Q7KJV6 (Q7KJV6_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ubiquitin-like protein activating enzyme EMBL AAF25197.1

Gene names

Name:

Uba2 EMBL AAF25197.1 FlyBase FBgn0029113

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	700 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	humoral immune response Inferred from mutant phenotype. Source: FlyBase positive regulation of NF-kappaB transcription factor activity Inferred from direct assay. Source: FlyBase protein modification process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from direct assay Ref.1. Source: FlyBase nucleus Inferred from direct assay Ref.1. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction Ref.1. Source: FlyBase small protein activating enzyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7KJV6 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 5C54D0B6C2A15863	FASTA	700	77,595
	10 20 30 40 50 60 MAAAINGVFP PTLQELVKKS KVLVVGAGGI GCEVLKNLVL SGFTDIEIID LDTIDLSNLN 70 80 90 100 110 120 RQFLFHREHV GKSKARVARE SALSFNPDAK ITAYHDSVTS TDYGVNFFKK FDLVLSALDN 130 140 150 160 170 180 RAARNHVNRM CLNADVPLIE SGTAGYNGQV ELIKRGLTQC YECTPKDKQR SFPGCTIRNT 190 200 210 220 230 240 PSEPIHCIVW AKHLFNQLFG ESLEDEDISP DAADPDAKEK DGGDGNGEPK GDGKEKGEES 250 260 270 280 290 300 KEEKEAKEDT ANGNIMRINT RQWAKDSNYD AGKLFNKFFN EDITYLLRMS NLWKTRKAPV 310 320 330 340 350 360 PVQWDTLLPE GSSGDQKDVA KQHHKVWSIE ECAQVFANSL KELSANFLKL EGDDTLAWDK 370 380 390 400 410 420 DDQPAMDFVA ACANVRSHIF DIERKSRFEI KSMAGNIIPA IATTNAITAG ISVMRAFKVL 430 440 450 460 470 480 EAKWEQCKAV YARLRPNARN HFLVPDASLP GPNPNCHVCA SDPAITLKID TKRMRIKELR 490 500 510 520 530 540 DEVLVKTLNM LNPDVTVQSN GSILISSEEG ETECNDGKLL SELNIVDGVI LKCDDFFQNY 550 560 570 580 590 600 ELSIIISHFD AERDENLFEV VADASQLKPK DEDQKEAVKD KEDEPKSAKK RSTNGEGDSK 610 620 630 640 650 660 DDGPSTSKRS RPNEVVEEDD DDCLVIEEDE DQADVVVVAT DKLSVQSPPK SGSKRKPCEV 670 680 690 700 IEDEDITEIL ESSDDEPAGP TKCKRSRLDD SNPVAVISID

References

[1]	"Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila." Shih H.-P., Hales K.G., Pringle J.R., Peifer M. J. Cell Sci. 115:1259-1271(2002) [PubMed: 11884525] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF193553 mRNA. Translation: AAF25197.1.
3D structure databases
HSSP	HSSP built from PDB template 1JWA based on UniProtKB P12282.
ProteinModelPortal	Q7KJV6.
SMR	Q7KJV6. Positions 7-565.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7KJV6.
Proteomic databases
PRIDE	Q7KJV6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0029113. Uba2.
Phylogenomic databases
eggNOG	inNOG04054.
InParanoid	Q7KJV6.
OrthoDB	EOG45MKMD.
Gene expression databases
ArrayExpress	Q7KJV6.
Bgee	Q7KJV6.
Family and domain databases
InterPro	IPR009036. Molybdenum_cofac_synth_MoeB. IPR016040. NAD(P)-bd_dom. IPR000594. ThiF_NAD_FAD-bd. IPR023280. Ub-like_act_enz_cat_cys_dom. IPR000127. UBact_repeat. IPR019572. Ubiquitin-activating_enzyme. IPR018074. UBQ-activ_enz_E1_AS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 2 hits. G3DSA:1.10.3240.10. Ub-like_act_enz_cat_cys_dom. 1 hit.
Pfam	PF00899. ThiF. 1 hit. PF10585. UBA_e1_thiolCys. 1 hit. PF02134. UBACT. 1 hit. [Graphical view]
SUPFAM	SSF69572. MoeB. 1 hit.
PROSITE	PS00865. UBIQUITIN_ACTIVAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7KJV6_DROME

Accession

Primary (citable) accession number: Q7KJV6

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)