDLKFKYV EEDAPEEFFI PYVWTLVCKY GCVHFSSESI KSVTTDIAC
Length:699
Mass (Da):79,125
Last modified:October 3, 2006 - v1
Checksum:i3C73F8499D2F3E55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59014.1.
AF132149 mRNA. Translation: AAD34737.1.
RefSeqiNP_610431.1. NM_136587.3.
UniGeneiDm.536.

Genome annotation databases

EnsemblMetazoaiFBtr0088674; FBpp0087755; FBgn0027607.
GeneIDi35897.
KEGGidme:Dmel_CG8230.
UCSCiCG8230-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59014.1.
AF132149 mRNA. Translation: AAD34737.1.
RefSeqiNP_610431.1. NM_136587.3.
UniGeneiDm.536.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi61735. 8 interactions.
IntActiQ7KNA0. 10 interactions.
STRINGi7227.FBpp0087755.

PTM databases

iPTMnetiQ7KNA0.

Proteomic databases

PaxDbiQ7KNA0.
PRIDEiQ7KNA0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0088674; FBpp0087755; FBgn0027607.
GeneIDi35897.
KEGGidme:Dmel_CG8230.
UCSCiCG8230-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0027607. CG8230.

Phylogenomic databases

eggNOGiKOG2225. Eukaryota.
ENOG410XP0J. LUCA.
GeneTreeiENSGT00390000008772.
InParanoidiQ7KNA0.
OMAiIQNIDMV.
OrthoDBiEOG72ZCG2.
PhylomeDBiQ7KNA0.

Miscellaneous databases

GenomeRNAii35897.
PROiQ7KNA0.

Gene expression databases

BgeeiQ7KNA0.
GenevisibleiQ7KNA0. DM.

Family and domain databases

InterProiIPR019142. Dymeclin.
[Graphical view]
PANTHERiPTHR12895:SF9. PTHR12895:SF9. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  2. Cited for: GENOME REANNOTATION.
    Strain: Berkeley.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Berkeley.
    Tissue: Head.
  4. "An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells."
    Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D., Juenger M.A., Eng J.K., Aebersold R., Tao W.A.
    Mol. Biosyst. 3:275-286(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-346, IDENTIFICATION BY MASS SPECTROMETRY.
  5. "Phosphoproteome analysis of Drosophila melanogaster embryos."
    Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
    J. Proteome Res. 7:1675-1682(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-346, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Embryo.

Entry informationi

Entry nameiDYM_DROME
AccessioniPrimary (citable) accession number: Q7KNA0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 3, 2006
Last modified: June 8, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.