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Protein
Submitted name:

Ercc1

Gene

Ercc1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • meiotic mismatch repair Source: GO_Central
  • mitotic recombination Source: GO_Central
  • nucleotide-excision repair Source: FlyBase
  • nucleotide-excision repair, DNA incision, 5'-to lesion Source: FlyBase
  • reciprocal meiotic recombination Source: FlyBase
  • resolution of meiotic recombination intermediates Source: FlyBase
  • UV-damage excision repair Source: GO_Central

Enzyme and pathway databases

ReactomeiR-DME-5696395 Formation of Incision Complex in GG-NER
R-DME-5696400 Dual Incision in GG-NER
R-DME-6782135 Dual incision in TC-NER

Names & Taxonomyi

Protein namesi
Submitted name:
Ercc1Imported
Submitted name:
Nucleotide excision repair protein ERCC1Imported
Gene namesi
Name:Ercc1Imported
ORF Names:CG10215Imported, Dmel_CG10215Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0028434 Ercc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0028434

Interactioni

GO - Molecular functioni

  • protein heterodimerization activity Source: FlyBase

Protein-protein interaction databases

STRINGi7227.FBpp0086578

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2841 Eukaryota
COG5241 LUCA
GeneTreeiENSGT00390000011275
KOiK10849
OMAiLNPDYIC
OrthoDBiEOG091G0IRO

Family and domain databases

InterProiView protein in InterPro
IPR004579 ERCC1/RAD10/SWI10
IPR011335 Restrct_endonuc-II-like
IPR010994 RuvA_2-like
PANTHERiPTHR12749 PTHR12749, 1 hit
PfamiView protein in Pfam
PF03834 Rad10, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013585 DNA_repair_Rad10, 1 hit
SUPFAMiSSF47781 SSF47781, 1 hit
SSF52980 SSF52980, 1 hit
TIGRFAMsiTIGR00597 rad10, 1 hit

Sequencei

Sequence statusi: Complete.

Q7KMG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDFDDDSFN DVLGAMEMPT AAKQPKVDAP AATAVNPAPS NSTEPSGSGR
60 70 80 90 100
PAPGKPASNP HCVLVHSKQR GNPILKSILN VPLEFRDDIV PDYVVGRTSC
110 120 130 140 150
VLYLSLKYHN LNPDYICQRL KALGKMYELR VLLVQVDTPE PNNALKSLTR
160 170 180 190 200
ISLLADLTMM LAWNAEEAGK IIETYKQFEK RPPDLIMERV ESNPHQKLLA
210 220 230 240 250
ALTNIKPVNK TDAAALLHTF GNLGNIINAS EERLSQVMGL GPRKAKKLYK

TLQEPFLSK
Length:259
Mass (Da):28,583
Last modified:October 3, 2006 - v1
Checksum:i2F78464CF3F3389C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF146797 Genomic DNA Translation: AAD38010.1
AE013599 Genomic DNA Translation: AAF58196.1
RefSeqiNP_477468.1, NM_058120.3

Genome annotation databases

EnsemblMetazoaiFBtr0087448; FBpp0086578; FBgn0028434
GeneIDi36654
KEGGidme:Dmel_CG10215
UCSCiCG10215-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ7KMG7_DROME
AccessioniPrimary (citable) accession number: Q7KMG7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: June 20, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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