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Protein
Submitted name:

Ercc1

Gene

Ercc1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • meiotic mismatch repair Source: GO_Central
  • mitotic recombination Source: GO_Central
  • neuron projection morphogenesis Source: FlyBase
  • nucleotide-excision repair Source: FlyBase
  • nucleotide-excision repair, DNA incision, 5'-to lesion Source: FlyBase
  • reciprocal meiotic recombination Source: FlyBase
  • resolution of meiotic recombination intermediates Source: FlyBase
  • UV-damage excision repair Source: GO_Central

Enzyme and pathway databases

ReactomeiR-DME-5696395. Formation of Incision Complex in GG-NER.
R-DME-5696400. Dual Incision in GG-NER.
R-DME-6782135. Dual incision in TC-NER.

Names & Taxonomyi

Protein namesi
Submitted name:
Ercc1Imported
Submitted name:
Nucleotide excision repair protein ERCC1Imported
Gene namesi
Name:Ercc1Imported
ORF Names:CG10215Imported, Dmel_CG10215Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0028434. Ercc1.

Subcellular locationi

GO - Cellular componenti

  • ERCC4-ERCC1 complex Source: GO_Central
  • nucleotide-excision repair factor 1 complex Source: GO_Central
  • protein complex Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0028434.

Interactioni

GO - Molecular functioni

  • protein heterodimerization activity Source: FlyBase

Protein-protein interaction databases

IntActiQ7KMG7. 3 interactors.
STRINGi7227.FBpp0086578.

Structurei

3D structure databases

SMRiQ7KMG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2841. Eukaryota.
COG5241. LUCA.
GeneTreeiENSGT00390000011275.
KOiK10849.
OMAiLNPDYIC.
OrthoDBiEOG091G0IRO.

Family and domain databases

InterProiView protein in InterPro
IPR004579. ERCC1/RAD10/SWI10.
IPR011335. Restrct_endonuc-II-like.
IPR010994. RuvA_2-like.
PANTHERiPTHR12749. PTHR12749. 1 hit.
PfamiView protein in Pfam
PF03834. Rad10. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013585. DNA_repair_Rad10. 1 hit.
SUPFAMiSSF47781. SSF47781. 1 hit.
SSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR00597. rad10. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7KMG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDFDDDSFN DVLGAMEMPT AAKQPKVDAP AATAVNPAPS NSTEPSGSGR
60 70 80 90 100
PAPGKPASNP HCVLVHSKQR GNPILKSILN VPLEFRDDIV PDYVVGRTSC
110 120 130 140 150
VLYLSLKYHN LNPDYICQRL KALGKMYELR VLLVQVDTPE PNNALKSLTR
160 170 180 190 200
ISLLADLTMM LAWNAEEAGK IIETYKQFEK RPPDLIMERV ESNPHQKLLA
210 220 230 240 250
ALTNIKPVNK TDAAALLHTF GNLGNIINAS EERLSQVMGL GPRKAKKLYK

TLQEPFLSK
Length:259
Mass (Da):28,583
Last modified:October 3, 2006 - v1
Checksum:i2F78464CF3F3389C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF146797 Genomic DNA. Translation: AAD38010.1.
AE013599 Genomic DNA. Translation: AAF58196.1.
RefSeqiNP_477468.1. NM_058120.3.

Genome annotation databases

EnsemblMetazoaiFBtr0087448; FBpp0086578; FBgn0028434.
GeneIDi36654.
KEGGidme:Dmel_CG10215.
UCSCiCG10215-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ7KMG7_DROME
AccessioniPrimary (citable) accession number: Q7KMG7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: August 30, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported